Product Information
ONDANSETRON HCL 4 MG TABLET is a generic product labeled by AvPAK, priced at $0.0582 per EA under NDC 50268062115. Its NADAC has been published 464 times since Nov 15, 2017.
FDA first approved this application on Jul 31, 2007. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
4 mg/1
Manufacturer
AvPAKNDC
50268062115
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
ONDANSETRON HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA078539FDA Approved
7/31/2007
TE Code
AB
On Market Since
8/5/2016
Pharmacological Classes
Price Statistics
The NADAC for ONDANSETRON HCL 4 MG TABLET has been published 464 times since Nov 15, 2017, and over the history we have for it it has declined 48.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0582 per EA |
|---|---|
| All-time high | $0.1127 (Nov 15, 2017) |
| All-time low | $0.0555 (Jul 17, 2024) |
| 52-week high | $0.0691 |
| 52-week low | $0.0582 |
| Median price | $0.0707 |
| Average price | $0.0756 |
| Largest weekly change | +27.2% (Aug 21, 2024) |
| Weeks tracked | 464 |
| Tracking since | Nov 15, 2017 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
AvPAK manufacturer profile
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Drug market
Ondansetron Hydrochloride market comparison
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Therapeutic class
Serotonin-3 Receptor Antagonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of ONDANSETRON HCL 4 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for ONDANSETRON HCL 4 MG TABLET, manufactured by AvPAK, is $0.0582 per EA (NDC 50268062115), effective Sep 30, 2026.
How has the price of ONDANSETRON HCL 4 MG TABLET changed over time?
Over the history we have for it, the NADAC for ONDANSETRON HCL 4 MG TABLET has declined 48.3%. It has been tracked across 464 weekly CMS publications since Nov 15, 2017.
What are the highest and lowest recorded NADAC prices for ONDANSETRON HCL 4 MG TABLET?
Since Nov 15, 2017, the NADAC for ONDANSETRON HCL 4 MG TABLET has ranged from a low of $0.0555 (Jul 17, 2024) to a high of $0.1127 (Nov 15, 2017), with a median of $0.0707 per EA.
Are there cheaper alternatives to ONDANSETRON HCL 4 MG TABLET?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ONDANSETRON HCL 4 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures ONDANSETRON HCL 4 MG TABLET?
ONDANSETRON HCL 4 MG TABLET (NDC 50268062115) is labeled by AvPAK, and CMS classifies it as a generic product.