Product Information
ISOSORBIDE-HYDRALAZINE 20-37.5 MG TABLET is a generic product labeled by Wilshire Pharmaceuticals Inc., priced at $0.7138 per EA under NDC 52536000609. Its NADAC has been published 211 times since Sep 21, 2022.
FDA first approved this application on Jun 23, 2005. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
ISOSORBIDE-HYDRALAZINE 20-37.5 MG TABLET
hydralazine hydrochloride and isosorbide dinitrateStrength
37.5; 20 mg/1; mg/1
Manufacturer
Wilshire Pharmaceuticals Inc.NDC
52536000609
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
HYDRALAZINE HYDROCHLORIDE; ISOSORBIDE DINITRATEApproval Type
Authorized Generic (NDA)
FDA Application
NDA020727FDA Approved
6/23/2005
TE Code
AB
On Market Since
4/15/2022
Pharmacological Classes
Price Statistics
The NADAC for ISOSORBIDE-HYDRALAZINE 20-37.5 MG TABLET has been published 211 times since Sep 21, 2022, and over the history we have for it it has declined 48.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.7138 per EA |
|---|---|
| All-time high | $2.2084 (Aug 16, 2023) |
| All-time low | $0.6998 (Nov 19, 2025) |
| 52-week high | $0.7961 |
| 52-week low | $0.6998 |
| Median price | $0.9769 |
| Average price | $1.1637 |
| Largest weekly change | -22.9% (Aug 23, 2023) |
| Weeks tracked | 211 |
| Tracking since | Sep 21, 2022 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the hydralazine hydrochloride and isosorbide dinitrate market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Wilshire Pharmaceuticals Inc. manufacturer profile
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Drug market
hydralazine hydrochloride and isosorbide dinitrate market comparison
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Therapeutic class
Arteriolar Vasodilator class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
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Frequently asked questions
What is the NADAC price of ISOSORBIDE-HYDRALAZINE 20-37.5 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for ISOSORBIDE-HYDRALAZINE 20-37.5 MG TABLET, manufactured by Wilshire Pharmaceuticals Inc., is $0.7138 per EA (NDC 52536000609), effective Sep 30, 2026.
How has the price of ISOSORBIDE-HYDRALAZINE 20-37.5 MG TABLET changed over time?
Over the history we have for it, the NADAC for ISOSORBIDE-HYDRALAZINE 20-37.5 MG TABLET has declined 48.1%. It has been tracked across 211 weekly CMS publications since Sep 21, 2022.
What are the highest and lowest recorded NADAC prices for ISOSORBIDE-HYDRALAZINE 20-37.5 MG TABLET?
Since Sep 21, 2022, the NADAC for ISOSORBIDE-HYDRALAZINE 20-37.5 MG TABLET has ranged from a low of $0.6998 (Nov 19, 2025) to a high of $2.2084 (Aug 16, 2023), with a median of $0.9769 per EA.
Are there cheaper alternatives to ISOSORBIDE-HYDRALAZINE 20-37.5 MG TABLET?
No other NADAC-published product currently shares the active ingredient and strength of ISOSORBIDE-HYDRALAZINE 20-37.5 MG TABLET in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures ISOSORBIDE-HYDRALAZINE 20-37.5 MG TABLET?
ISOSORBIDE-HYDRALAZINE 20-37.5 MG TABLET (NDC 52536000609) is labeled by Wilshire Pharmaceuticals Inc., and CMS classifies it as a generic product.