Product Information
DOXYCYCLINE MONO 100 MG CAP is a generic product labeled by AvPAK, priced at $0.2267 per EA under NDC 50268028115. Its NADAC has been published 308 times since Nov 11, 2020.
FDA first approved this application on Feb 18, 2016. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
100 mg/1
Manufacturer
AvPAKNDC
50268028115
Classification
Generic
Dosage Form
CAPSULE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
DOXYCYCLINEApproval Type
Generic (ANDA)
FDA Application
ANDA205115FDA Approved
2/18/2016
TE Code
AB
On Market Since
5/15/2020
Pharmacological Classes
Price Statistics
The NADAC for DOXYCYCLINE MONO 100 MG CAP has been published 308 times since Nov 11, 2020, and over the history we have for it it has declined 15.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2267 per EA |
|---|---|
| All-time high | $0.2875 (Apr 10, 2024) |
| All-time low | $0.1624 (Nov 20, 2024) |
| 52-week high | $0.2397 |
| 52-week low | $0.2267 |
| Median price | $0.2441 |
| Average price | $0.2447 |
| Largest weekly change | -35.2% (Nov 20, 2024) |
| Weeks tracked | 308 |
| Tracking since | Nov 11, 2020 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 54% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
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Therapeutic class
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of DOXYCYCLINE MONO 100 MG CAP?
The current National Average Drug Acquisition Cost (NADAC) for DOXYCYCLINE MONO 100 MG CAP, manufactured by AvPAK, is $0.2267 per EA (NDC 50268028115), effective Sep 30, 2026.
How has the price of DOXYCYCLINE MONO 100 MG CAP changed over time?
Over the history we have for it, the NADAC for DOXYCYCLINE MONO 100 MG CAP has declined 15.6%. It has been tracked across 308 weekly CMS publications since Nov 11, 2020.
What are the highest and lowest recorded NADAC prices for DOXYCYCLINE MONO 100 MG CAP?
Since Nov 11, 2020, the NADAC for DOXYCYCLINE MONO 100 MG CAP has ranged from a low of $0.1624 (Nov 20, 2024) to a high of $0.2875 (Apr 10, 2024), with a median of $0.2441 per EA.
Are there cheaper alternatives to DOXYCYCLINE MONO 100 MG CAP?
Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DOXYCYCLINE HYCLATE 100 MG CAP, is $0.1049 per EA — about 54% below DOXYCYCLINE MONO 100 MG CAP.
Who manufactures DOXYCYCLINE MONO 100 MG CAP?
DOXYCYCLINE MONO 100 MG CAP (NDC 50268028115) is labeled by AvPAK, and CMS classifies it as a generic product.