Product Information
TOPAMAX 25 MG SPRINKLE CAP is a brand product labeled by Janssen Pharmaceuticals Inc., priced at $7.5400 per EA under NDC 50458064565. Its NADAC has been published 502 times since Nov 28, 2013.
FDA first approved this application on Oct 26, 1998. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25 mg/1
Manufacturer
Janssen Pharmaceuticals Inc.NDC
50458064565
Classification
Brand
Dosage Form
CAPSULE, COATED PELLETS
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
TOPIRAMATEApproval Type
New Drug (NDA)
FDA Application
NDA020844FDA Approved
10/26/1998
TE Code
AB
On Market Since
11/1/1998
Pharmacological Classes
Price Statistics
The NADAC for TOPAMAX 25 MG SPRINKLE CAP has been published 502 times since Nov 28, 2013, and over the history we have for it it has risen 85.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $7.5400 per EA |
|---|---|
| All-time high | $7.5693 (Sep 16, 2026) |
| All-time low | $4.0609 (Nov 28, 2013) |
| 52-week high | $7.5693 |
| 52-week low | $7.3249 |
| Median price | $6.3310 |
| Average price | $6.1485 |
| Largest weekly change | +9.9% (Jan 15, 2014) |
| Weeks tracked | 502 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 70% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Janssen Pharmaceuticals Inc. manufacturer profile
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Drug market
topiramate market comparison
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
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Frequently asked questions
What is the NADAC price of TOPAMAX 25 MG SPRINKLE CAP?
The current National Average Drug Acquisition Cost (NADAC) for TOPAMAX 25 MG SPRINKLE CAP, manufactured by Janssen Pharmaceuticals Inc., is $7.5400 per EA (NDC 50458064565), effective Sep 30, 2026.
How has the price of TOPAMAX 25 MG SPRINKLE CAP changed over time?
Over the history we have for it, the NADAC for TOPAMAX 25 MG SPRINKLE CAP has risen 85.7%. It has been tracked across 502 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for TOPAMAX 25 MG SPRINKLE CAP?
Since Nov 28, 2013, the NADAC for TOPAMAX 25 MG SPRINKLE CAP has ranged from a low of $4.0609 (Nov 28, 2013) to a high of $7.5693 (Sep 16, 2026), with a median of $6.3310 per EA.
Are there cheaper alternatives to TOPAMAX 25 MG SPRINKLE CAP?
Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, TOPIRAMATE ER 25 MG SPRINKL CAP, is $2.2543 per EA — about 70% below TOPAMAX 25 MG SPRINKLE CAP.
Who manufactures TOPAMAX 25 MG SPRINKLE CAP?
TOPAMAX 25 MG SPRINKLE CAP (NDC 50458064565) is labeled by Janssen Pharmaceuticals Inc., and CMS classifies it as a brand product.