Product Information
POLY-HIST DM LIQUID is a generic product labeled by Poly Pharmaceuticals, Inc., priced at $0.1603 per ML under NDC 50991022016. Its NADAC has been published 330 times since Feb 17, 2016.
POLY-HIST DM LIQUID
Dextromethorphan Hydrobromide, Phenylephrine HCl and Thonzylamine HClStrength
10; 5; 25 mg/5mL; mg/5mL; mg/5mL
Manufacturer
Poly Pharmaceuticals, Inc.NDC
50991022016
Classification
Generic
Dosage Form
LIQUID
Route
ORAL
Effective Date
6/18/2025
Active Ingredients
DEXTROMETHORPHAN HYDROBROMIDE; PHENYLEPHRINE HYDROCHLORIDE; THONZYLAMINE HYDROCHLORIDEApproval Type
OTC MONOGRAPH DRUG
FDA Application
M012On Market Since
6/22/2013
Pharmacological Classes
Price Statistics
The NADAC for POLY-HIST DM LIQUID has been published 330 times since Feb 17, 2016, and over the history we have for it it has declined 2.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1603 per ML |
|---|---|
| All-time high | $0.1636 (May 11, 2016) |
| All-time low | $0.1580 (Jan 17, 2018) |
| 52-week high | $0.1603 |
| 52-week low | $0.1603 |
| Median price | $0.1607 |
| Average price | $0.1607 |
| Largest weekly change | +2.2% (Feb 21, 2018) |
| Weeks tracked | 330 |
| Tracking since | Feb 17, 2016 |
1W
N/A
1M
N/A
3M
N/A
6M
0.0%
1Y
0.0%
3Y
-0.9%
5Y
-0.9%
All
-2.1%
Last surveyed Jun 10, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Dextromethorphan Hydrobromide, Phenylephrine HCl and Thonzylamine HCl market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Poly Pharmaceuticals, Inc. manufacturer profile
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Drug market
Dextromethorphan Hydrobromide, Phenylephrine HCl and Thonzylamine HCl market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Sigma-1 Agonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of POLY-HIST DM LIQUID?
The current National Average Drug Acquisition Cost (NADAC) for POLY-HIST DM LIQUID, manufactured by Poly Pharmaceuticals, Inc., is $0.1603 per ML (NDC 50991022016), effective Jun 10, 2026.
How has the price of POLY-HIST DM LIQUID changed over time?
Over the history we have for it, the NADAC for POLY-HIST DM LIQUID has declined 2.1%. It has been tracked across 330 weekly CMS publications since Feb 17, 2016.
What are the highest and lowest recorded NADAC prices for POLY-HIST DM LIQUID?
Since Feb 17, 2016, the NADAC for POLY-HIST DM LIQUID has ranged from a low of $0.1580 (Jan 17, 2018) to a high of $0.1636 (May 11, 2016), with a median of $0.1607 per ML.
Are there cheaper alternatives to POLY-HIST DM LIQUID?
No other NADAC-published product currently shares the active ingredient and strength of POLY-HIST DM LIQUID in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures POLY-HIST DM LIQUID?
POLY-HIST DM LIQUID (NDC 50991022016) is labeled by Poly Pharmaceuticals, Inc., and CMS classifies it as a generic product.