Product Information

DIVALPROEX SOD ER 250 MG TAB is a generic product labeled by AvPAK, priced at $0.1287 per EA under NDC 50268025915. Its NADAC has been published 184 times since Feb 15, 2023.

FDA first approved this application on May 29, 2015. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

DIVALPROEX SOD ER 250 MG TAB

Divalproex Sodium
$0.1287per EA

Strength

250 mg/1

Manufacturer

AvPAK

NDC

50268025915

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

DIVALPROEX SODIUM

Approval Type

Generic (ANDA)

FDA Application

ANDA203730

FDA Approved

5/29/2015

TE Code

AB

On Market Since

9/16/2022

Pharmacological Classes

Anti-epileptic Agent
Decreased Central Nervous System Disorganized Electrical Activity
Mood Stabilizer

Price Statistics

The NADAC for DIVALPROEX SOD ER 250 MG TAB has been published 184 times since Feb 15, 2023, and over the history we have for it it has declined 17.9%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1287 per EA
All-time high$0.1843 (Nov 15, 2023)
All-time low$0.1159 (Nov 20, 2024)
52-week high$0.1529
52-week low$0.1287
Median price$0.1466
Average price$0.1509
Largest weekly change-33.2% (Nov 20, 2024)
Weeks tracked184
Tracking sinceFeb 15, 2023

Price History

1W

-4.9%

1M

-4.9%

3M

-6.9%

6M

-2.5%

1Y

-15.8%

3Y

-25.3%

5Y

N/A

All

-17.9%

Generic Alternatives

The matcher finds 11 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 35% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of DIVALPROEX SOD ER 250 MG TAB?

The current National Average Drug Acquisition Cost (NADAC) for DIVALPROEX SOD ER 250 MG TAB, manufactured by AvPAK, is $0.1287 per EA (NDC 50268025915), effective Aug 19, 2026.

How has the price of DIVALPROEX SOD ER 250 MG TAB changed over time?

Over the history we have for it, the NADAC for DIVALPROEX SOD ER 250 MG TAB has declined 17.9%. It has been tracked across 184 weekly CMS publications since Feb 15, 2023.

What are the highest and lowest recorded NADAC prices for DIVALPROEX SOD ER 250 MG TAB?

Since Feb 15, 2023, the NADAC for DIVALPROEX SOD ER 250 MG TAB has ranged from a low of $0.1159 (Nov 20, 2024) to a high of $0.1843 (Nov 15, 2023), with a median of $0.1466 per EA.

Are there cheaper alternatives to DIVALPROEX SOD ER 250 MG TAB?

Yes. 11 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DIVALPROEX SOD DR 250 MG TAB, is $0.0833 per EA — about 35% below DIVALPROEX SOD ER 250 MG TAB.

Who manufactures DIVALPROEX SOD ER 250 MG TAB?

DIVALPROEX SOD ER 250 MG TAB (NDC 50268025915) is labeled by AvPAK, and CMS classifies it as a generic product.