Product Information

REXULTI 4 MG TABLET is a brand product labeled by Otsuka America Pharmaceutical Inc., priced at $49.4674 per EA under NDC 59148004013. Its NADAC has been published 546 times since Apr 20, 2016.

FDA first approved this application on Jul 10, 2015. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

REXULTI 4 MG TABLET

brexpiprazole
$49.4674per EA

Strength

4 mg/1

NDC

59148004013

Classification

Brand

Dosage Form

TABLET

Route

ORAL

Effective Date

9/23/2026

Active Ingredients

BREXPIPRAZOLE

Approval Type

New Drug (NDA)

FDA Application

NDA205422

FDA Approved

7/10/2015

TE Code

AB

On Market Since

7/10/2015

Pharmacological Classes

Price Statistics

The NADAC for REXULTI 4 MG TABLET has been published 546 times since Apr 20, 2016, and over the history we have for it it has risen 74.3%. The table below summarizes its recorded NADAC range and movement.

Current price$49.4674 per EA
All-time high$49.6310 (May 13, 2026)
All-time low$28.3809 (Apr 20, 2016)
52-week high$49.6310
52-week low$48.2848
Median price$39.7070
Average price$40.2403
Largest weekly change+9.9% (Apr 11, 2018)
Weeks tracked546
Tracking sinceApr 20, 2016

Price History

1W

0.0%

1M

-0.1%

3M

-0.3%

6M

-0.3%

1Y

+2.4%

3Y

+9.3%

5Y

+24.6%

All

+74.3%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the brexpiprazole market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Continue researching this drug

Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.

Frequently asked questions

What is the NADAC price of REXULTI 4 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for REXULTI 4 MG TABLET, manufactured by Otsuka America Pharmaceutical Inc., is $49.4674 per EA (NDC 59148004013), effective Sep 30, 2026.

How has the price of REXULTI 4 MG TABLET changed over time?

Over the history we have for it, the NADAC for REXULTI 4 MG TABLET has risen 74.3%. It has been tracked across 546 weekly CMS publications since Apr 20, 2016.

What are the highest and lowest recorded NADAC prices for REXULTI 4 MG TABLET?

Since Apr 20, 2016, the NADAC for REXULTI 4 MG TABLET has ranged from a low of $28.3809 (Apr 20, 2016) to a high of $49.6310 (May 13, 2026), with a median of $39.7070 per EA.

Are there cheaper alternatives to REXULTI 4 MG TABLET?

No other NADAC-published product currently shares the active ingredient and strength of REXULTI 4 MG TABLET in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures REXULTI 4 MG TABLET?

REXULTI 4 MG TABLET (NDC 59148004013) is labeled by Otsuka America Pharmaceutical Inc., and CMS classifies it as a brand product.