Therapeutic Classes/alpha-1 Adrenergic Agonist

alpha-1 Adrenergic Agonist

188 drugs across 31 manufacturers|130 Generic,58 Brand

The alpha-1 Adrenergic Agonist class contains 188 NDCs from 31 manufacturers (130 generic, 58 brand), at an average NADAC of $0.55 per unit. Every drug, manufacturer, and price in this FDA-defined pharmacologic class is listed below.

Total Drugs

188

130G / 58B

Manufacturers

Avg $0.5528/unit

Avg 7d Change

-0.34%

Across 89 drugs with changes

7d Activity

41↑48↓99 flat

of 188 total drugs

Class Price Trend

Monthly average NADAC price per unit, split by generic and brand

Manufacturer Breakdown

31 manufacturers producing drugs in this therapeutic class(7 pricing outliers)

Strategic Sourcing Services LLC

Haleon US Holdings LLC

16 drugs

$0.2532

avg/unit

Chain Drug Marketing Association

16 drugs

$0.1135

avg/unit

Edwards Pharmaceuticals, Inc.

8 drugs

$0.1463

avg/unit

Poly Pharmaceuticals, Inc.

The Procter & Gamble Manufacturing Company

and 19 more manufacturers

Drug Portfolio

188 drugs total, 188 shown

Drug ↕	NDC	Price	7d Change ↕	Class	Market Outlier	Manufacturer ↕
PHENYLEPHRINE 2.5% EYE DROP Phenylephrine Hydrochloride	00065034905	$9.2005 per ML	-0.82%	Generic	—	Alcon Laboratories, Inc.
PHENYLEPHRINE 2.5% EYE DROP phenylephrine hydrochloride	65145014801	$9.2005 per ML	-0.82%	Generic	—	Caplin Steriles Limited
PHENYLEPHRINE 2.5% EYE DROP PHENYLEPHRINE HYDROCHLORIDE	69315032308	$9.2005 per ML	-0.82%	Generic	—	Leading Pharma, LLC
PHENYLEPHRINE 2.5% EYE DROP Phenylephrine Hydrochloride	70512086502	$9.2005 per ML	-0.82%	Generic	—	SOLA Pharmaceuticals LLC
PHENYLEPHRINE 2.5% EYE DROP Phenylephrine Hydrochloride	70756062925	$9.2005 per ML	-0.82%	Generic	—	Lifestar Pharma LLC
PHENYLEPHRINE 2.5% EYE DROP Phenylephrine Hydrochloride	72603052001	$9.2005 per ML	-0.82%	Generic	—	NorthStar Rx LLC
PHENYLEPHRINE 2.5% EYE DROP PHENYLEPHRINE HYDROCHLORIDE	75907012907	$9.2005 per ML	-0.82%	Generic	—	Dr. Reddy's Laboratories Inc.
PHENYLEPHRINE 10% EYE DROP phenylephrine hydrochloride	42702010305	$5.1315 per ML	-1.84%	Generic	—	Paragon BioTeck, Inc.
PHENYLEPHRINE 2.5% EYE DROP phenylephrine hydrochloride	42702010215	$1.0784 per ML	—	Generic	—	Paragon BioTeck, Inc.
THERAFLU MS SEVERE COLD PCKT ACETAMINOPHEN, DEXTROMETHORPHAN HBr, PHENYLEPHRINE HCl	00067642606	$0.9107 per EA	—	Brand OTC	High Outlier	Haleon US Holdings LLC
THERAFLU NT SEVERE CLD-CGH PKT ACETAMINOPHEN, DIPHENHYDRAMINE HCL, PHENYLEPHRINE HCL	00067791806	$0.9074 per EA	—	Brand OTC	—	Haleon US Holdings LLC
NOREL AD TABLET acetaminophen, chlorpheniramine maleate, and phenylephrine HCl	52747047570	$0.7451 per EA	—	Brand OTC	—	U.S. Pharmaceutical Corporation
MUCINEX FAST-MAX COLD-FLU CAP ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN, and PHENYLEPHRINE HYDROCHLORIDE	63824051808	$0.7369 per EA	—	Brand OTC	High Outlier	RB Health (US) LLC
MUCINEX FAST-MAX COLD-FLU CAP ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN, and PHENYLEPHRINE HYDROCHLORIDE	63824051816	$0.7369 per EA	—	Brand OTC	High Outlier	RB Health (US) LLC
MUCINEX FAST-MAX COLD-FLU-THRT Acetaminophen, Dextromethorphan hydrobromide, Guaifenesin, and Phenylephrine Hydrochloride	63824059116	$0.7369 per EA	—	Brand OTC	High Outlier	RB Health (US) LLC
MUCINEX SINUS-MAX PRESSURE-CGH ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN, and PHENYLEPHRINE HYDROCHLORIDE	63824069308	$0.7369 per EA	—	Brand OTC	High Outlier	RB Health (US) LLC
MUCINEX SINUS-MAX PRESSURE-CGH ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN, and PHENYLEPHRINE HYDROCHLORIDE	63824069316	$0.7369 per EA	—	Brand OTC	High Outlier	RB Health (US) LLC
MUCINEX FAST-MAX COLD-FLU CAP Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, and Phenylephrine Hydrochloride	72854012608	$0.7369 per EA	—	Brand OTC	High Outlier	RB Health (US) LLC
MUCINEX FAST-MAX COLD-FLU CAP Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, and Phenylephrine Hydrochloride	72854012616	$0.7369 per EA	—	Brand OTC	High Outlier	RB Health (US) LLC
MUCINEX FAST-MAX COLD-FLU-THRT Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, and Phenylephrine Hydrochloride	72854012716	$0.7369 per EA	—	Brand OTC	High Outlier	RB Health (US) LLC
MUCINEX SINUS-MAX PRESSURE-CGH Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, and Phenylephrine Hydrochloride	72854020208	$0.7369 per EA	—	Brand OTC	High Outlier	RB Health (US) LLC
MUCINEX SINUS-MAX PRESSURE-CGH Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, and Phenylephrine Hydrochloride	72854020216	$0.7369 per EA	—	Brand OTC	High Outlier	RB Health (US) LLC
DECONEX DMX 17.5-400-10 MG TAB Dextromethorphan Hydrobromide, Guaifenesin, Phenylephrine Hydrochloride	50991074001	$0.6717 per EA	—	Generic OTC	—	Poly Pharmaceuticals, Inc.
POLY HIST FORTE 10.5-10 MG TAB Doxylamine Succinate and Phenylephrine Hydrochloride	50991062601	$0.6637 per EA	-0.02%	Generic OTC	—	Poly Pharmaceuticals, Inc.
DECONEX IR 385-10 MG TABLET Guaifenesin and Phenylephrine HCl	50991073690	$0.6622 per EA	—	Generic OTC	—	Poly Pharmaceuticals, Inc.
ALAHIST PE 2-7.5 MG TABLET Dexbrompheniramine Maleate, Phenylephrine Hydrochloride	50991078890	$0.6579 per EA	-0.20%	Generic OTC	—	Poly Pharmaceuticals, Inc.
MUCINEX NIGHTSHFT SEVR CLD-FLU Acetaminophen, Dextromethorphan Hydrobromide, Phenylephrine Hydrochloride, and Triprolidine Hydrochloride	72854023420	$0.6171 per EA	—	Brand OTC	—	RB Health (US) LLC
MUCINEX NIGHTSHIFT SINUS CAPLT Acetaminophen, Dextromethorphan Hydrobromide, Phenylephrine Hydrochloride, and Triprolidine Hydrochloride	72854024020	$0.6171 per EA	—	Brand OTC	—	RB Health (US) LLC
MUCINEX FAST-MAX COLD-FLU CPLT Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, and Phenylephrine Hydrochloride	63824023720	$0.6118 per EA	—	Brand OTC	High Outlier	RB Health (US) LLC
MUCINEX FAST-MAX COLD-FLU CPLT Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, and Phenylephrine Hydrochloride	63824023721	$0.6118 per EA	—	Brand OTC	High Outlier	RB Health (US) LLC
MUCINEX SINUS-MAX PRESSURE-CGH Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, and Phenylephrine Hydrochloride	63824024220	$0.6118 per EA	—	Brand OTC	High Outlier	RB Health (US) LLC
MUCINEX FAST-MAX COLD-FLU CPLT Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, and Phenylephrine Hydrochloride	63824057504	$0.6118 per EA	—	Brand OTC	High Outlier	RB Health (US) LLC
MUCINEX FAST-MAX COLD-FLU CPLT Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, and Phenylephrine Hydrochloride	63824057521	$0.6118 per EA	—	Brand OTC	High Outlier	RB Health (US) LLC
MUCINEX FAST-MAX COLD-FLU CPLT Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, and Phenylephrine Hydrochloride	63824057544	$0.6118 per EA	—	Brand OTC	High Outlier	RB Health (US) LLC
MUCINEX FAST-MAX COLD-FLU CPLT Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, and Phenylephrine Hydrochloride	63824023744	$0.5594 per EA	—	Brand OTC	High Outlier	RB Health (US) LLC
MUCINEX SINUS-MAX SEVERE CPLT Acetaminophen, Guaifenesin, and Phenylephrine Hydrochloride	63824020144	$0.5291 per EA	—	Brand OTC	High Outlier	RB Health (US) LLC
QC NIGHT SEVERE COLD-COUGH PKT ACETAMINOPHEN, DIPHENHYDRAMINE, PHENYLEPHRINE	63868029106	$0.4817 per EA	—	Generic OTC	—	Chain Drug Marketing Association
ADVIL ALLERGY-CONGEST RLF TAB chlorpheniramine maleate, ibuprofen, and phenylephrine hydrochloride	00573019610	$0.4591 per EA	—	Brand OTC	—	Haleon US Holdings LLC
ED A-HIST DM TABLET CHLORPHENIRAMINE MALEATE, DEXTROMETHORPHAN HYDROBROMIDE, and PHENYLEPHRINE HYDROCHLORIDE	00485024001	$0.4312 per EA	+0.36%	Generic OTC	—	Edwards Pharmaceuticals, Inc.
PROMETHAZINE-PE-CODEINE SYRUP Promethazine, Phenylephrine, Codeine	65162069486	$0.3061 per ML	—	Generic	—	Amneal Pharmaceuticals LLC
GS HEMORRHOIDAL SUPPOSITORIES cocoa butter, phenylephrine HCl	00113027953	$0.2970 per EA	+1.93%	Generic OTC	—	L. Perrigo Company
HEMORRHOIDAL SUPPOSITORIES cocoa butter, phenylephrine HCl	00536118612	$0.2970 per EA	+1.93%	Generic OTC	—	Rugby Laboratories
GNP HEMORRHOIDAL SUPPOSITORIES Cocoa Butter, Phenylephrine HCl	46122077765	$0.2970 per EA	+1.93%	Generic OTC	—	AmerisourceBergen
HEMORRHOIDAL SUPPOSITORIES cocoa butter, phenylephrine HCl	70000022301	$0.2970 per EA	+1.93%	Generic OTC	—	Cardinal Health
FT HEMORRHOIDAL SUPPOSITORIES cocoa butter, phenylephrine HCl	70677129201	$0.2970 per EA	+1.93%	Generic OTC	—	Strategic Sourcing Services LLC
TUSNEL-DM PED 2.5-25-1.25 MG/ML Dextromethorphan HBr, Guaifenesin, Phenylephrine HCl	54859060601	$0.2846 per ML	-2.89%	Generic OTC	—	Llorens Pharmaceutical International Division
THERAFLU EXPRESSMAX DAY CAPLET acetaminophen, dextromethorphan HBr, phenylephrine HCl	00067813620	$0.2601 per EA	—	Brand OTC	High Outlier	Haleon US Holdings LLC
THERAFLU EXPRESSMAX NIGHT CPLT acetaminophen, diphenhydramine HCl, phenylephrine HCl	00067813720	$0.2583 per EA	—	Brand OTC	—	Haleon US Holdings LLC
RYMED TABLET DEXCHLORPHENIRAMINE MALEATE and PHENYLEPHRINE HYDROCHLORIDE	00485008001	$0.2240 per EA	—	Brand OTC	—	Edwards Pharmaceuticals, Inc.
ED-A-HIST 4 MG-10 MG TABLET CHLORPHENIRAMINE MALEATE and PHENYLEPHRINE HYDROCHLORIDE	00485025401	$0.2225 per EA	—	Generic OTC	—	Edwards Pharmaceuticals, Inc.
PROMETHAZINE-PE-CODEINE SYRUP Promethazine, Phenylephrine, Codeine	65162069490	$0.2220 per ML	—	Generic	—	Amneal Pharmaceuticals LLC
PREPARATION H CREAM glycerin, petrolatum, phenylephrine HCl, pramoxine HCl	00573286810	$0.2028 per GM	—	Brand OTC	—	Haleon US Holdings LLC
4 WAY 1% NASAL SPRAY Phenylephrine hydrochloride	00067208601	$0.1920 per ML	—	Brand OTC	—	Haleon US Holdings LLC
PREPARATION H OINTMENT mineral oil, petrolatum, phenylephrine HCl	00573287110	$0.1893 per GM	—	Brand OTC	High Outlier	Haleon US Holdings LLC
HEMORRHOIDAL SUPPOSITORIES cocoa butter, phenylephrine HCl	36800027953	$0.1840 per EA	—	Generic OTC	Low Outlier	Topco Associates LLC
PREPARATION H CREAM glycerin, petrolatum, phenylephrine HCl, pramoxine HCl	00573286820	$0.1822 per GM	—	Brand OTC	—	Haleon US Holdings LLC
PREPARATION H COOLING GEL phenylephrine hcl, witch hazel	00573284020	$0.1808 per GM	—	Brand OTC	—	Haleon US Holdings LLC
PROMETHAZINE-PE 6.25-5 MG/5 ML promethazine hydrochloride and phenylephrine hydrochloride	64950034516	$0.1632 per ML	—	Generic	—	Genus Lifesciences Inc.
PREPARATION H OINTMENT mineral oil, petrolatum, phenylephrine HCl	00573287120	$0.1621 per GM	—	Brand OTC	High Outlier	Haleon US Holdings LLC
POLY-HIST DM LIQUID Dextromethorphan Hydrobromide, Phenylephrine HCl and Thonzylamine HCl	50991022016	$0.1603 per ML	—	Generic OTC	—	Poly Pharmaceuticals, Inc.
GNP COLD-FLU SEVERE CAPLET ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN, and PHENYLEPHRINE HYDROCHLORIDE	46122041862	$0.1412 per EA	-1.42%	Generic OTC	—	AmerisourceBergen
SEVERE COLD-FLU CAPLET Acetaminophen, Dextromethorphan HBr, Guaifenesin, Phenylephrine HCl	70000052501	$0.1412 per EA	-1.42%	Generic OTC	—	Cardinal Health
DAYTIME SEVERE COLD-FLU CAPLET acetaminophen, dextromethorphan hydrobromide, guaifenesin, phenylephrine hydrochloride	70000063601	$0.1412 per EA	-1.42%	Generic OTC	—	Cardinal Health
FT DAYTIME SEVERE CLD-FLU CPLT acetaminophen, dextromethorphan hydrobromide, guaifenesin, phenylephrine hydrochloride	70677102701	$0.1412 per EA	-1.42%	Generic OTC	—	Strategic Sourcing Services LLC
QC MUCUS RLF COLD-FLU-THRT CPT ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN, and PHENYLEPHRINE HYDROCHLORIDE	83324010420	$0.1412 per EA	-1.42%	Generic OTC	—	Chain Drug Marketing Association
QC MUCUS RELIEF COLD-FLU CPLT ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN, and PHENYLEPHRINE HYDROCHLORIDE	83324010520	$0.1412 per EA	-1.42%	Generic OTC	—	Chain Drug Marketing Association
QC MUCUS RLF SINUS PAIN COUGH ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN, and PHENYLEPHRINE HYDROCHLORIDE	83324010620	$0.1412 per EA	-1.42%	Generic OTC	—	Chain Drug Marketing Association
QC COLD-FLU SEVERE CAPLET ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN, and PHENYLEPHRINE HYDROCHLORIDE	83324011124	$0.1412 per EA	-1.42%	Generic OTC	—	Chain Drug Marketing Association
DAYTIME COLD-FLU RELIEF SFTGL ACETAMINOHPEN, DEXTROMETHORPHAN HBr, PHENYLEPHRINE HCL	70000051501	$0.1331 per EA	—	Generic OTC	—	Cardinal Health
GNP HEMORRHOIDAL PAIN RLF CRM Hemorrhoidal	46122077637	$0.1301 per GM	-0.99%	Generic OTC	—	AmerisourceBergen
DAYTIME COLD-FLU RELIEF SFTGL ACETAMINOHPEN, DEXTROMETHORPHAN HBr, PHENYLEPHRINE HCL	00904699544	$0.1297 per EA	+1.49%	Generic OTC	—	Major Pharmaceuticals
DAY TIME COLD-FLU SOFTGEL Acetaminophen, Dextromethorphan HBr, Phenylephrine HCl	24385003662	$0.1297 per EA	+1.49%	Generic OTC	—	AmerisourceBergen
GNP SINUS SEVERE CAPLET ACETAMINOPHEN, GUAIFENESIN, and PHENYLEPHRINE HYDROCHLORIDE	46122041262	$0.1047 per EA	-2.49%	Generic OTC	—	AmerisourceBergen
GNP COLD HEAD CONGST SEVR CPLT ACETAMINOPHEN, GUAIFENESIN, and PHENYLEPHRINE HYDROCHLORIDE	46122041562	$0.1047 per EA	-2.49%	Generic OTC	—	AmerisourceBergen
GNP MUCUS RLF SINUS CONG PAIN ACETAMINOPHEN, GUAIFENESIN, and PHENYLEPHRINE HYDROCHLORIDE	46122071260	$0.1047 per EA	-2.49%	Generic OTC	—	AmerisourceBergen
SINUS CONGST-PAIN 325-200-5 MG ACETAMINOPHEN, GUAIFENESIN, and PHENYLEPHRINE HYDROCHLORIDE	70000008001	$0.1047 per EA	-2.49%	Generic OTC	—	Cardinal Health
HEAD CONGESTION-MUCUS CAPLET Acetaminophen, Guaifenesin, Phenylephrine HCl	70000008301	$0.1047 per EA	-2.49%	Generic OTC	—	Cardinal Health
FT SINUS SEVERE 325-200-5 MG ACETAMINOPHEN, GUAIFENESIN, and PHENYLEPHRINE HYDROCHLORIDE	70677100501	$0.1047 per EA	-2.49%	Generic OTC	—	Strategic Sourcing Services LLC
FT SINUS SEVERE 325-200-5 MG Acetaminophen, Guaifenesin, Phenylephrine HCl	70677125901	$0.1047 per EA	-2.49%	Generic OTC	—	Strategic Sourcing Services LLC
QC MUCUS RLF SINUS CONG PAIN ACETAMINOPHEN, GUAIFENESIN, and PHENYLEPHRINE HYDROCHLORIDE	83324010720	$0.1047 per EA	-2.49%	Generic OTC	—	Chain Drug Marketing Association
QC HEAD CONGEST-MUCUS PE CPLT ACETAMINOPHEN, GUAIFENESIN, and PHENYLEPHRINE HYDROCHLORIDE	83324011224	$0.1047 per EA	-2.49%	Generic OTC	—	Chain Drug Marketing Association
QC COLD HEAD CONGST SEVR CPLT ACETAMINOPHEN, GUAIFENESIN, and PHENYLEPHRINE HYDROCHLORIDE	83324011424	$0.1047 per EA	-2.49%	Generic OTC	—	Chain Drug Marketing Association
QC SINUS SEVERE 325-200-5 MG ACETAMINOPHEN, GUAIFENESIN, and PHENYLEPHRINE HYDROCHLORIDE	83324011524	$0.1047 per EA	-2.49%	Generic OTC	—	Chain Drug Marketing Association
VANACOF DM 18-200-10 MG/15 ML DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN, and PHENYLEPHRINE HYDROCHLORIDE	58809055508	$0.0975 per ML	—	Brand OTC	—	GM Pharmaceuticals, INC
MAPAP COLD FORMULA CAPLET Acetaminophen, Dextromethorphan HBr, Phenylephrine HCl	00904578624	$0.0945 per EA	-0.86%	Generic OTC	—	Major Pharmaceuticals
GNP COLD MAX DAYTIME CAPLET ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, and PHENYLEPHRINE HYDROCHLORIDE	46122041062	$0.0945 per EA	-0.86%	Generic OTC	—	AmerisourceBergen
CHEST CONG RLF PE 400-10 MG TB Guaifenesin/phenylephrine	00536130908	$0.0903 per EA	+1.34%	Generic OTC	—	Rugby Laboratories
GNP MUCUS RELIEF PE 400-10 MG Guaifenesin/phenylephrine	46122070071	$0.0903 per EA	+1.34%	Generic OTC	—	AmerisourceBergen
MUCUS RELIEF PE TABLET Guaifenesin, Phenylephrine HCl	70000014101	$0.0903 per EA	+1.34%	Generic OTC	—	Cardinal Health
FT CHEST CONG RLF PE 400-10 MG Guaifenesin/phenylephrine	70677105601	$0.0903 per EA	+1.34%	Generic OTC	—	Strategic Sourcing Services LLC
GNP ALLERGY MULTI-SYMPTOM CPLT ACETAMINOPHEN, CHLORPHENIRAMINE MALEATE, and PHENYLEPHRINE HYDROCHLORIDE	46122066062	$0.0882 per EA	-0.68%	Generic OTC	—	AmerisourceBergen
ALLERGY MULTI-SYMPTOM CAPLET Acetaminophen, Chlorpheniramine Maleate, Phenylephrine HCl	70000021101	$0.0882 per EA	-0.68%	Generic OTC	—	Cardinal Health
FT ALLERGY MULTI-SYMPTOM CPLT ACETAMINOPHEN, CHLORPHENIRAMINE MALEATE, and PHENYLEPHRINE HYDROCHLORIDE	70677100401	$0.0882 per EA	-0.68%	Generic OTC	—	Strategic Sourcing Services LLC
QC ALLERGY MULTI-SYMPTOM CPLT ACETAMINOPHEN, CHLORPHENIRAMINE MALEATE, and PHENYLEPHRINE HYDROCHLORIDE	83324008624	$0.0882 per EA	-0.68%	Generic OTC	—	Chain Drug Marketing Association
SINUS CONGESTION-PAIN CAPLET Acetaminophen, Phenylephrine HCl	00536128935	$0.0851 per EA	+0.28%	Generic OTC	—	Rugby Laboratories
GNP SINUS PRESSURE-PAIN CAPLET Acetaminophen, Phenylephrine HCl	46122044362	$0.0851 per EA	+0.28%	Generic OTC	—	AmerisourceBergen
GNP SINUS-HEADACHE CAPLET ACETAMINOPHEN and PHENYLEPHRINE HYDROCHLORIDE	46122065862	$0.0851 per EA	+0.28%	Generic OTC	—	AmerisourceBergen
SINUS PRESSURE-PAIN CAPLET Acetaminophen, Phenylephrine HCl	70000016101	$0.0851 per EA	+0.28%	Generic OTC	—	Cardinal Health
SINUS-HEADACHE 5-325 MG CAPLET Acetaminophen and Phenylephrine HCl	70000056801	$0.0851 per EA	+0.28%	Generic OTC	—	Cardinal Health
QC SINUS-HEADACHE CAPLET ACETAMINOPHEN and PHENYLEPHRINE HYDROCHLORIDE	83324009424	$0.0851 per EA	+0.28%	Generic OTC	—	Chain Drug Marketing Association
HEMORRHOIDAL CREAM Glycerin, Phenylephrine Hydrochloride, Pramoxine Hydrochloride, White Petrolatum	70000042501	$0.0845 per GM	+0.66%	Generic OTC	—	Cardinal Health
GNP NASAL FOUR 1% NASAL SPRAY Phenylephrine hydrochloride	46122068903	$0.0842 per ML	—	Generic OTC	—	AmerisourceBergen
CHEST CONG RLF PE 400-10 MG TB Guaifenesin/phenylephrine	00536130907	$0.0786 per EA	—	Generic OTC	—	Rugby Laboratories
GS CHILDREN'S COLD-COUGH SOLN Brompheniramine maleate, Dextromethorphan HBr, Phenylephrine HCl	00113098726	$0.0750 per ML	+0.13%	Generic OTC	—	L. Perrigo Company
RYNEX DM LIQUID Brompheniramine Maleate, Dextromethorphan Hydrobromide, Phenylephrine Hydrochloride	00485020404	$0.0750 per ML	+0.13%	Generic OTC	—	Edwards Pharmaceuticals, Inc.
DIMAPHEN DM ELIXIR Brompheniramine maleate, Dextromethorphan HBr, Phenylephrine HCl	00904646320	$0.0750 per ML	+0.13%	Generic OTC	—	Major Pharmaceuticals
COLD-COUGH ELIXIR Brompheniramine maleate, Dextromethorphan HBr, Phenylephrine HCl	24385051926	$0.0750 per ML	+0.13%	Generic OTC	—	AmerisourceBergen
CHILDREN'S COLD-COUGH LIQUID Brompheniramine maleate, Dextromethorphan, Phenylephrine HCl	70000063101	$0.0750 per ML	+0.13%	Generic OTC	—	Cardinal Health
LOHIST-DM SYRUP Brompheniramine Maleate, Dextromethorphan Hydrobromide and Phenylephrine Hydrochloride	68047012916	$0.0746 per ML	+0.51%	Generic OTC	—	Larken Laboratories, Inc.
HISTEX-DM SYRUP DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE HYDROCHLORIDE, and TRIPROLIDINE HYDROCHLORIDE	28595080416	$0.0739 per ML	—	Generic OTC	—	Allegis Pharmaceuticals, LLC
GS NASAL FOUR 1% NASAL SPRAY Phenylephrine hydrochloride	00113064810	$0.0730 per ML	-6.59%	Generic OTC	—	L. Perrigo Company
CHILD MUCINEX MS COLD-THROAT Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, and Phenylephrine Hydrochloride	63824095217	$0.0713 per ML	—	Brand OTC	High Outlier	RB Health (US) LLC
CHILD MUCINEX COLD-FLU LIQUID Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, and Phenylephrine Hydrochloride	63824095404	$0.0713 per ML	—	Brand OTC	High Outlier	RB Health (US) LLC
CHILD MUCINEX FREEFROM DY COLD Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, and Phenylephrine Hydrochloride	63824095864	$0.0713 per ML	—	Brand OTC	High Outlier	RB Health (US) LLC
CHILD MUCINEX STUFFY NOSE-CHST Guaifenesin and Phenylephrine Hydrochloride	63824095107	$0.0710 per ML	—	Brand OTC	—	RB Health (US) LLC
CHILD MUCINEX MULTI-SYMPTOM LQ Dextromethorphan Hydrobromide, Guaifenesin, and Phenylephrine Hydrochloride	63824094901	$0.0704 per ML	—	Brand OTC	—	RB Health (US) LLC
CHILDREN'S MUCINEX FREEFROM LQ DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN, and PHENYLEPHRINE HYDROCHLORIDE	63824095664	$0.0704 per ML	—	Brand OTC	—	RB Health (US) LLC
DM-GUAIF-PE 18-200-10 MG/15 ML DEXTROMETHORPHAN HYDROBROMIDE, Guaifenesin, and PHENYLEPHRINE HYDROCHLORIDE	69367018408	$0.0700 per ML	+0.94%	Generic OTC	—	Westminster Pharmaceuticals LLC
SM CHEST CONG RELIEF PE CAPLET Guaifenesin/phenylephrine	49348077409	$0.0697 per EA	—	Generic OTC	—	Strategic Sourcing Services LLC
SINUS RELIEF 1% NASAL SPRAY Phenylephrine Hydrochloride	70000013201	$0.0695 per ML	+0.55%	Generic OTC	—	Cardinal Health
QC NASAL SPRAY 1% Phenylephrine Hydrochloride	83324021501	$0.0695 per ML	+0.55%	Generic OTC	—	Chain Drug Marketing Association
ED-A-HIST DM LIQUID DEXTROMETHORPHAN HYDROBROMIDE, CHLORPHENIRAMINE MALEATE, and PHENYLEPHRINE HYDROCHLORIDE	00485017116	$0.0673 per ML	-0.06%	Generic OTC	—	Edwards Pharmaceuticals, Inc.
NOHIST-DM LIQUID Chlorpheniramine Maleate, Dextromethorphan Hydrobromide and Phenylephrine Hydrochloride	68047018616	$0.0673 per ML	-0.06%	Generic OTC	—	Larken Laboratories, Inc.
NASAL SPRAY 1% Phenylephrine hydrochloride	46122014903	$0.0650 per ML	—	Generic OTC	—	AmerisourceBergen
FT CHILD COLD-COUGH RELIEF DM Brompheniramine maleate, Dextromethorphan HBr, Phenylephrine HCl	70677104401	$0.0630 per ML	—	Generic OTC	—	Strategic Sourcing Services LLC
NASAL FOUR 1% NASAL SPRAY Phenylephrine hydrochloride	36800064810	$0.0623 per ML	—	Generic OTC	—	Topco Associates LLC
MUCINEX NIGHTSHIFT SINUS LIQ Acetaminophen, Dextromethorphan Hydrobromide, Phenylephrine Hydrochloride, and Triprolidine Hydrochloride	63824026966	$0.0623 per ML	—	Brand OTC	—	RB Health (US) LLC
MUCINEX NIGHTSHFT SEVR CLD-FLU ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE HYDROCHLORIDE, and TRIPROLIDINE HYDROCHLORIDE	63824050466	$0.0623 per ML	—	Brand OTC	—	RB Health (US) LLC
POLYTUSSIN DM 7.5-5-12.5 MG/5 ML Dextromethorphan HBr, Phenylephrine HCl, Pyrilamine Maleate	50991013216	$0.0623 per ML	—	Generic OTC	—	Poly Pharmaceuticals, Inc.
MUCINEX COLD-FLU-SORETHROAT LQ acetaminophen, dextromethorphan hydrobromide, guaifenesin, and phenylephrine hydrochloride	63824001566	$0.0621 per ML	—	Brand OTC	High Outlier	RB Health (US) LLC
MUCINEX FAST-MAX COLD-FLU LIQ ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN, and PHENYLEPHRINE HYDROCHLORIDE	63824052703	$0.0621 per ML	—	Brand OTC	High Outlier	RB Health (US) LLC
MUCINEX FAST-MAX COLD-FLU LIQ acetaminophen, dextromethorphan hydrobromide, guaifenesin, phenylephrine hydrochloride	63824054866	$0.0621 per ML	—	Brand OTC	—	RB Health (US) LLC
MUCINEX FAST-MAX COLD-FLU LIQ acetaminophen, dextromethorphan hydrobromide, guaifenesin, and phenylephrine hydrochloride	72854013866	$0.0621 per ML	—	Brand OTC	High Outlier	RB Health (US) LLC
MUCINEX FAST-MAX CONGEST-COUGH dextromethorphan hydrobromide, guaifenesin, and phenylephrine hydrochloride	63824054066	$0.0615 per ML	—	Brand OTC	—	RB Health (US) LLC
ALAHIST DM 10-12.5-5 MG/5 ML LQ Dextromethorphan HBr, Pheniramine Maleate, Phenylephrine HCl	50991044416	$0.0614 per ML	—	Generic OTC	—	Poly Pharmaceuticals, Inc.
GS HEMORRHOIDAL OINTMENT mineral oil, petrolatum, phenylephrine HCl	00113018816	$0.0544 per GM	+2.89%	Generic OTC	—	L. Perrigo Company
HEMORRHOIDAL OINTMENT Mineral Oil, Petrolatum, Phenylephrine HCI	00536128806	$0.0544 per GM	+2.89%	Generic OTC	—	Rugby
HEMORRHOIDAL OINTMENT mineral oil, petrolatum, phenylephrine HCl	45802018816	$0.0544 per GM	+2.89%	Generic OTC	—	Padagis Israel Pharmaceuticals Ltd
GNP HEMORRHOIDAL OINTMENT Mineral oil, Petrolatum, Phenylephrine, HCL	46122067746	$0.0544 per GM	+2.89%	Generic OTC	—	AmerisourceBergen
HEMORRHOIDAL OINTMENT Mineral Oil, Petrolatum, Phenylephrine HCI	70000004601	$0.0544 per GM	+2.89%	Generic OTC	—	Cardinal Health
FT HEMORRHOIDAL OINTMENT mineral oil, petrolatum, phenylephrine HCl	70677110801	$0.0544 per GM	+2.89%	Generic OTC	—	Strategic Sourcing Services LLC
ED A-HIST LIQUID Chlorpheniramine/Phenylephrine	00485015516	$0.0530 per ML	—	Generic OTC	—	Edwards Pharmaceuticals, Inc.
RYNEX DM LIQUID Brompheniramine Maleate, Dextromethorphan Hydrobromide, Phenylephrine Hydrochloride	00485020416	$0.0514 per ML	-1.17%	Generic OTC	—	Edwards Pharmaceuticals, Inc.
ENDACOF-DM LIQUID Brompheniramine Maleate, Dextromethorphan Hydrobromide and Phenylephrine Hydrochloride	68047014316	$0.0514 per ML	-1.17%	Generic OTC	—	Larken Laboratories, Inc.
NASAL DECONGESTANT PE 10 MG TB Phenylephrine HCl	70000012601	$0.0506 per EA	—	Generic OTC	—	Cardinal Health
NASAL DECONGESTANT PE 10 MG TB Phenylephrine HCl	70000012602	$0.0500 per EA	—	Generic OTC	—	Cardinal Health
FT NASAL DECONG PE 10 MG TAB Phenylephrine HCl	70677115201	$0.0498 per EA	-2.14%	Generic OTC	—	Strategic Sourcing Services LLC
FT NASAL DECONG PE 10 MG TAB Phenylephrine HCl	70677115202	$0.0498 per EA	-2.14%	Generic OTC	—	Strategic Sourcing Services LLC
QC SINUS CONGEST PE 10 MG TAB Phenylephrine HCl	83324007336	$0.0498 per EA	-2.14%	Generic OTC	—	Chain Drug Marketing Association
HEMORRHOIDAL CREAM glycerin, phenylephrine HCl, pramoxine HCl, white petrolatum	36800094424	$0.0469 per GM	—	Generic OTC	—	Topco Associates LLC
CHILD'S MULTI-SYMPTOM COLD LIQ Dextromethorphan HBr, guaifenesin, Phenylephrine HCl	70000062901	$0.0468 per ML	—	Generic OTC	—	Cardinal Health
RYNEX PE LIQUID BROMPHENIRAMINE MALEATE and Phenylephrine HCL	00485020216	$0.0463 per ML	+0.35%	Generic OTC	—	Edwards Pharmaceuticals, Inc.
WESTUSSIN DM NF 2-15-7.5 MG/5 ML WesTussin DM NF	69367035316	$0.0463 per ML	—	Generic OTC	—	Westminster Pharmaceuticals LLC
CHILD MUCINEX MULTI-SYMPTOM LQ Dextromethorphan Hydrobromide, Guaifenesin, and Phenylephrine Hydrochloride	63824028267	$0.0460 per ML	—	Brand OTC	—	RB Health (US) LLC
GS HEMORRHOIDAL CREAM glycerin, phenylephrine HCl, pramoxine HCl, white petrolatum	00113094424	$0.0453 per GM	-0.33%	Generic OTC	—	L. Perrigo Company
WESTUSSIN DM 1-5-10 MG/5 ML SYR dexchlorpheniramine maleate, dextromethorphan hbr, phenylephrine hcl	69367033416	$0.0410 per ML	—	Generic OTC	—	Westminster Pharmaceuticals LLC
ROBITUSSIN COUGH-COLD CF LIQ dextromethorphan hydrobromide, guaifenesin, and phenylephrine hydrochloride	00031871612	$0.0372 per ML	—	Brand OTC	—	Haleon US Holdings LLC
ADT ROBITUSSIN PEAK CLD M-S LQ dextromethorphan hydrobromide, guaifenesin, and phenylephrine hydrochloride	00031874214	$0.0368 per ML	—	Brand OTC	—	Haleon US Holdings LLC
VICKS DAYQUIL SEVERE COLD-FLU Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, and Phenylephrine Hydrochloride	37000081008	$0.0303 per ML	—	Brand OTC	—	The Procter & Gamble Manufacturing Company
VICKS NYQUIL SEVERE COLD-FLU Acetaminophen, Dextromethorphan Hydrobromide, Doxylamine Succinate, and Phenylephrine Hydrochloride	37000081208	$0.0293 per ML	—	Brand OTC	—	The Procter & Gamble Manufacturing Company
VICKS NYQUIL SEVERE COLD-FLU acetaminophen, dextromethorphan hydrobromide, doxylamine succinate, and phenylephrine hydrochloride	37000081508	$0.0293 per ML	—	Brand OTC	—	The Procter & Gamble Manufacturing Company
ADT ROBITUSSIN PEAK CLD M-S LQ dextromethorphan hydrobromide, guaifenesin, and phenylephrine hydrochloride	00031874220	$0.0284 per ML	—	Brand OTC	—	Haleon US Holdings LLC
TUSNEL DM PEDIATRIC LIQUID Dextromethorphan HBr, Guaifenesin, Phenylephrine HCl	54859060416	$0.0276 per ML	—	Generic OTC	—	Llorens Pharmaceutical International Division
CHILD COLD-ALLERGY LIQUID Brompheniramine maleate, Phenylephrine HCl	70000005701	$0.0248 per ML	-0.16%	Generic OTC	—	Cardinal Health
QC CHILD'S DIBROMM COLD-ALLGY Brompheniramine maleate, Phenylephrine HCl	83324015604	$0.0248 per ML	-0.16%	Generic OTC	—	Chain Drug Marketing Association
TUSSIN CF MAX SEVERE M-S COLD Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, Phenylephrine Hydrochloride	70000062301	$0.0241 per ML	—	Generic OTC	—	Cardinal Health
VICKS NYQUIL SEVERE COLD-FLU Acetaminophen, Dextromethorphan Hydrobromide, Doxylamine Succinate, and Phenylephrine Hydrochloride	37000081212	$0.0235 per ML	—	Brand OTC	—	The Procter & Gamble Manufacturing Company
VICKS NYQUIL SEVERE COLD-FLU acetaminophen, dextromethorphan hydrobromide, doxylamine succinate, and phenylephrine hydrochloride	37000081512	$0.0235 per ML	—	Brand OTC	—	The Procter & Gamble Manufacturing Company
HM CHILD'S DIBROMM COLD-ALLGY Brompheniramine maleate, Phenylephrine HCl	62011044301	$0.0225 per ML	—	Generic OTC	—	Strategic Sourcing Services LLC
SM CHILD COLD-ALLERGY LIQUID Brompheniramine maleate, Phenylephrine HCl	70677010101	$0.0225 per ML	—	Generic OTC	—	Strategic Sourcing Services LLC
THERAFLU EXPRESSMAX COLD NT LQ Acetaminophen, Diphenhydramine HCl, Phenylephrine HCl	00067812908	$0.0221 per ML	—	Brand OTC	—	Haleon US Holdings LLC
THERAFLU EXPRESSMAX COLD-COUGH Acetaminophen, Dextromethorphan HBr, Phenylephrine HCl	00067812708	$0.0214 per ML	—	Brand OTC	High Outlier	Haleon US Holdings LLC
ROBAFEN CF LIQUID Dextromethorphan HBr, Guaifenesin, Phenylephrine	00904653720	$0.0208 per ML	+0.39%	Generic OTC	—	Major Pharmaceuticals
QC ADULT TUSSIN CF LIQUID Dextromethorphan HBr Guaifenesin Phenylephrine HCl	83324015504	$0.0208 per ML	+0.39%	Generic OTC	—	Chain Drug Marketing Association
FT ADULT TUSSIN CF LIQUID Dextromethorphan HBr Guaifenesin Phenylephrine HCl	70677118701	$0.0186 per ML	—	Generic OTC	—	Strategic Sourcing Services LLC
GS SEVERE DAYTIME COLD-FLU LIQ acetaminophen, dextromethorphan hbr, guaifenesin, phenylephrine hcl	00113060334	$0.0183 per ML	—	Generic OTC	—	L. Perrigo Company
DAYTIME SEVERE COLD-FLU LIQUID acetaminophen, dextromethorphan hbr, guaifenesin, phenylephrine hcl	70000019201	$0.0183 per ML	—	Generic OTC	—	Cardinal Health
TUSSIN CF MULTI-SYMPTOM COLD Dextromethorphan HBr, Guaifenesin, Phenylephrine HCI	70000013301	$0.0165 per ML	—	Generic OTC	—	Cardinal Health
SM CHILDREN'S COLD-COUGH LIQ Brompheniramine maleate, Dextromethorphan HBr, Phenylephrine HCl	70677012101	$0.0164 per ML	—	Generic OTC	—	Strategic Sourcing Services LLC
CHILDREN'S COLD-COUGH ELIXIR Brompheniramine maleate, Dextromethorphan HBr, Phenylephrine HCl	36800098726	$0.0159 per ML	—	Generic OTC	—	Topco Associates LLC
GS DAY TIME COLD-FLU LIQUID acetaminophen, dextromethorphan Hbr, Phenylephrine HCl	00113065634	$0.0137 per ML	+0.15%	Generic OTC	—	L. Perrigo Company
GNP DAY TIME COLD-FLU LIQUID acetaminophen, dextromethorphan Hbr, Phenylephrine HCl	24385000534	$0.0137 per ML	+0.15%	Generic OTC	—	AmerisourceBergen
FT DAYTIME COLD-FLU RELIEF LIQ acetaminophen, dextromethorphan Hbr, Phenylephrine HCl	70677103101	$0.0137 per ML	+0.15%	Generic OTC	—	Strategic Sourcing Services LLC
DAYTIME COLD-FLU RELIEF LIQUID acetaminophen, dextromethorphan Hbr, Phenylephrine HCl	70000019101	$0.0131 per ML	—	Generic OTC	—	Cardinal Health
FT NIGHT SEVERE COLD-FLU LIQ acetaminophen, dextromethorphan hydrobromide, doxylamine succinate, phenylephrine hydrochloride	70677103001	$0.0129 per ML	—	Generic OTC	—	Strategic Sourcing Services LLC
FT DAYTIME SEVERE COLD-FLU LIQ acetaminophen, dextromethorphan hydrobromide, guaifenesin, phenylephrine hydrochloride	70677102901	$0.0127 per ML	—	Generic OTC	—	Strategic Sourcing Services LLC
PV FLU RELIEF THERAPY LIQUID ACETAMINOPHEN, DIPHENHYDRAMINE HCL, PHENYLEPHRINE HCL	68016015408	$0.0121 per ML	—	Generic OTC	—	Chain Drug Marketing Association
DAYTIME COLD-FLU RELIEF LIQUID acetaminophen, dextromethorphan Hbr, Phenylephrine HCl	70000019102	$0.0113 per ML	+0.27%	Generic OTC	—	Cardinal Health

Frequently Asked Questions

How many drugs are in the alpha-1 Adrenergic Agonist class?

The alpha-1 Adrenergic Agonist class contains 188 NDCs from 31 manufacturers — 130 generic and 58 brand products.

What is the average price of alpha-1 Adrenergic Agonist drugs?

The average NADAC for the alpha-1 Adrenergic Agonist class is $0.5528 per unit across 188 NDCs.

Is generic cheaper than brand in the alpha-1 Adrenergic Agonist class?

Among products priced per ML, the average generic NADAC in this class is $1.1906, versus $0.0568 for brand — brand is currently about 95% cheaper on average.

Which manufacturers make alpha-1 Adrenergic Agonist drugs?

31 manufacturers make drugs in the alpha-1 Adrenergic Agonist class. Ranked by number of NDCs, the largest are RB Health (US) LLC (34), Cardinal Health (23), Strategic Sourcing Services LLC (18), AmerisourceBergen (17), Haleon US Holdings LLC (16).

How has alpha-1 Adrenergic Agonist pricing changed recently?

Over the past 7 days, 41 NDCs in this class rose and 48 fell, with a class-wide average change of -0.3%.