Product Information

ZOLOFT 50 MG TABLET is a brand product labeled by Viatris Specialty LLC, priced at $14.9220 per EA under NDC 58151057588. Its NADAC has been published 51 times since Sep 3, 2025.

FDA first approved this application on Dec 30, 1991. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The High Outlier badge above means this manufacturer's average price in the sertraline hydrochloride market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

ZOLOFT 50 MG TABLET

sertraline hydrochloride
$14.9220per EA
High Outlier

Strength

50 mg/1

NDC

58151057588

Classification

Brand

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

SERTRALINE HYDROCHLORIDE

Approval Type

New Drug (NDA)

FDA Application

NDA019839

FDA Approved

12/30/1991

TE Code

AB

On Market Since

7/8/2025

Pharmacological Classes

Cytochrome P450 2D6 Inhibitors
Serotonin Reuptake Inhibitor
Serotonin Uptake Inhibitors

Price Statistics

The NADAC for ZOLOFT 50 MG TABLET has been published 51 times since Sep 3, 2025, and over the history we have for it it has risen 5.1%. The table below summarizes its recorded NADAC range and movement.

Current price$14.9220 per EA
All-time high$14.9258 (May 13, 2026)
All-time low$14.1980 (Sep 3, 2025)
52-week high$14.9258
52-week low$14.1980
Median price$14.8841
Average price$14.6608
Largest weekly change+5.0% (Jan 7, 2026)
Weeks tracked51
Tracking sinceSep 3, 2025

Price History

1W

-0.0%

1M

-0.0%

3M

+0.5%

6M

-0.0%

1Y

N/A

3Y

N/A

5Y

N/A

All

+5.1%

Generic Alternatives

The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 99% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of ZOLOFT 50 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for ZOLOFT 50 MG TABLET, manufactured by Viatris Specialty LLC, is $14.9220 per EA (NDC 58151057588), effective Aug 19, 2026.

How has the price of ZOLOFT 50 MG TABLET changed over time?

Over the history we have for it, the NADAC for ZOLOFT 50 MG TABLET has risen 5.1%. It has been tracked across 51 weekly CMS publications since Sep 3, 2025.

What are the highest and lowest recorded NADAC prices for ZOLOFT 50 MG TABLET?

Since Sep 3, 2025, the NADAC for ZOLOFT 50 MG TABLET has ranged from a low of $14.1980 (Sep 3, 2025) to a high of $14.9258 (May 13, 2026), with a median of $14.8841 per EA.

Are there cheaper alternatives to ZOLOFT 50 MG TABLET?

Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, SERTRALINE HCL 50 MG TABLET, is $0.0345 per EA — about 99% below ZOLOFT 50 MG TABLET.

Who manufactures ZOLOFT 50 MG TABLET?

ZOLOFT 50 MG TABLET (NDC 58151057588) is labeled by Viatris Specialty LLC, and CMS classifies it as a brand product.