Product Information
KEPPRA XR 500 MG TABLET is a brand product labeled by UCB, Inc., priced at $9.0308 per EA under NDC 50474059866. Its NADAC has been published 665 times since Nov 28, 2013.
FDA first approved this application on Sep 12, 2008. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The High Outlier badge above means this manufacturer's average price in the levetiracetam market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
500 mg/1
Manufacturer
UCB, Inc.NDC
50474059866
Classification
Brand
Dosage Form
TABLET, FILM COATED, EXTENDED RELEASE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
LEVETIRACETAMApproval Type
New Drug (NDA)
FDA Application
NDA022285FDA Approved
9/12/2008
TE Code
AB
On Market Since
9/24/2008
Pharmacological Classes
Price Statistics
The NADAC for KEPPRA XR 500 MG TABLET has been published 665 times since Nov 28, 2013, and over the history we have for it it has risen 78.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $9.0308 per EA |
|---|---|
| All-time high | $9.0505 (Jun 10, 2026) |
| All-time low | $5.0743 (Nov 28, 2013) |
| 52-week high | $9.0505 |
| 52-week low | $8.7844 |
| Median price | $7.0634 |
| Average price | $7.1961 |
| Largest weekly change | +9.9% (Jan 8, 2014) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 99% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of KEPPRA XR 500 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for KEPPRA XR 500 MG TABLET, manufactured by UCB, Inc., is $9.0308 per EA (NDC 50474059866), effective Aug 19, 2026.
How has the price of KEPPRA XR 500 MG TABLET changed over time?
Over the history we have for it, the NADAC for KEPPRA XR 500 MG TABLET has risen 78.0%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for KEPPRA XR 500 MG TABLET?
Since Nov 28, 2013, the NADAC for KEPPRA XR 500 MG TABLET has ranged from a low of $5.0743 (Nov 28, 2013) to a high of $9.0505 (Jun 10, 2026), with a median of $7.0634 per EA.
Are there cheaper alternatives to KEPPRA XR 500 MG TABLET?
Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, LEVETIRACETAM 500 MG TABLET, is $0.0739 per EA — about 99% below KEPPRA XR 500 MG TABLET.
Who manufactures KEPPRA XR 500 MG TABLET?
KEPPRA XR 500 MG TABLET (NDC 50474059866) is labeled by UCB, Inc., and CMS classifies it as a brand product.