Product Information

GUAIFENESIN 100 MG/5 ML LIQUID is a generic product labeled by Method Pharmaceuticals LLC, priced at $0.0133 per ML under NDC 58657050916. Its NADAC has been published 499 times since Jul 13, 2016.

GUAIFENESIN 100 MG/5 ML LIQUID

Guaifenesin
$0.0133per ML
OTC

Strength

100 mg/5mL

NDC

58657050916

Classification

Generic

Dosage Form

LIQUID

Route

ORAL

Effective Date

1/21/2026

Active Ingredients

GUAIFENESIN

Approval Type

OTC MONOGRAPH DRUG

FDA Application

M012

On Market Since

2/9/2016

Pharmacological Classes

Decreased Respiratory Secretion Viscosity
Expectorant
Increased Respiratory Secretions

Price Statistics

The NADAC for GUAIFENESIN 100 MG/5 ML LIQUID has been published 499 times since Jul 13, 2016, and over the history we have for it it has risen 139.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0133 per ML
All-time high$0.0154 (Feb 10, 2021)
All-time low$0.0050 (Nov 23, 2016)
52-week high$0.0134
52-week low$0.0128
Median price$0.0095
Average price$0.0093
Largest weekly change+40.8% (Jun 23, 2021)
Weeks tracked499
Tracking sinceJul 13, 2016

Price History

1W

N/A

1M

N/A

3M

N/A

6M

N/A

1Y

+0.1%

3Y

+12.3%

5Y

-2.0%

All

+139.1%

Last surveyed Jan 28, 2026 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 16% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of GUAIFENESIN 100 MG/5 ML LIQUID?

The current National Average Drug Acquisition Cost (NADAC) for GUAIFENESIN 100 MG/5 ML LIQUID, manufactured by Method Pharmaceuticals LLC, is $0.0133 per ML (NDC 58657050916), effective Jan 28, 2026.

How has the price of GUAIFENESIN 100 MG/5 ML LIQUID changed over time?

Over the history we have for it, the NADAC for GUAIFENESIN 100 MG/5 ML LIQUID has risen 139.1%. It has been tracked across 499 weekly CMS publications since Jul 13, 2016.

What are the highest and lowest recorded NADAC prices for GUAIFENESIN 100 MG/5 ML LIQUID?

Since Jul 13, 2016, the NADAC for GUAIFENESIN 100 MG/5 ML LIQUID has ranged from a low of $0.0050 (Nov 23, 2016) to a high of $0.0154 (Feb 10, 2021), with a median of $0.0095 per ML.

Are there cheaper alternatives to GUAIFENESIN 100 MG/5 ML LIQUID?

Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, GUAIFENESIN 100 MG/5 ML SOLN, is $0.0112 per ML — about 16% below GUAIFENESIN 100 MG/5 ML LIQUID.

Who manufactures GUAIFENESIN 100 MG/5 ML LIQUID?

GUAIFENESIN 100 MG/5 ML LIQUID (NDC 58657050916) is labeled by Method Pharmaceuticals LLC, and CMS classifies it as a generic product.