Product Information
GUAIFENESIN 100 MG/5 ML LIQUID is a generic product labeled by Method Pharmaceuticals LLC, priced at $0.0133 per ML under NDC 58657050916. Its NADAC has been published 499 times since Jul 13, 2016.
Strength
100 mg/5mL
Manufacturer
Method Pharmaceuticals LLCNDC
58657050916
Classification
Generic
Dosage Form
LIQUID
Route
ORAL
Effective Date
1/21/2026
Active Ingredients
GUAIFENESINApproval Type
OTC MONOGRAPH DRUG
FDA Application
M012On Market Since
2/9/2016
Pharmacological Classes
Price Statistics
The NADAC for GUAIFENESIN 100 MG/5 ML LIQUID has been published 499 times since Jul 13, 2016, and over the history we have for it it has risen 139.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0133 per ML |
|---|---|
| All-time high | $0.0154 (Feb 10, 2021) |
| All-time low | $0.0050 (Nov 23, 2016) |
| 52-week high | $0.0134 |
| 52-week low | $0.0128 |
| Median price | $0.0095 |
| Average price | $0.0093 |
| Largest weekly change | +40.8% (Jun 23, 2021) |
| Weeks tracked | 499 |
| Tracking since | Jul 13, 2016 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
+4.2%
3Y
+0.6%
5Y
+32.3%
All
+139.1%
Last surveyed Jan 28, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 17% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Method Pharmaceuticals LLC manufacturer profile
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Drug market
Guaifenesin market comparison
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Therapeutic class
Expectorant class view
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Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of GUAIFENESIN 100 MG/5 ML LIQUID?
The current National Average Drug Acquisition Cost (NADAC) for GUAIFENESIN 100 MG/5 ML LIQUID, manufactured by Method Pharmaceuticals LLC, is $0.0133 per ML (NDC 58657050916), effective Jan 28, 2026.
How has the price of GUAIFENESIN 100 MG/5 ML LIQUID changed over time?
Over the history we have for it, the NADAC for GUAIFENESIN 100 MG/5 ML LIQUID has risen 139.1%. It has been tracked across 499 weekly CMS publications since Jul 13, 2016.
What are the highest and lowest recorded NADAC prices for GUAIFENESIN 100 MG/5 ML LIQUID?
Since Jul 13, 2016, the NADAC for GUAIFENESIN 100 MG/5 ML LIQUID has ranged from a low of $0.0050 (Nov 23, 2016) to a high of $0.0154 (Feb 10, 2021), with a median of $0.0095 per ML.
Are there cheaper alternatives to GUAIFENESIN 100 MG/5 ML LIQUID?
Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, GUAIFENESIN 100 MG/5 ML SOLN, is $0.0110 per ML — about 17% below GUAIFENESIN 100 MG/5 ML LIQUID.
Who manufactures GUAIFENESIN 100 MG/5 ML LIQUID?
GUAIFENESIN 100 MG/5 ML LIQUID (NDC 58657050916) is labeled by Method Pharmaceuticals LLC, and CMS classifies it as a generic product.