Product Information

ENBREL 50 MG/ML MINI CARTRIDGE is a brand product labeled by Immunex Corporation, priced at $2080.9950 per ML under NDC 58406004404. Its NADAC has been published 336 times since Mar 18, 2020.

ENBREL 50 MG/ML MINI CARTRIDGE

etanercept
$2080.9950per ML

Strength

50 mg/mL

NDC

58406004404

Classification

Brand

Dosage Form

SOLUTION

Route

SUBCUTANEOUS

Effective Date

8/19/2026

Active Ingredients

ETANERCEPT

Approval Type

Biologic (BLA)

FDA Application

BLA103795

On Market Since

6/7/2019

Pharmacological Classes

Tumor Necrosis Factor Blocker
Tumor Necrosis Factor Receptor Blocking Activity

Price Statistics

The NADAC for ENBREL 50 MG/ML MINI CARTRIDGE has been published 336 times since Mar 18, 2020, and over the history we have for it it has risen 53.4%. The table below summarizes its recorded NADAC range and movement.

Current price$2080.9950 per ML
All-time high$2083.3742 (Jun 10, 2026)
All-time low$1354.5046 (Jul 22, 2020)
52-week high$2083.3742
52-week low$1981.8062
Median price$1715.1073
Average price$1697.9133
Largest weekly change+7.4% (Feb 3, 2021)
Weeks tracked336
Tracking sinceMar 18, 2020

Price History

1W

+0.0%

1M

+0.0%

3M

-0.1%

6M

-0.0%

1Y

+5.0%

3Y

+21.3%

5Y

+43.0%

All

+53.4%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 0% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 0%

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of ENBREL 50 MG/ML MINI CARTRIDGE?

The current National Average Drug Acquisition Cost (NADAC) for ENBREL 50 MG/ML MINI CARTRIDGE, manufactured by Immunex Corporation, is $2080.9950 per ML (NDC 58406004404), effective Aug 19, 2026.

How has the price of ENBREL 50 MG/ML MINI CARTRIDGE changed over time?

Over the history we have for it, the NADAC for ENBREL 50 MG/ML MINI CARTRIDGE has risen 53.4%. It has been tracked across 336 weekly CMS publications since Mar 18, 2020.

What are the highest and lowest recorded NADAC prices for ENBREL 50 MG/ML MINI CARTRIDGE?

Since Mar 18, 2020, the NADAC for ENBREL 50 MG/ML MINI CARTRIDGE has ranged from a low of $1354.5046 (Jul 22, 2020) to a high of $2083.3742 (Jun 10, 2026), with a median of $1715.1073 per ML.

Are there cheaper alternatives to ENBREL 50 MG/ML MINI CARTRIDGE?

Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ENBREL 50 MG/ML SYRINGE, is $2080.6750 per ML — about 0% below ENBREL 50 MG/ML MINI CARTRIDGE.

Who manufactures ENBREL 50 MG/ML MINI CARTRIDGE?

ENBREL 50 MG/ML MINI CARTRIDGE (NDC 58406004404) is labeled by Immunex Corporation, and CMS classifies it as a brand product.