Product Information

DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET is a generic product labeled by ANI Pharmaceuticals, Inc., priced at $0.1386 per EA under NDC 62559049010. Its NADAC has been published 445 times since Feb 14, 2018.

FDA first approved this application before 1982. Its Orange Book therapeutic-equivalence code is AA.

DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET

Diphenoxylate Hydrochloride and Atropine Sulfate
$0.1386per EA
DEA Schedule CV

Strength

.025; 2.5 mg/1; mg/1

NDC

62559049010

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA086727

FDA Approved

Before 1982

TE Code

AA

On Market Since

7/7/2017

Pharmacological Classes

Anticholinergic
Antidiarrheal
Cholinergic Antagonists
Cholinergic Muscarinic Antagonist
Cholinergic Muscarinic Antagonists

Price Statistics

The NADAC for DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET has been published 445 times since Feb 14, 2018, and over the history we have for it it has declined 71.9%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1386 per EA
All-time high$0.5030 (Mar 14, 2018)
All-time low$0.1298 (Nov 20, 2024)
52-week high$0.1837
52-week low$0.1371
Median price$0.2064
Average price$0.2333
Largest weekly change+55.5% (Aug 21, 2024)
Weeks tracked445
Tracking sinceFeb 14, 2018

Price History

1W

+1.1%

1M

+1.1%

3M

-0.0%

6M

-11.2%

1Y

-24.6%

3Y

-23.0%

5Y

-33.2%

All

-71.9%

Generic Alternatives

The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET, manufactured by ANI Pharmaceuticals, Inc., is $0.1386 per EA (NDC 62559049010), effective Aug 19, 2026.

How has the price of DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET changed over time?

Over the history we have for it, the NADAC for DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET has declined 71.9%. It has been tracked across 445 weekly CMS publications since Feb 14, 2018.

What are the highest and lowest recorded NADAC prices for DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET?

Since Feb 14, 2018, the NADAC for DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET has ranged from a low of $0.1298 (Nov 20, 2024) to a high of $0.5030 (Mar 14, 2018), with a median of $0.2064 per EA.

Are there cheaper alternatives to DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET?

4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET?

DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET (NDC 62559049010) is labeled by ANI Pharmaceuticals, Inc., and CMS classifies it as a generic product.