Product Information

SYMPROIC 0.2 MG TABLET is a brand product labeled by BioDelivery Sciences International Inc, priced at $16.2516 per EA under NDC 59385004130. Its NADAC has been published 370 times since Jul 24, 2019.

FDA first approved this application on Mar 23, 2017.

SYMPROIC 0.2 MG TABLET

naldemedine
$16.2516per EA

Strength

.2 mg/1

NDC

59385004130

Classification

Brand

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

NALDEMEDINE TOSYLATE

Approval Type

New Drug (NDA)

FDA Application

NDA208854

FDA Approved

3/23/2017

On Market Since

6/14/2019

Pharmacological Classes

Opioid Antagonist
Opioid Antagonists

Price Statistics

The NADAC for SYMPROIC 0.2 MG TABLET has been published 370 times since Jul 24, 2019, and over the history we have for it it has risen 41.5%. The table below summarizes its recorded NADAC range and movement.

Current price$16.2516 per EA
All-time high$16.2809 (May 13, 2026)
All-time low$11.4818 (Jul 24, 2019)
52-week high$16.2809
52-week low$15.5044
Median price$13.9369
Average price$13.7986
Largest weekly change+6.0% (Jan 10, 2024)
Weeks tracked370
Tracking sinceJul 24, 2019

Price History

1W

+0.0%

1M

+0.0%

3M

+0.1%

6M

-0.2%

1Y

+4.8%

3Y

+16.3%

5Y

+28.3%

All

+41.5%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the naldemedine market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Frequently asked questions

What is the NADAC price of SYMPROIC 0.2 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for SYMPROIC 0.2 MG TABLET, manufactured by BioDelivery Sciences International Inc, is $16.2516 per EA (NDC 59385004130), effective Aug 19, 2026.

How has the price of SYMPROIC 0.2 MG TABLET changed over time?

Over the history we have for it, the NADAC for SYMPROIC 0.2 MG TABLET has risen 41.5%. It has been tracked across 370 weekly CMS publications since Jul 24, 2019.

What are the highest and lowest recorded NADAC prices for SYMPROIC 0.2 MG TABLET?

Since Jul 24, 2019, the NADAC for SYMPROIC 0.2 MG TABLET has ranged from a low of $11.4818 (Jul 24, 2019) to a high of $16.2809 (May 13, 2026), with a median of $13.9369 per EA.

Are there cheaper alternatives to SYMPROIC 0.2 MG TABLET?

No other NADAC-published product currently shares the active ingredient and strength of SYMPROIC 0.2 MG TABLET in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures SYMPROIC 0.2 MG TABLET?

SYMPROIC 0.2 MG TABLET (NDC 59385004130) is labeled by BioDelivery Sciences International Inc, and CMS classifies it as a brand product.