Product Information

IMIQUIMOD 3.75% CREAM is a generic product labeled by Sun Pharmaceutical Industries Inc., priced at $36.2180 per EA under NDC 51672417406. Its NADAC has been published 123 times since Apr 17, 2024.

FDA first approved this application on Jan 26, 2021. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

IMIQUIMOD 3.75% CREAM

Imiquimod
$36.2180per EA

Strength

37.5 mg/g

NDC

51672417406

Classification

Generic

Dosage Form

CREAM

Route

TOPICAL

Effective Date

8/19/2026

Active Ingredients

IMIQUIMOD

Approval Type

Generic (ANDA)

FDA Application

ANDA205971

FDA Approved

1/26/2021

TE Code

AB

On Market Since

1/26/2021

Pharmacological Classes

Increased Cytokine Activity
Increased Cytokine Production
Interferon Inducers

Price Statistics

The NADAC for IMIQUIMOD 3.75% CREAM has been published 123 times since Apr 17, 2024, and over the history we have for it it has risen 48.5%. The table below summarizes its recorded NADAC range and movement.

Current price$36.2180 per EA
All-time high$36.3836 (Jul 15, 2026)
All-time low$21.6240 (May 21, 2025)
52-week high$36.3836
52-week low$22.0395
Median price$22.0395
Average price$23.7459
Largest weekly change+65.1% (Jun 17, 2026)
Weeks tracked123
Tracking sinceApr 17, 2024

Price History

1W

+0.3%

1M

+0.3%

3M

+64.3%

6M

+64.3%

1Y

+64.3%

3Y

N/A

5Y

N/A

All

+48.5%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Imiquimod market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Frequently asked questions

What is the NADAC price of IMIQUIMOD 3.75% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for IMIQUIMOD 3.75% CREAM, manufactured by Sun Pharmaceutical Industries Inc., is $36.2180 per EA (NDC 51672417406), effective Aug 19, 2026.

How has the price of IMIQUIMOD 3.75% CREAM changed over time?

Over the history we have for it, the NADAC for IMIQUIMOD 3.75% CREAM has risen 48.5%. It has been tracked across 123 weekly CMS publications since Apr 17, 2024.

What are the highest and lowest recorded NADAC prices for IMIQUIMOD 3.75% CREAM?

Since Apr 17, 2024, the NADAC for IMIQUIMOD 3.75% CREAM has ranged from a low of $21.6240 (May 21, 2025) to a high of $36.3836 (Jul 15, 2026), with a median of $22.0395 per EA.

Are there cheaper alternatives to IMIQUIMOD 3.75% CREAM?

No other NADAC-published product currently shares the active ingredient and strength of IMIQUIMOD 3.75% CREAM in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures IMIQUIMOD 3.75% CREAM?

IMIQUIMOD 3.75% CREAM (NDC 51672417406) is labeled by Sun Pharmaceutical Industries Inc., and CMS classifies it as a generic product.