Product Information

LETROZOLE 2.5 MG TABLET is a generic product labeled by AvPAK, priced at $0.1511 per EA under NDC 50268047615. Its NADAC has been published 348 times since Dec 25, 2019.

FDA first approved this application on Jun 3, 2011. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

LETROZOLE 2.5 MG TABLET

LETROZOLE
$0.1511per EA

Strength

2.5 mg/1

Manufacturer

AvPAK

NDC

50268047615

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

LETROZOLE

Approval Type

Generic (ANDA)

FDA Application

ANDA200161

FDA Approved

6/3/2011

TE Code

AB

On Market Since

10/2/2019

Pharmacological Classes

Aromatase Inhibitor
Aromatase Inhibitors

Price Statistics

The NADAC for LETROZOLE 2.5 MG TABLET has been published 348 times since Dec 25, 2019, and over the history we have for it it has risen 14.0%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1511 per EA
All-time high$0.1535 (Jul 15, 2026)
All-time low$0.1009 (Jun 21, 2023)
52-week high$0.1535
52-week low$0.1292
Median price$0.1406
Average price$0.1356
Largest weekly change+32.3% (Nov 22, 2023)
Weeks tracked348
Tracking sinceDec 25, 2019

Price History

1W

+0.8%

1M

+0.8%

3M

+0.7%

6M

+5.0%

1Y

+12.3%

3Y

+41.6%

5Y

+4.7%

All

+14.0%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of LETROZOLE 2.5 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for LETROZOLE 2.5 MG TABLET, manufactured by AvPAK, is $0.1511 per EA (NDC 50268047615), effective Aug 19, 2026.

How has the price of LETROZOLE 2.5 MG TABLET changed over time?

Over the history we have for it, the NADAC for LETROZOLE 2.5 MG TABLET has risen 14.0%. It has been tracked across 348 weekly CMS publications since Dec 25, 2019.

What are the highest and lowest recorded NADAC prices for LETROZOLE 2.5 MG TABLET?

Since Dec 25, 2019, the NADAC for LETROZOLE 2.5 MG TABLET has ranged from a low of $0.1009 (Jun 21, 2023) to a high of $0.1535 (Jul 15, 2026), with a median of $0.1406 per EA.

Are there cheaper alternatives to LETROZOLE 2.5 MG TABLET?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as LETROZOLE 2.5 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures LETROZOLE 2.5 MG TABLET?

LETROZOLE 2.5 MG TABLET (NDC 50268047615) is labeled by AvPAK, and CMS classifies it as a generic product.