Historical record - last NADAC effective date: 11/16/2022
Product Information
ISOSORBIDE-HYDRALAZINE 20-37.5 MG TABLET is a generic product labeled by Ingenus Pharmaceuticals LLC, priced at $1.5764 per EA under NDC 50742024618. Its NADAC has been published 14 times since Sep 21, 2022.
FDA first approved this application on Apr 6, 2022. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
ISOSORBIDE-HYDRALAZINE 20-37.5 MG TABLET
Isosorbide dinitrate and hydralazine hydrochlorideStrength
37.5; 20 mg/1; mg/1
Manufacturer
Ingenus Pharmaceuticals LLCNDC
50742024618
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
11/16/2022
Active Ingredients
HYDRALAZINE HYDROCHLORIDE; ISOSORBIDE DINITRATEApproval Type
Generic (ANDA)
FDA Application
ANDA215586FDA Approved
4/6/2022
TE Code
AB
On Market Since
4/12/2022
Pharmacological Classes
Price Statistics
The NADAC for ISOSORBIDE-HYDRALAZINE 20-37.5 MG TABLET has been published 14 times since Sep 21, 2022, and over the history we have for it it has risen 14.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.5764 per EA |
|---|---|
| All-time high | $1.5764 (Dec 21, 2022) |
| All-time low | $1.3757 (Sep 21, 2022) |
| Median price | $1.3757 |
| Average price | $1.4617 |
| Largest weekly change | +14.6% (Nov 16, 2022) |
| Weeks tracked | 14 |
| Tracking since | Sep 21, 2022 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
N/A
3Y
N/A
5Y
N/A
All
+14.6%
Last surveyed Dec 21, 2022 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 55% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Ingenus Pharmaceuticals LLC manufacturer profile
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Drug market
Isosorbide dinitrate and hydralazine hydrochloride market comparison
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Therapeutic class
Arteriolar Vasodilator class view
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Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of ISOSORBIDE-HYDRALAZINE 20-37.5 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for ISOSORBIDE-HYDRALAZINE 20-37.5 MG TABLET, manufactured by Ingenus Pharmaceuticals LLC, is $1.5764 per EA (NDC 50742024618), effective Dec 21, 2022.
How has the price of ISOSORBIDE-HYDRALAZINE 20-37.5 MG TABLET changed over time?
Over the history we have for it, the NADAC for ISOSORBIDE-HYDRALAZINE 20-37.5 MG TABLET has risen 14.6%. It has been tracked across 14 weekly CMS publications since Sep 21, 2022.
What are the highest and lowest recorded NADAC prices for ISOSORBIDE-HYDRALAZINE 20-37.5 MG TABLET?
Since Sep 21, 2022, the NADAC for ISOSORBIDE-HYDRALAZINE 20-37.5 MG TABLET has ranged from a low of $1.3757 (Sep 21, 2022) to a high of $1.5764 (Dec 21, 2022), with a median of $1.3757 per EA.
Are there cheaper alternatives to ISOSORBIDE-HYDRALAZINE 20-37.5 MG TABLET?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ISOSORBIDE-HYDRALAZINE 20-37.5 MG TABLET, is $0.7138 per EA — about 55% below ISOSORBIDE-HYDRALAZINE 20-37.5 MG TABLET.
Who manufactures ISOSORBIDE-HYDRALAZINE 20-37.5 MG TABLET?
ISOSORBIDE-HYDRALAZINE 20-37.5 MG TABLET (NDC 50742024618) is labeled by Ingenus Pharmaceuticals LLC, and CMS classifies it as a generic product.