Product Information
CYANOCOBALAMIN 1,000 MCG/ML VL is a generic product labeled by Fresenius Kabi USA, LLC, priced at $1.4739 per ML under NDC 63323004444. Its NADAC has been published 324 times since Jul 22, 2020.
FDA first approved this application before 1982. Its Orange Book therapeutic-equivalence code is AP.
Strength
1000 ug/mL
Manufacturer
Fresenius Kabi USA, LLCNDC
63323004444
Classification
Generic
Dosage Form
INJECTION, SOLUTION
Route
INTRAMUSCULAR; SUBCUTANEOUS
Effective Date
9/23/2026
Active Ingredients
CYANOCOBALAMINApproval Type
Generic (ANDA)
FDA Application
ANDA080557FDA Approved
Before 1982
TE Code
AP
On Market Since
10/18/2000
Pharmacological Classes
Price Statistics
The NADAC for CYANOCOBALAMIN 1,000 MCG/ML VL has been published 324 times since Jul 22, 2020, and over the history we have for it it has declined 56.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.4739 per ML |
|---|---|
| All-time high | $3.5980 (Sep 16, 2020) |
| All-time low | $1.4739 (Sep 23, 2026) |
| 52-week high | $1.6529 |
| 52-week low | $1.4739 |
| Median price | $2.5488 |
| Average price | $2.4093 |
| Largest weekly change | +39.2% (Aug 21, 2024) |
| Weeks tracked | 324 |
| Tracking since | Jul 22, 2020 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 78% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Fresenius Kabi USA, LLC manufacturer profile
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Drug market
CYANOCOBALAMIN market comparison
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Therapeutic class
Vitamin B12 class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of CYANOCOBALAMIN 1,000 MCG/ML VL?
The current National Average Drug Acquisition Cost (NADAC) for CYANOCOBALAMIN 1,000 MCG/ML VL, manufactured by Fresenius Kabi USA, LLC, is $1.4739 per ML (NDC 63323004444), effective Sep 30, 2026.
How has the price of CYANOCOBALAMIN 1,000 MCG/ML VL changed over time?
Over the history we have for it, the NADAC for CYANOCOBALAMIN 1,000 MCG/ML VL has declined 56.1%. It has been tracked across 324 weekly CMS publications since Jul 22, 2020.
What are the highest and lowest recorded NADAC prices for CYANOCOBALAMIN 1,000 MCG/ML VL?
Since Jul 22, 2020, the NADAC for CYANOCOBALAMIN 1,000 MCG/ML VL has ranged from a low of $1.4739 (Sep 23, 2026) to a high of $3.5980 (Sep 16, 2020), with a median of $2.5488 per ML.
Are there cheaper alternatives to CYANOCOBALAMIN 1,000 MCG/ML VL?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CYANOCOBALAMIN 30,000 MCG/30 ML, is $0.3281 per ML — about 78% below CYANOCOBALAMIN 1,000 MCG/ML VL.
Who manufactures CYANOCOBALAMIN 1,000 MCG/ML VL?
CYANOCOBALAMIN 1,000 MCG/ML VL (NDC 63323004444) is labeled by Fresenius Kabi USA, LLC, and CMS classifies it as a generic product.