Product Information

ENBREL 50 MG/ML SYRINGE is a brand product labeled by Immunex Corporation, priced at $2080.7524 per ML under NDC 58406002104. Its NADAC has been published 341 times since Dec 18, 2019.

ENBREL 50 MG/ML SYRINGE

etanercept
$2080.7524per ML

Strength

50 mg/mL

NDC

58406002104

Classification

Brand

Dosage Form

SOLUTION

Route

SUBCUTANEOUS

Last Updated

6/17/2026

Active Ingredients

ETANERCEPT

Approval Type

Biologic (BLA)

FDA Application

BLA103795

On Market Since

6/7/2019

Pharmacological Classes

Tumor Necrosis Factor Blocker
Tumor Necrosis Factor Receptor Blocking Activity

Price Statistics

The NADAC for ENBREL 50 MG/ML SYRINGE has been published 341 times since Dec 18, 2019, and over the history we have for it it has risen 65.1%. The table below summarizes its recorded NADAC range and movement.

Current price$2080.7524 per ML
All-time high$2080.7524 (Jun 24, 2026)
All-time low$1260.6598 (Dec 18, 2019)
52-week high$2080.7524
52-week low$1980.8130
Median price$1715.0696
Average price$1673.4950
Largest weekly change+7.4% (Jan 11, 2023)
Weeks tracked341
Tracking sinceDec 18, 2019

Price History

1W

0.0%

1M

+0.0%

3M

+0.0%

6M

+5.0%

1Y

+5.0%

3Y

+21.3%

5Y

+43.2%

All

+65.1%

Generic Alternatives

The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 0% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 0%

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of ENBREL 50 MG/ML SYRINGE?

The current National Average Drug Acquisition Cost (NADAC) for ENBREL 50 MG/ML SYRINGE, manufactured by Immunex Corporation, is $2080.7524 per ML (NDC 58406002104), effective Jun 24, 2026.

How has the price of ENBREL 50 MG/ML SYRINGE changed over time?

Over the history we have for it, the NADAC for ENBREL 50 MG/ML SYRINGE has risen 65.1%. It has been tracked across 341 weekly CMS publications since Dec 18, 2019.

What are the highest and lowest recorded NADAC prices for ENBREL 50 MG/ML SYRINGE?

Since Dec 18, 2019, the NADAC for ENBREL 50 MG/ML SYRINGE has ranged from a low of $1260.6598 (Dec 18, 2019) to a high of $2080.7524 (Jun 24, 2026), with a median of $1715.0696 per ML.

Are there cheaper alternatives to ENBREL 50 MG/ML SYRINGE?

Yes. 1 NADAC-published product shares the same active ingredient, strength, and dosage form. The lowest-priced option, ENBREL 50 MG/ML MINI CARTRIDGE, is $2080.5354 per ML — about 0% below ENBREL 50 MG/ML SYRINGE.

Who manufactures ENBREL 50 MG/ML SYRINGE?

ENBREL 50 MG/ML SYRINGE (NDC 58406002104) is labeled by Immunex Corporation, and CMS classifies it as a brand product.