Product Information

RANOLAZINE ER 1,000 MG TABLET is a generic product labeled by AvPAK, priced at $0.2787 per EA under NDC 50268072313. Its NADAC has been published 172 times since May 10, 2023.

FDA first approved this application on Nov 30, 2020. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

RANOLAZINE ER 1,000 MG TABLET

Ranolazine
$0.2787per EA

Strength

1000 mg/1

Manufacturer

AvPAK

NDC

50268072313

Classification

Generic

Dosage Form

TABLET, FILM COATED, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

RANOLAZINE

Approval Type

Generic (ANDA)

FDA Application

ANDA209953

FDA Approved

11/30/2020

TE Code

AB

On Market Since

9/20/2022

Pharmacological Classes

Anti-anginal
Cytochrome P450 2D6 Inhibitors
Cytochrome P450 3A Inhibitors
Organic Cation Transporter 2 Inhibitors
P-Glycoprotein Inhibitors

Price Statistics

The NADAC for RANOLAZINE ER 1,000 MG TABLET has been published 172 times since May 10, 2023, and over the history we have for it it has declined 17.3%. The table below summarizes its recorded NADAC range and movement.

Current price$0.2787 per EA
All-time high$0.3710 (Jul 10, 2024)
All-time low$0.2725 (Apr 22, 2026)
52-week high$0.3159
52-week low$0.2725
Median price$0.3195
Average price$0.3168
Largest weekly change+14.7% (Jan 17, 2024)
Weeks tracked172
Tracking sinceMay 10, 2023

Price History

1W

-1.0%

1M

-1.0%

3M

-1.3%

6M

+1.1%

1Y

-11.8%

3Y

-14.8%

5Y

N/A

All

-17.3%

Generic Alternatives

The matcher finds 11 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 1% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of RANOLAZINE ER 1,000 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for RANOLAZINE ER 1,000 MG TABLET, manufactured by AvPAK, is $0.2787 per EA (NDC 50268072313), effective Aug 19, 2026.

How has the price of RANOLAZINE ER 1,000 MG TABLET changed over time?

Over the history we have for it, the NADAC for RANOLAZINE ER 1,000 MG TABLET has declined 17.3%. It has been tracked across 172 weekly CMS publications since May 10, 2023.

What are the highest and lowest recorded NADAC prices for RANOLAZINE ER 1,000 MG TABLET?

Since May 10, 2023, the NADAC for RANOLAZINE ER 1,000 MG TABLET has ranged from a low of $0.2725 (Apr 22, 2026) to a high of $0.3710 (Jul 10, 2024), with a median of $0.3195 per EA.

Are there cheaper alternatives to RANOLAZINE ER 1,000 MG TABLET?

Yes. 11 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, RANOLAZINE ER 1,000 MG TABLET, is $0.2757 per EA — about 1% below RANOLAZINE ER 1,000 MG TABLET.

Who manufactures RANOLAZINE ER 1,000 MG TABLET?

RANOLAZINE ER 1,000 MG TABLET (NDC 50268072313) is labeled by AvPAK, and CMS classifies it as a generic product.