Product Information

URSODIOL 250 MG TABLET is a generic product labeled by Endo USA Inc., priced at $0.4502 per EA under NDC 49884041201. Its NADAC has been published 650 times since Mar 12, 2014.

FDA first approved this application on Feb 14, 2013. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

URSODIOL 250 MG TABLET

Ursodiol
$0.4502per EA

Strength

250 mg/1

Manufacturer

Endo USA Inc.

NDC

49884041201

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

URSODIOL

Approval Type

Generic (ANDA)

FDA Application

ANDA202540

FDA Approved

2/14/2013

TE Code

AB

On Market Since

8/1/2013

Pharmacological Classes

Bile Acid
Bile Acids and Salts

Price Statistics

The NADAC for URSODIOL 250 MG TABLET has been published 650 times since Mar 12, 2014, and over the history we have for it it has declined 69.4%. The table below summarizes its recorded NADAC range and movement.

Current price$0.4502 per EA
All-time high$1.7992 (Aug 12, 2015)
All-time low$0.2571 (Jul 17, 2024)
52-week high$0.4550
52-week low$0.3317
Median price$0.8440
Average price$0.8921
Largest weekly change+77.9% (Aug 21, 2024)
Weeks tracked650
Tracking sinceMar 12, 2014

Price History

1W

-1.1%

1M

-1.1%

3M

+4.8%

6M

+10.8%

1Y

+35.7%

3Y

-7.1%

5Y

-41.6%

All

-69.4%

Generic Alternatives

The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 5% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of URSODIOL 250 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for URSODIOL 250 MG TABLET, manufactured by Endo USA Inc., is $0.4502 per EA (NDC 49884041201), effective Aug 19, 2026.

How has the price of URSODIOL 250 MG TABLET changed over time?

Over the history we have for it, the NADAC for URSODIOL 250 MG TABLET has declined 69.4%. It has been tracked across 650 weekly CMS publications since Mar 12, 2014.

What are the highest and lowest recorded NADAC prices for URSODIOL 250 MG TABLET?

Since Mar 12, 2014, the NADAC for URSODIOL 250 MG TABLET has ranged from a low of $0.2571 (Jul 17, 2024) to a high of $1.7992 (Aug 12, 2015), with a median of $0.8440 per EA.

Are there cheaper alternatives to URSODIOL 250 MG TABLET?

Yes. 6 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, URSODIOL 250 MG TABLET, is $0.4295 per EA — about 5% below URSODIOL 250 MG TABLET.

Who manufactures URSODIOL 250 MG TABLET?

URSODIOL 250 MG TABLET (NDC 49884041201) is labeled by Endo USA Inc., and CMS classifies it as a generic product.