Product Information
ENBREL 50 MG/ML MINI CARTRIDGE is a brand product labeled by Immunex Corporation, priced at $2080.9950 per ML under NDC 58406004404. Its NADAC has been published 342 times since Mar 18, 2020.
Strength
50 mg/mL
Manufacturer
Immunex CorporationNDC
58406004404
Classification
Brand
Dosage Form
SOLUTION
Route
SUBCUTANEOUS
Effective Date
9/23/2026
Active Ingredients
ETANERCEPTApproval Type
Biologic (BLA)
FDA Application
BLA103795On Market Since
6/7/2019
Pharmacological Classes
Price Statistics
The NADAC for ENBREL 50 MG/ML MINI CARTRIDGE has been published 342 times since Mar 18, 2020, and over the history we have for it it has risen 53.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2080.9950 per ML |
|---|---|
| All-time high | $2083.3742 (Jun 10, 2026) |
| All-time low | $1354.5046 (Jul 22, 2020) |
| 52-week high | $2083.3742 |
| 52-week low | $1981.8062 |
| Median price | $1715.1073 |
| Average price | $1704.6340 |
| Largest weekly change | +7.4% (Feb 3, 2021) |
| Weeks tracked | 342 |
| Tracking since | Mar 18, 2020 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 0% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Immunex Corporation manufacturer profile
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Drug market
etanercept market comparison
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Therapeutic class
Tumor Necrosis Factor Blocker class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of ENBREL 50 MG/ML MINI CARTRIDGE?
The current National Average Drug Acquisition Cost (NADAC) for ENBREL 50 MG/ML MINI CARTRIDGE, manufactured by Immunex Corporation, is $2080.9950 per ML (NDC 58406004404), effective Sep 30, 2026.
How has the price of ENBREL 50 MG/ML MINI CARTRIDGE changed over time?
Over the history we have for it, the NADAC for ENBREL 50 MG/ML MINI CARTRIDGE has risen 53.4%. It has been tracked across 342 weekly CMS publications since Mar 18, 2020.
What are the highest and lowest recorded NADAC prices for ENBREL 50 MG/ML MINI CARTRIDGE?
Since Mar 18, 2020, the NADAC for ENBREL 50 MG/ML MINI CARTRIDGE has ranged from a low of $1354.5046 (Jul 22, 2020) to a high of $2083.3742 (Jun 10, 2026), with a median of $1715.1073 per ML.
Are there cheaper alternatives to ENBREL 50 MG/ML MINI CARTRIDGE?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ENBREL 50 MG/ML SYRINGE, is $2080.5922 per ML — about 0% below ENBREL 50 MG/ML MINI CARTRIDGE.
Who manufactures ENBREL 50 MG/ML MINI CARTRIDGE?
ENBREL 50 MG/ML MINI CARTRIDGE (NDC 58406004404) is labeled by Immunex Corporation, and CMS classifies it as a brand product.