Product Information
HYDROCODONE-IBUPROFEN 5-200 MG is a generic product labeled by Amneal Pharmaceuticals of New York LLC, priced at $2.5716 per EA under NDC 53746014601. Its NADAC has been published 324 times since Nov 28, 2013.
FDA first approved this application on Mar 18, 2004. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
5; 200 mg/1; mg/1
Manufacturer
Amneal Pharmaceuticals of New York LLCNDC
53746014601
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
3/18/2026
Active Ingredients
HYDROCODONE BITARTRATE; IBUPROFENApproval Type
Generic (ANDA)
FDA Application
ANDA076642FDA Approved
3/18/2004
TE Code
AB
On Market Since
2/18/2010
Pharmacological Classes
Price Statistics
The NADAC for HYDROCODONE-IBUPROFEN 5-200 MG has been published 324 times since Nov 28, 2013, and over the history we have for it it has risen 12.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.5716 per EA |
|---|---|
| All-time high | $2.7512 (Sep 10, 2025) |
| All-time low | $1.7672 (Dec 18, 2013) |
| 52-week high | $2.6722 |
| 52-week low | $2.5603 |
| Median price | $2.2373 |
| Average price | $2.2294 |
| Largest weekly change | +28.3% (Aug 20, 2025) |
| Weeks tracked | 324 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Hydrocodone Bitartrate and Ibuprofen market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Amneal Pharmaceuticals of New York LLC manufacturer profile
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Drug market
Hydrocodone Bitartrate and Ibuprofen market comparison
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Therapeutic class
Nonsteroidal Anti-inflammatory Drug class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of HYDROCODONE-IBUPROFEN 5-200 MG?
The current National Average Drug Acquisition Cost (NADAC) for HYDROCODONE-IBUPROFEN 5-200 MG, manufactured by Amneal Pharmaceuticals of New York LLC, is $2.5716 per EA (NDC 53746014601), effective Sep 30, 2026.
How has the price of HYDROCODONE-IBUPROFEN 5-200 MG changed over time?
Over the history we have for it, the NADAC for HYDROCODONE-IBUPROFEN 5-200 MG has risen 12.5%. It has been tracked across 324 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for HYDROCODONE-IBUPROFEN 5-200 MG?
Since Nov 28, 2013, the NADAC for HYDROCODONE-IBUPROFEN 5-200 MG has ranged from a low of $1.7672 (Dec 18, 2013) to a high of $2.7512 (Sep 10, 2025), with a median of $2.2373 per EA.
Are there cheaper alternatives to HYDROCODONE-IBUPROFEN 5-200 MG?
No other NADAC-published product currently shares the active ingredient and strength of HYDROCODONE-IBUPROFEN 5-200 MG in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures HYDROCODONE-IBUPROFEN 5-200 MG?
HYDROCODONE-IBUPROFEN 5-200 MG (NDC 53746014601) is labeled by Amneal Pharmaceuticals of New York LLC, and CMS classifies it as a generic product.