Product Information
LETROZOLE 2.5 MG TABLET is a generic product labeled by AvPAK, priced at $0.1450 per EA under NDC 50268047615. Its NADAC has been published 354 times since Dec 25, 2019.
FDA first approved this application on Jun 3, 2011. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
2.5 mg/1
Manufacturer
AvPAKNDC
50268047615
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
LETROZOLEApproval Type
Generic (ANDA)
FDA Application
ANDA200161FDA Approved
6/3/2011
TE Code
AB
On Market Since
10/2/2019
Pharmacological Classes
Price Statistics
The NADAC for LETROZOLE 2.5 MG TABLET has been published 354 times since Dec 25, 2019, and over the history we have for it it has risen 9.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1450 per EA |
|---|---|
| All-time high | $0.1535 (Jul 15, 2026) |
| All-time low | $0.1009 (Jun 21, 2023) |
| 52-week high | $0.1535 |
| 52-week low | $0.1292 |
| Median price | $0.1407 |
| Average price | $0.1358 |
| Largest weekly change | +32.3% (Nov 22, 2023) |
| Weeks tracked | 354 |
| Tracking since | Dec 25, 2019 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
AvPAK manufacturer profile
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Drug market
LETROZOLE market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Aromatase Inhibitor class view
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Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of LETROZOLE 2.5 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for LETROZOLE 2.5 MG TABLET, manufactured by AvPAK, is $0.1450 per EA (NDC 50268047615), effective Sep 30, 2026.
How has the price of LETROZOLE 2.5 MG TABLET changed over time?
Over the history we have for it, the NADAC for LETROZOLE 2.5 MG TABLET has risen 9.3%. It has been tracked across 354 weekly CMS publications since Dec 25, 2019.
What are the highest and lowest recorded NADAC prices for LETROZOLE 2.5 MG TABLET?
Since Dec 25, 2019, the NADAC for LETROZOLE 2.5 MG TABLET has ranged from a low of $0.1009 (Jun 21, 2023) to a high of $0.1535 (Jul 15, 2026), with a median of $0.1407 per EA.
Are there cheaper alternatives to LETROZOLE 2.5 MG TABLET?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as LETROZOLE 2.5 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures LETROZOLE 2.5 MG TABLET?
LETROZOLE 2.5 MG TABLET (NDC 50268047615) is labeled by AvPAK, and CMS classifies it as a generic product.