Product Information
HYDROCODONE-IBUPROFEN 5-200 MG is a generic product labeled by Amneal Pharmaceuticals of New York LLC, priced at $2.5716 per EA under NDC 53746014601. Its NADAC has been published 318 times since Nov 28, 2013.
FDA first approved this application on Mar 18, 2004. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
5; 200 mg/1; mg/1
Manufacturer
Amneal Pharmaceuticals of New York LLCNDC
53746014601
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
3/18/2026
Active Ingredients
HYDROCODONE BITARTRATE; IBUPROFENApproval Type
Generic (ANDA)
FDA Application
ANDA076642FDA Approved
3/18/2004
TE Code
AB
On Market Since
2/18/2010
Pharmacological Classes
Price Statistics
The NADAC for HYDROCODONE-IBUPROFEN 5-200 MG has been published 318 times since Nov 28, 2013, and over the history we have for it it has risen 12.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.5716 per EA |
|---|---|
| All-time high | $2.7512 (Sep 10, 2025) |
| All-time low | $1.7672 (Dec 18, 2013) |
| 52-week high | $2.7512 |
| 52-week low | $2.5603 |
| Median price | $2.2206 |
| Average price | $2.2230 |
| Largest weekly change | +28.3% (Aug 20, 2025) |
| Weeks tracked | 318 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Hydrocodone Bitartrate and Ibuprofen market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of HYDROCODONE-IBUPROFEN 5-200 MG?
The current National Average Drug Acquisition Cost (NADAC) for HYDROCODONE-IBUPROFEN 5-200 MG, manufactured by Amneal Pharmaceuticals of New York LLC, is $2.5716 per EA (NDC 53746014601), effective Aug 19, 2026.
How has the price of HYDROCODONE-IBUPROFEN 5-200 MG changed over time?
Over the history we have for it, the NADAC for HYDROCODONE-IBUPROFEN 5-200 MG has risen 12.5%. It has been tracked across 318 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for HYDROCODONE-IBUPROFEN 5-200 MG?
Since Nov 28, 2013, the NADAC for HYDROCODONE-IBUPROFEN 5-200 MG has ranged from a low of $1.7672 (Dec 18, 2013) to a high of $2.7512 (Sep 10, 2025), with a median of $2.2206 per EA.
Are there cheaper alternatives to HYDROCODONE-IBUPROFEN 5-200 MG?
No other NADAC-published product currently shares the active ingredient and strength of HYDROCODONE-IBUPROFEN 5-200 MG in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures HYDROCODONE-IBUPROFEN 5-200 MG?
HYDROCODONE-IBUPROFEN 5-200 MG (NDC 53746014601) is labeled by Amneal Pharmaceuticals of New York LLC, and CMS classifies it as a generic product.