Product Information
TOPAMAX 50 MG TABLET is a brand product labeled by Janssen Pharmaceuticals Inc., priced at $13.1595 per EA under NDC 50458064065. Its NADAC has been published 644 times since Nov 28, 2013.
Strength
50 mg/1
Manufacturer
Janssen Pharmaceuticals Inc.NDC
50458064065
Classification
Brand
Dosage Form
TABLET, COATED
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
TOPIRAMATEApproval Type
New Drug (NDA)
FDA Application
NDA020505On Market Since
1/1/1997
Pharmacological Classes
Price Statistics
The NADAC for TOPAMAX 50 MG TABLET has been published 644 times since Nov 28, 2013, and over the history we have for it it has risen 89.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $13.1595 per EA |
|---|---|
| All-time high | $13.1595 (Jun 24, 2026) |
| All-time low | $6.9386 (Nov 28, 2013) |
| 52-week high | $13.1595 |
| 52-week low | $12.7213 |
| Median price | $11.7383 |
| Average price | $10.9867 |
| Largest weekly change | +9.9% (Jan 13, 2016) |
| Weeks tracked | 644 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 6 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 6 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 100% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of TOPAMAX 50 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for TOPAMAX 50 MG TABLET, manufactured by Janssen Pharmaceuticals Inc., is $13.1595 per EA (NDC 50458064065), effective Jun 24, 2026.
How has the price of TOPAMAX 50 MG TABLET changed over time?
Over the history we have for it, the NADAC for TOPAMAX 50 MG TABLET has risen 89.7%. It has been tracked across 644 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for TOPAMAX 50 MG TABLET?
Since Nov 28, 2013, the NADAC for TOPAMAX 50 MG TABLET has ranged from a low of $6.9386 (Nov 28, 2013) to a high of $13.1595 (Jun 24, 2026), with a median of $11.7383 per EA.
Are there cheaper alternatives to TOPAMAX 50 MG TABLET?
Yes. 6 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, TOPIRAMATE 50 MG TABLET, is $0.0345 per EA — about 100% below TOPAMAX 50 MG TABLET.
Who manufactures TOPAMAX 50 MG TABLET?
TOPAMAX 50 MG TABLET (NDC 50458064065) is labeled by Janssen Pharmaceuticals Inc., and CMS classifies it as a brand product.
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