Product Information

LAMOTRIGINE ODT 25 MG TABLET is a generic product labeled by Endo USA Inc., priced at $1.2668 per EA under NDC 49884048411. Its NADAC has been published 523 times since May 18, 2016.

FDA first approved this application on Oct 27, 2015. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The High Outlier badge above means this manufacturer's average price in the Lamotrigine market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

LAMOTRIGINE ODT 25 MG TABLET

Lamotrigine
$1.2668per EA
High Outlier

Strength

25 mg/1

Manufacturer

Endo USA Inc.

NDC

49884048411

Classification

Generic

Dosage Form

TABLET, ORALLY DISINTEGRATING

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

LAMOTRIGINE

Approval Type

Generic (ANDA)

FDA Application

ANDA204158

FDA Approved

10/27/2015

TE Code

AB

On Market Since

12/16/2015

Pharmacological Classes

Anti-epileptic Agent
Decreased Central Nervous System Disorganized Electrical Activity
Dihydrofolate Reductase Inhibitors
Mood Stabilizer
Organic Cation Transporter 2 Inhibitors

Price Statistics

The NADAC for LAMOTRIGINE ODT 25 MG TABLET has been published 523 times since May 18, 2016, and over the history we have for it it has declined 79.6%. The table below summarizes its recorded NADAC range and movement.

Current price$1.2668 per EA
All-time high$6.2049 (Jul 13, 2016)
All-time low$1.0506 (May 20, 2026)
52-week high$1.8894
52-week low$1.0506
Median price$4.2213
Average price$3.8070
Largest weekly change+75.0% (Jan 17, 2024)
Weeks tracked523
Tracking sinceMay 18, 2016

Price History

1W

+0.3%

1M

+0.3%

3M

+20.6%

6M

-14.4%

1Y

-28.6%

3Y

-31.0%

5Y

-70.0%

All

-79.6%

Generic Alternatives

The matcher finds 19 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 98% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of LAMOTRIGINE ODT 25 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for LAMOTRIGINE ODT 25 MG TABLET, manufactured by Endo USA Inc., is $1.2668 per EA (NDC 49884048411), effective Aug 19, 2026.

How has the price of LAMOTRIGINE ODT 25 MG TABLET changed over time?

Over the history we have for it, the NADAC for LAMOTRIGINE ODT 25 MG TABLET has declined 79.6%. It has been tracked across 523 weekly CMS publications since May 18, 2016.

What are the highest and lowest recorded NADAC prices for LAMOTRIGINE ODT 25 MG TABLET?

Since May 18, 2016, the NADAC for LAMOTRIGINE ODT 25 MG TABLET has ranged from a low of $1.0506 (May 20, 2026) to a high of $6.2049 (Jul 13, 2016), with a median of $4.2213 per EA.

Are there cheaper alternatives to LAMOTRIGINE ODT 25 MG TABLET?

Yes. 19 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, LAMOTRIGINE 25 MG TABLET, is $0.0271 per EA — about 98% below LAMOTRIGINE ODT 25 MG TABLET.

Who manufactures LAMOTRIGINE ODT 25 MG TABLET?

LAMOTRIGINE ODT 25 MG TABLET (NDC 49884048411) is labeled by Endo USA Inc., and CMS classifies it as a generic product.