Product Information
DEMECLOCYCLINE 300 MG TABLET is a generic product labeled by Amneal Pharmaceuticals of New York LLC, priced at $3.0577 per EA under NDC 53746055548. Its NADAC has been published 123 times since Apr 17, 2024.
FDA first approved this application on Feb 27, 2008. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
300 mg/1
Manufacturer
Amneal Pharmaceuticals of New York LLCNDC
53746055548
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
DEMECLOCYCLINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA065425FDA Approved
2/27/2008
TE Code
AB
On Market Since
5/25/2022
Pharmacological Classes
Price Statistics
The NADAC for DEMECLOCYCLINE 300 MG TABLET has been published 123 times since Apr 17, 2024, and over the history we have for it it has declined 51.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $3.0577 per EA |
|---|---|
| All-time high | $6.2676 (May 15, 2024) |
| All-time low | $3.0577 (Aug 19, 2026) |
| 52-week high | $5.9961 |
| 52-week low | $3.0577 |
| Median price | $5.1875 |
| Average price | $5.1051 |
| Largest weekly change | -42.1% (Apr 22, 2026) |
| Weeks tracked | 123 |
| Tracking since | Apr 17, 2024 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DEMECLOCYCLINE 300 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for DEMECLOCYCLINE 300 MG TABLET, manufactured by Amneal Pharmaceuticals of New York LLC, is $3.0577 per EA (NDC 53746055548), effective Aug 19, 2026.
How has the price of DEMECLOCYCLINE 300 MG TABLET changed over time?
Over the history we have for it, the NADAC for DEMECLOCYCLINE 300 MG TABLET has declined 51.2%. It has been tracked across 123 weekly CMS publications since Apr 17, 2024.
What are the highest and lowest recorded NADAC prices for DEMECLOCYCLINE 300 MG TABLET?
Since Apr 17, 2024, the NADAC for DEMECLOCYCLINE 300 MG TABLET has ranged from a low of $3.0577 (Aug 19, 2026) to a high of $6.2676 (May 15, 2024), with a median of $5.1875 per EA.
Are there cheaper alternatives to DEMECLOCYCLINE 300 MG TABLET?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as DEMECLOCYCLINE 300 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures DEMECLOCYCLINE 300 MG TABLET?
DEMECLOCYCLINE 300 MG TABLET (NDC 53746055548) is labeled by Amneal Pharmaceuticals of New York LLC, and CMS classifies it as a generic product.