Product Information
MATZIM LA 420 MG TABLET is a generic product labeled by Actavis Pharma, Inc., priced at $2.5418 per EA under NDC 52544069530. Its NADAC has been published 505 times since Nov 28, 2013.
FDA first approved this application on Mar 15, 2010. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
420 mg/1
Manufacturer
Actavis Pharma, Inc.NDC
52544069530
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
DILTIAZEM HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA077686FDA Approved
3/15/2010
TE Code
AB
On Market Since
3/28/2011
Pharmacological Classes
Price Statistics
The NADAC for MATZIM LA 420 MG TABLET has been published 505 times since Nov 28, 2013, and over the history we have for it it has declined 35.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.5418 per EA |
|---|---|
| All-time high | $4.0182 (Jan 13, 2016) |
| All-time low | $2.0522 (Aug 21, 2024) |
| 52-week high | $3.2373 |
| 52-week low | $2.3130 |
| Median price | $3.6877 |
| Average price | $3.4395 |
| Largest weekly change | -15.5% (May 22, 2024) |
| Weeks tracked | 505 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 5% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of MATZIM LA 420 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for MATZIM LA 420 MG TABLET, manufactured by Actavis Pharma, Inc., is $2.5418 per EA (NDC 52544069530), effective Aug 19, 2026.
How has the price of MATZIM LA 420 MG TABLET changed over time?
Over the history we have for it, the NADAC for MATZIM LA 420 MG TABLET has declined 35.4%. It has been tracked across 505 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for MATZIM LA 420 MG TABLET?
Since Nov 28, 2013, the NADAC for MATZIM LA 420 MG TABLET has ranged from a low of $2.0522 (Aug 21, 2024) to a high of $4.0182 (Jan 13, 2016), with a median of $3.6877 per EA.
Are there cheaper alternatives to MATZIM LA 420 MG TABLET?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DILTIAZEM 24H ER(LA) 420 MG TB, is $2.4083 per EA — about 5% below MATZIM LA 420 MG TABLET.
Who manufactures MATZIM LA 420 MG TABLET?
MATZIM LA 420 MG TABLET (NDC 52544069530) is labeled by Actavis Pharma, Inc., and CMS classifies it as a generic product.