Product Information
HYDROCHLOROTHIAZIDE 12.5 MG CP is a generic product labeled by AvPAK, priced at $0.0279 per EA under NDC 50268040415. Its NADAC has been published 172 times since May 10, 2023.
FDA first approved this application on Jan 14, 2019. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
12.5 mg/1
Manufacturer
AvPAKNDC
50268040415
Classification
Generic
Dosage Form
CAPSULE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
HYDROCHLOROTHIAZIDEApproval Type
Generic (ANDA)
FDA Application
ANDA203561FDA Approved
1/14/2019
TE Code
AB
On Market Since
12/8/2022
Pharmacological Classes
Price Statistics
The NADAC for HYDROCHLOROTHIAZIDE 12.5 MG CP has been published 172 times since May 10, 2023, and over the history we have for it it has declined 6.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0279 per EA |
|---|---|
| All-time high | $0.0341 (Jan 10, 2024) |
| All-time low | $0.0263 (Jul 17, 2024) |
| 52-week high | $0.0306 |
| 52-week low | $0.0279 |
| Median price | $0.0301 |
| Average price | $0.0303 |
| Largest weekly change | +21.9% (Aug 21, 2024) |
| Weeks tracked | 172 |
| Tracking since | May 10, 2023 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of HYDROCHLOROTHIAZIDE 12.5 MG CP?
The current National Average Drug Acquisition Cost (NADAC) for HYDROCHLOROTHIAZIDE 12.5 MG CP, manufactured by AvPAK, is $0.0279 per EA (NDC 50268040415), effective Aug 19, 2026.
How has the price of HYDROCHLOROTHIAZIDE 12.5 MG CP changed over time?
Over the history we have for it, the NADAC for HYDROCHLOROTHIAZIDE 12.5 MG CP has declined 6.9%. It has been tracked across 172 weekly CMS publications since May 10, 2023.
What are the highest and lowest recorded NADAC prices for HYDROCHLOROTHIAZIDE 12.5 MG CP?
Since May 10, 2023, the NADAC for HYDROCHLOROTHIAZIDE 12.5 MG CP has ranged from a low of $0.0263 (Jul 17, 2024) to a high of $0.0341 (Jan 10, 2024), with a median of $0.0301 per EA.
Are there cheaper alternatives to HYDROCHLOROTHIAZIDE 12.5 MG CP?
5 manufacturers publish a NADAC-priced product with the same active ingredient and strength as HYDROCHLOROTHIAZIDE 12.5 MG CP in a comparable dosage form, but none are currently priced below it.
Who manufactures HYDROCHLOROTHIAZIDE 12.5 MG CP?
HYDROCHLOROTHIAZIDE 12.5 MG CP (NDC 50268040415) is labeled by AvPAK, and CMS classifies it as a generic product.