Product Information
ISOSORBIDE DINITRATE 40 MG TAB is a generic product labeled by Endo USA Inc., priced at $3.3103 per EA under NDC 49884055601. Its NADAC has been published 111 times since Aug 21, 2024.
FDA first approved this application on Nov 23, 2021. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
40 mg/1
Manufacturer
Endo USA Inc.NDC
49884055601
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
ISOSORBIDE DINITRATEApproval Type
Generic (ANDA)
FDA Application
ANDA211290FDA Approved
11/23/2021
TE Code
AB
On Market Since
12/21/2021
Pharmacological Classes
Price Statistics
The NADAC for ISOSORBIDE DINITRATE 40 MG TAB has been published 111 times since Aug 21, 2024, and over the history we have for it it has risen 49.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $3.3103 per EA |
|---|---|
| All-time high | $3.3103 (Sep 30, 2026) |
| All-time low | $1.8875 (Oct 23, 2024) |
| 52-week high | $3.3103 |
| 52-week low | $2.5851 |
| Median price | $2.5349 |
| Average price | $2.5564 |
| Largest weekly change | +13.4% (Mar 19, 2025) |
| Weeks tracked | 111 |
| Tracking since | Aug 21, 2024 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Isosorbide Dinitrate market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Endo USA Inc. manufacturer profile
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Drug market
Isosorbide Dinitrate market comparison
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Therapeutic class
Nitrate Vasodilator class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
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Frequently asked questions
What is the NADAC price of ISOSORBIDE DINITRATE 40 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for ISOSORBIDE DINITRATE 40 MG TAB, manufactured by Endo USA Inc., is $3.3103 per EA (NDC 49884055601), effective Sep 30, 2026.
How has the price of ISOSORBIDE DINITRATE 40 MG TAB changed over time?
Over the history we have for it, the NADAC for ISOSORBIDE DINITRATE 40 MG TAB has risen 49.4%. It has been tracked across 111 weekly CMS publications since Aug 21, 2024.
What are the highest and lowest recorded NADAC prices for ISOSORBIDE DINITRATE 40 MG TAB?
Since Aug 21, 2024, the NADAC for ISOSORBIDE DINITRATE 40 MG TAB has ranged from a low of $1.8875 (Oct 23, 2024) to a high of $3.3103 (Sep 30, 2026), with a median of $2.5349 per EA.
Are there cheaper alternatives to ISOSORBIDE DINITRATE 40 MG TAB?
No other NADAC-published product currently shares the active ingredient and strength of ISOSORBIDE DINITRATE 40 MG TAB in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures ISOSORBIDE DINITRATE 40 MG TAB?
ISOSORBIDE DINITRATE 40 MG TAB (NDC 49884055601) is labeled by Endo USA Inc., and CMS classifies it as a generic product.