Product Information
RANOLAZINE ER 1,000 MG TABLET is a generic product labeled by AvPAK, priced at $0.2743 per EA under NDC 50268072313. Its NADAC has been published 178 times since May 10, 2023.
FDA first approved this application on Nov 30, 2020. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
1000 mg/1
Manufacturer
AvPAKNDC
50268072313
Classification
Generic
Dosage Form
TABLET, FILM COATED, EXTENDED RELEASE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
RANOLAZINEApproval Type
Generic (ANDA)
FDA Application
ANDA209953FDA Approved
11/30/2020
TE Code
AB
On Market Since
9/20/2022
Pharmacological Classes
Price Statistics
The NADAC for RANOLAZINE ER 1,000 MG TABLET has been published 178 times since May 10, 2023, and over the history we have for it it has declined 18.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2743 per EA |
|---|---|
| All-time high | $0.3710 (Jul 10, 2024) |
| All-time low | $0.2725 (Apr 22, 2026) |
| 52-week high | $0.2954 |
| 52-week low | $0.2725 |
| Median price | $0.3194 |
| Average price | $0.3155 |
| Largest weekly change | +14.7% (Jan 17, 2024) |
| Weeks tracked | 178 |
| Tracking since | May 10, 2023 |
Generic Alternatives
The matcher finds 11 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
AvPAK manufacturer profile
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Drug market
Ranolazine market comparison
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Therapeutic class
Anti-anginal class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of RANOLAZINE ER 1,000 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for RANOLAZINE ER 1,000 MG TABLET, manufactured by AvPAK, is $0.2743 per EA (NDC 50268072313), effective Sep 30, 2026.
How has the price of RANOLAZINE ER 1,000 MG TABLET changed over time?
Over the history we have for it, the NADAC for RANOLAZINE ER 1,000 MG TABLET has declined 18.6%. It has been tracked across 178 weekly CMS publications since May 10, 2023.
What are the highest and lowest recorded NADAC prices for RANOLAZINE ER 1,000 MG TABLET?
Since May 10, 2023, the NADAC for RANOLAZINE ER 1,000 MG TABLET has ranged from a low of $0.2725 (Apr 22, 2026) to a high of $0.3710 (Jul 10, 2024), with a median of $0.3194 per EA.
Are there cheaper alternatives to RANOLAZINE ER 1,000 MG TABLET?
11 manufacturers publish a NADAC-priced product with the same active ingredient and strength as RANOLAZINE ER 1,000 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures RANOLAZINE ER 1,000 MG TABLET?
RANOLAZINE ER 1,000 MG TABLET (NDC 50268072313) is labeled by AvPAK, and CMS classifies it as a generic product.