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Product Information

MEMANTINE HCL ER 21 MG CAPSULE is a generic product labeled by Aurobindo Pharma Limited, priced at $0.3246 per EA under NDC 59651040630. Its NADAC has been published 217 times since Jun 29, 2022.

FDA first approved this application on Aug 9, 2021. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

MEMANTINE HCL ER 21 MG CAPSULE

MEMANTINE HYDROCHLORIDE
$0.3246per EA

Strength

21 mg/1

NDC

59651040630

Classification

Generic

Dosage Form

CAPSULE, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

MEMANTINE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA214651

FDA Approved

8/9/2021

TE Code

AB

On Market Since

8/9/2021

Pharmacological Classes

N-methyl-D-aspartate Receptor Antagonist
NMDA Receptor Antagonists

Price Statistics

The NADAC for MEMANTINE HCL ER 21 MG CAPSULE has been published 217 times since Jun 29, 2022, and over the history we have for it it has declined 67.4%. The table below summarizes its recorded NADAC range and movement.

Current price$0.3246 per EA
All-time high$1.0807 (Aug 10, 2022)
All-time low$0.3021 (Dec 17, 2025)
52-week high$0.3933
52-week low$0.3021
Median price$0.4575
Average price$0.5303
Largest weekly change+71.8% (Oct 19, 2022)
Weeks tracked217
Tracking sinceJun 29, 2022

Price History

1W

+4.3%

1M

+4.3%

3M

-2.3%

6M

-5.4%

1Y

-17.5%

3Y

-41.8%

5Y

N/A

All

-67.4%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the MEMANTINE HYDROCHLORIDE market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

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Frequently asked questions

What is the NADAC price of MEMANTINE HCL ER 21 MG CAPSULE?

The current National Average Drug Acquisition Cost (NADAC) for MEMANTINE HCL ER 21 MG CAPSULE, manufactured by Aurobindo Pharma Limited, is $0.3246 per EA (NDC 59651040630), effective Aug 19, 2026.

How has the price of MEMANTINE HCL ER 21 MG CAPSULE changed over time?

Over the history we have for it, the NADAC for MEMANTINE HCL ER 21 MG CAPSULE has declined 67.4%. It has been tracked across 217 weekly CMS publications since Jun 29, 2022.

What are the highest and lowest recorded NADAC prices for MEMANTINE HCL ER 21 MG CAPSULE?

Since Jun 29, 2022, the NADAC for MEMANTINE HCL ER 21 MG CAPSULE has ranged from a low of $0.3021 (Dec 17, 2025) to a high of $1.0807 (Aug 10, 2022), with a median of $0.4575 per EA.

Are there cheaper alternatives to MEMANTINE HCL ER 21 MG CAPSULE?

No other NADAC-published product currently shares the active ingredient and strength of MEMANTINE HCL ER 21 MG CAPSULE in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures MEMANTINE HCL ER 21 MG CAPSULE?

MEMANTINE HCL ER 21 MG CAPSULE (NDC 59651040630) is labeled by Aurobindo Pharma Limited, and CMS classifies it as a generic product.