Product Information

INVEGA TRINZA 546 MG/1.75 ML is a brand product labeled by Janssen Pharmaceuticals Inc., priced at $3993.2087 per ML under NDC 50458060801. Its NADAC has been published 536 times since May 18, 2016.

FDA first approved this application on May 18, 2015.

INVEGA TRINZA 546 MG/1.75 ML

paliperidone palmitate
$3993.2087per ML

Strength

546 mg/1.75mL

NDC

50458060801

Classification

Brand

Dosage Form

INJECTION, SUSPENSION, EXTENDED RELEASE

Route

INTRAMUSCULAR

Effective Date

8/19/2026

Active Ingredients

PALIPERIDONE PALMITATE

Approval Type

New Drug (NDA)

FDA Application

NDA207946

FDA Approved

5/18/2015

On Market Since

5/19/2015

Pharmacological Classes

Price Statistics

The NADAC for INVEGA TRINZA 546 MG/1.75 ML has been published 536 times since May 18, 2016, and over the history we have for it it has risen 73.4%. The table below summarizes its recorded NADAC range and movement.

Current price$3993.2087 per ML
All-time high$4011.1138 (Jul 15, 2026)
All-time low$2302.2983 (May 18, 2016)
52-week high$4011.1138
52-week low$3899.0431
Median price$3233.8926
Average price$3249.8140
Largest weekly change+6.9% (Jan 16, 2019)
Weeks tracked536
Tracking sinceMay 18, 2016

Price History

1W

+0.2%

1M

+0.2%

3M

-0.4%

6M

-0.1%

1Y

+2.3%

3Y

+9.1%

5Y

+23.5%

All

+73.4%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the paliperidone palmitate market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Frequently asked questions

What is the NADAC price of INVEGA TRINZA 546 MG/1.75 ML?

The current National Average Drug Acquisition Cost (NADAC) for INVEGA TRINZA 546 MG/1.75 ML, manufactured by Janssen Pharmaceuticals Inc., is $3993.2087 per ML (NDC 50458060801), effective Aug 19, 2026.

How has the price of INVEGA TRINZA 546 MG/1.75 ML changed over time?

Over the history we have for it, the NADAC for INVEGA TRINZA 546 MG/1.75 ML has risen 73.4%. It has been tracked across 536 weekly CMS publications since May 18, 2016.

What are the highest and lowest recorded NADAC prices for INVEGA TRINZA 546 MG/1.75 ML?

Since May 18, 2016, the NADAC for INVEGA TRINZA 546 MG/1.75 ML has ranged from a low of $2302.2983 (May 18, 2016) to a high of $4011.1138 (Jul 15, 2026), with a median of $3233.8926 per ML.

Are there cheaper alternatives to INVEGA TRINZA 546 MG/1.75 ML?

No other NADAC-published product currently shares the active ingredient and strength of INVEGA TRINZA 546 MG/1.75 ML in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures INVEGA TRINZA 546 MG/1.75 ML?

INVEGA TRINZA 546 MG/1.75 ML (NDC 50458060801) is labeled by Janssen Pharmaceuticals Inc., and CMS classifies it as a brand product.