Product Information
ENBREL 50 MG/ML SYRINGE is a brand product labeled by Immunex Corporation, priced at $2080.5922 per ML under NDC 58406002104. Its NADAC has been published 355 times since Dec 18, 2019.
Strength
50 mg/mL
Manufacturer
Immunex CorporationNDC
58406002104
Classification
Brand
Dosage Form
SOLUTION
Route
SUBCUTANEOUS
Effective Date
9/23/2026
Active Ingredients
ETANERCEPTApproval Type
Biologic (BLA)
FDA Application
BLA103795On Market Since
6/7/2019
Pharmacological Classes
Price Statistics
The NADAC for ENBREL 50 MG/ML SYRINGE has been published 355 times since Dec 18, 2019, and over the history we have for it it has risen 65.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2080.5922 per ML |
|---|---|
| All-time high | $2080.7524 (Jul 15, 2026) |
| All-time low | $1260.6598 (Dec 18, 2019) |
| 52-week high | $2080.7524 |
| 52-week low | $1980.9669 |
| Median price | $1715.0696 |
| Average price | $1689.5511 |
| Largest weekly change | +7.4% (Jan 11, 2023) |
| Weeks tracked | 355 |
| Tracking since | Dec 18, 2019 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Immunex Corporation manufacturer profile
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Drug market
etanercept market comparison
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Therapeutic class
Tumor Necrosis Factor Blocker class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of ENBREL 50 MG/ML SYRINGE?
The current National Average Drug Acquisition Cost (NADAC) for ENBREL 50 MG/ML SYRINGE, manufactured by Immunex Corporation, is $2080.5922 per ML (NDC 58406002104), effective Sep 30, 2026.
How has the price of ENBREL 50 MG/ML SYRINGE changed over time?
Over the history we have for it, the NADAC for ENBREL 50 MG/ML SYRINGE has risen 65.0%. It has been tracked across 355 weekly CMS publications since Dec 18, 2019.
What are the highest and lowest recorded NADAC prices for ENBREL 50 MG/ML SYRINGE?
Since Dec 18, 2019, the NADAC for ENBREL 50 MG/ML SYRINGE has ranged from a low of $1260.6598 (Dec 18, 2019) to a high of $2080.7524 (Jul 15, 2026), with a median of $1715.0696 per ML.
Are there cheaper alternatives to ENBREL 50 MG/ML SYRINGE?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as ENBREL 50 MG/ML SYRINGE in a comparable dosage form, but none are currently priced below it.
Who manufactures ENBREL 50 MG/ML SYRINGE?
ENBREL 50 MG/ML SYRINGE (NDC 58406002104) is labeled by Immunex Corporation, and CMS classifies it as a brand product.