Product Information
DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET is a generic product labeled by ANI Pharmaceuticals, Inc., priced at $0.1389 per EA under NDC 62559049010. Its NADAC has been published 451 times since Feb 14, 2018.
FDA first approved this application before 1982. Its Orange Book therapeutic-equivalence code is AA.
DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET
Diphenoxylate Hydrochloride and Atropine SulfateStrength
.025; 2.5 mg/1; mg/1
Manufacturer
ANI Pharmaceuticals, Inc.NDC
62559049010
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
ATROPINE SULFATE; DIPHENOXYLATE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA086727FDA Approved
Before 1982
TE Code
AA
On Market Since
7/7/2017
Pharmacological Classes
Price Statistics
The NADAC for DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET has been published 451 times since Feb 14, 2018, and over the history we have for it it has declined 71.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1389 per EA |
|---|---|
| All-time high | $0.5030 (Mar 14, 2018) |
| All-time low | $0.1298 (Nov 20, 2024) |
| 52-week high | $0.1761 |
| 52-week low | $0.1371 |
| Median price | $0.2064 |
| Average price | $0.2321 |
| Largest weekly change | +55.5% (Aug 21, 2024) |
| Weeks tracked | 451 |
| Tracking since | Feb 14, 2018 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
ANI Pharmaceuticals, Inc. manufacturer profile
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Drug market
Diphenoxylate Hydrochloride and Atropine Sulfate market comparison
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Therapeutic class
Anticholinergic class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET, manufactured by ANI Pharmaceuticals, Inc., is $0.1389 per EA (NDC 62559049010), effective Sep 30, 2026.
How has the price of DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET changed over time?
Over the history we have for it, the NADAC for DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET has declined 71.9%. It has been tracked across 451 weekly CMS publications since Feb 14, 2018.
What are the highest and lowest recorded NADAC prices for DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET?
Since Feb 14, 2018, the NADAC for DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET has ranged from a low of $0.1298 (Nov 20, 2024) to a high of $0.5030 (Mar 14, 2018), with a median of $0.2064 per EA.
Are there cheaper alternatives to DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET?
4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET?
DIPHENOXYLATE-ATROPINE 2.5-0.025 MG TABLET (NDC 62559049010) is labeled by ANI Pharmaceuticals, Inc., and CMS classifies it as a generic product.