Product Information
MIDODRINE HCL 5 MG TABLET is a generic product labeled by Endo USA Inc., priced at $0.1113 per EA under NDC 49884084901. Its NADAC has been published 399 times since Feb 13, 2019.
FDA first approved this application on Oct 29, 2018. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
5 mg/1
Manufacturer
Endo USA Inc.NDC
49884084901
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
MIDODRINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA207169FDA Approved
10/29/2018
TE Code
AB
On Market Since
10/29/2018
Pharmacological Classes
Price Statistics
The NADAC for MIDODRINE HCL 5 MG TABLET has been published 399 times since Feb 13, 2019, and over the history we have for it it has declined 75.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1113 per EA |
|---|---|
| All-time high | $0.4763 (Mar 13, 2019) |
| All-time low | $0.1084 (Feb 18, 2026) |
| 52-week high | $0.1148 |
| 52-week low | $0.1084 |
| Median price | $0.2426 |
| Average price | $0.2570 |
| Largest weekly change | +38.5% (Aug 21, 2024) |
| Weeks tracked | 399 |
| Tracking since | Feb 13, 2019 |
Generic Alternatives
The matcher finds 11 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Endo USA Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Midodrine Hydrochloride market comparison
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Therapeutic class
alpha-Adrenergic Agonist class view
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Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of MIDODRINE HCL 5 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for MIDODRINE HCL 5 MG TABLET, manufactured by Endo USA Inc., is $0.1113 per EA (NDC 49884084901), effective Sep 30, 2026.
How has the price of MIDODRINE HCL 5 MG TABLET changed over time?
Over the history we have for it, the NADAC for MIDODRINE HCL 5 MG TABLET has declined 75.3%. It has been tracked across 399 weekly CMS publications since Feb 13, 2019.
What are the highest and lowest recorded NADAC prices for MIDODRINE HCL 5 MG TABLET?
Since Feb 13, 2019, the NADAC for MIDODRINE HCL 5 MG TABLET has ranged from a low of $0.1084 (Feb 18, 2026) to a high of $0.4763 (Mar 13, 2019), with a median of $0.2426 per EA.
Are there cheaper alternatives to MIDODRINE HCL 5 MG TABLET?
11 manufacturers publish a NADAC-priced product with the same active ingredient and strength as MIDODRINE HCL 5 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures MIDODRINE HCL 5 MG TABLET?
MIDODRINE HCL 5 MG TABLET (NDC 49884084901) is labeled by Endo USA Inc., and CMS classifies it as a generic product.