Product Information

DILTIAZEM 24H ER(LA) 420 MG TB is a generic product labeled by Slate Run Pharmaceuticals LLC, priced at $2.5418 per EA under NDC 70436020004. Its NADAC has been published 123 times since Apr 17, 2024.

FDA first approved this application on Mar 7, 2023. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

DILTIAZEM 24H ER(LA) 420 MG TB

Diltiazem Hydrochloride
$2.5418per EA

Strength

420 mg/1

NDC

70436020004

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

DILTIAZEM HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA216439

FDA Approved

3/7/2023

TE Code

AB

On Market Since

3/20/2023

Pharmacological Classes

Calcium Channel Antagonists
Calcium Channel Blocker
Cytochrome P450 3A4 Inhibitors

Price Statistics

The NADAC for DILTIAZEM 24H ER(LA) 420 MG TB has been published 123 times since Apr 17, 2024, and over the history we have for it it has declined 12.5%. The table below summarizes its recorded NADAC range and movement.

Current price$2.5418 per EA
All-time high$3.2373 (Oct 15, 2025)
All-time low$2.0522 (Aug 21, 2024)
52-week high$3.2373
52-week low$2.3130
Median price$2.5418
Average price$2.5923
Largest weekly change-15.5% (May 22, 2024)
Weeks tracked123
Tracking sinceApr 17, 2024

Price History

1W

+1.5%

1M

+1.5%

3M

+5.5%

6M

+7.6%

1Y

-17.8%

3Y

N/A

5Y

N/A

All

-12.5%

Generic Alternatives

The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 5% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of DILTIAZEM 24H ER(LA) 420 MG TB?

The current National Average Drug Acquisition Cost (NADAC) for DILTIAZEM 24H ER(LA) 420 MG TB, manufactured by Slate Run Pharmaceuticals LLC, is $2.5418 per EA (NDC 70436020004), effective Aug 19, 2026.

How has the price of DILTIAZEM 24H ER(LA) 420 MG TB changed over time?

Over the history we have for it, the NADAC for DILTIAZEM 24H ER(LA) 420 MG TB has declined 12.5%. It has been tracked across 123 weekly CMS publications since Apr 17, 2024.

What are the highest and lowest recorded NADAC prices for DILTIAZEM 24H ER(LA) 420 MG TB?

Since Apr 17, 2024, the NADAC for DILTIAZEM 24H ER(LA) 420 MG TB has ranged from a low of $2.0522 (Aug 21, 2024) to a high of $3.2373 (Oct 15, 2025), with a median of $2.5418 per EA.

Are there cheaper alternatives to DILTIAZEM 24H ER(LA) 420 MG TB?

Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DILTIAZEM 24H ER(LA) 420 MG TB, is $2.4083 per EA — about 5% below DILTIAZEM 24H ER(LA) 420 MG TB.

Who manufactures DILTIAZEM 24H ER(LA) 420 MG TB?

DILTIAZEM 24H ER(LA) 420 MG TB (NDC 70436020004) is labeled by Slate Run Pharmaceuticals LLC, and CMS classifies it as a generic product.