Product Information
INVEGA TRINZA 546 MG/1.75 ML is a brand product labeled by Janssen Pharmaceuticals Inc., priced at $3993.6341 per ML under NDC 50458060801. Its NADAC has been published 542 times since May 18, 2016.
FDA first approved this application on May 18, 2015.
Strength
546 mg/1.75mL
Manufacturer
Janssen Pharmaceuticals Inc.NDC
50458060801
Classification
Brand
Dosage Form
INJECTION, SUSPENSION, EXTENDED RELEASE
Route
INTRAMUSCULAR
Effective Date
9/23/2026
Active Ingredients
PALIPERIDONE PALMITATEApproval Type
New Drug (NDA)
FDA Application
NDA207946FDA Approved
5/18/2015
On Market Since
5/19/2015
Pharmacological Classes
Price Statistics
The NADAC for INVEGA TRINZA 546 MG/1.75 ML has been published 542 times since May 18, 2016, and over the history we have for it it has risen 73.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $3993.6341 per ML |
|---|---|
| All-time high | $4011.1138 (Jul 15, 2026) |
| All-time low | $2302.2983 (May 18, 2016) |
| 52-week high | $4011.1138 |
| 52-week low | $3899.0431 |
| Median price | $3233.8926 |
| Average price | $3258.0451 |
| Largest weekly change | +6.9% (Jan 16, 2019) |
| Weeks tracked | 542 |
| Tracking since | May 18, 2016 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the paliperidone palmitate market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Janssen Pharmaceuticals Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
paliperidone palmitate market comparison
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Therapeutic class
Atypical Antipsychotic class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of INVEGA TRINZA 546 MG/1.75 ML?
The current National Average Drug Acquisition Cost (NADAC) for INVEGA TRINZA 546 MG/1.75 ML, manufactured by Janssen Pharmaceuticals Inc., is $3993.6341 per ML (NDC 50458060801), effective Sep 30, 2026.
How has the price of INVEGA TRINZA 546 MG/1.75 ML changed over time?
Over the history we have for it, the NADAC for INVEGA TRINZA 546 MG/1.75 ML has risen 73.5%. It has been tracked across 542 weekly CMS publications since May 18, 2016.
What are the highest and lowest recorded NADAC prices for INVEGA TRINZA 546 MG/1.75 ML?
Since May 18, 2016, the NADAC for INVEGA TRINZA 546 MG/1.75 ML has ranged from a low of $2302.2983 (May 18, 2016) to a high of $4011.1138 (Jul 15, 2026), with a median of $3233.8926 per ML.
Are there cheaper alternatives to INVEGA TRINZA 546 MG/1.75 ML?
No other NADAC-published product currently shares the active ingredient and strength of INVEGA TRINZA 546 MG/1.75 ML in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures INVEGA TRINZA 546 MG/1.75 ML?
INVEGA TRINZA 546 MG/1.75 ML (NDC 50458060801) is labeled by Janssen Pharmaceuticals Inc., and CMS classifies it as a brand product.