Cyanocobalamin

36 NDCs across 15 manufacturers|35 Generic,1 Brand

▸ More about this market

The brand product was first FDA-approved before 1982, and the first generic was approved Jan 1, 1982. FDA's Orange Book lists 2 AB-rated (therapeutically equivalent) products for this ingredient.

Cyanocobalamin is available as 36 NDCs from 15 manufacturers (35 generic, 1 brand), with NADAC prices from $0.33 to $2.91 per ML — the most expensive product costs about 8.9× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.

Total NDCs

35G / 1B

Manufacturers

competing in market

Price Spread

$0.33 – $2.91

per ML, 34 of 36 NDCs

7d Activity

18↑6↓12 flat

avg +0.1% WoW · of 36 NDCs

Market Price Trend

Monthly average NADAC per unit, split by generic and brand.

Manufacturer Breakdown

15 manufacturers producing CYANOCOBALAMIN(2 pricing outliers)

Vitruvias Therapeutics Inc.

6 NDCs

$1.1417

avg/unit

Zydus Pharmaceuticals (USA) Inc.

5 NDCs

$1.1187

avg/unit

Meitheal Pharmaceuticals Inc.

4 NDCs

$1.1395

avg/unit

Hikma Pharmaceuticals USA Inc.

4 NDCs

$0.8481

avg/unit

American Regent, Inc.

3 NDCs

$1.4738

avg/unit

Somerset Therapeutics, LLC

3 NDCs

$0.8662

avg/unit

BluePoint Laboratories

2 NDCs

$1.4939

avg/unit

Fresenius Kabi USA, LLC

Padagis Israel Pharmaceuticals Ltd

AuroMedics Pharma LLC

SOLA Pharmaceuticals LLC

Sagent Pharmaceuticals

1 NDC

$1.4939

avg/unit

Drug Portfolio

36 NDCs total, 36 shown

Drug ↕	NDC	Manufacturer ↕	Price	Market Outlier	Class	7d Change ↕	Therapeutic Class
NASCOBAL 500 MCG NASAL SPRAY	49884027082	Endo USA Inc.	$171.7392 per EA	High Outlier	Brand	—	Vitamin B12
CYANOCOBALAMIN 500 MCG SPRAY	45802049184	Padagis Israel Pharmaceuticals Ltd	$98.8340 per EA	High Outlier	Generic	-0.53%	Vitamin B12
CYANOCOBALAMIN 1,000 MCG/ML VL	69680011210	Vitruvias Therapeutics Inc.	$2.9092 per ML	—	Generic	-0.96%	Vitamin B12
CYANOCOBALAMIN 10,000 MCG/10 ML	00517003225	American Regent, Inc.	$2.1337 per ML	—	Generic	—	Vitamin B12
CYANOCOBALAMIN 10,000 MCG/10 ML	70710166407	Zydus Pharmaceuticals (USA) Inc.	$1.9731 per ML	—	Generic	—	Vitamin B12
CYANOCOBALAMIN 1,000 MCG/ML VL	55150036425	AuroMedics Pharma LLC	$1.5580 per ML	—	Generic	—	Vitamin B12
CYANOCOBALAMIN 1,000 MCG/ML VL	68001054260	BluePoint Laboratories	$1.4939 per ML	—	Generic	+1.06%	Vitamin B12
CYANOCOBALAMIN 1,000 MCG/ML VL	68001064060	BluePoint Laboratories	$1.4939 per ML	—	Generic	+1.06%	Vitamin B12
CYANOCOBALAMIN 1,000 MCG/ML VL	69680011225	Vitruvias Therapeutics Inc.	$1.4939 per ML	—	Generic	+1.06%	Vitamin B12
CYANOCOBALAMIN 1,000 MCG/ML VL	70069000510	Somerset Therapeutics, LLC	$1.4939 per ML	—	Generic	+1.06%	Vitamin B12
CYANOCOBALAMIN 1,000 MCG/ML VL	72603065025	NorthStar Rx LLC	$1.4939 per ML	—	Generic	+1.06%	Vitamin B12
CYANOCOBALAMIN 1,000 MCG/ML VL	70512084025	SOLA Pharmaceuticals LLC	$1.4939 per ML	—	Generic	+1.06%	Vitamin B12
CYANOCOBALAMIN 1,000 MCG/ML VL	70756063525	Lifestar Pharma LLC	$1.4939 per ML	—	Generic	+1.06%	Vitamin B12
CYANOCOBALAMIN 1,000 MCG/ML VL	71288030302	Meitheal Pharmaceuticals Inc.	$1.4939 per ML	—	Generic	+1.06%	Vitamin B12
CYANOCOBALAMIN 1,000 MCG/ML VL	71288030392	Meitheal Pharmaceuticals Inc.	$1.4939 per ML	—	Generic	+1.06%	Vitamin B12
CYANOCOBALAMIN 1,000 MCG/ML VL	00143962125	Hikma Pharmaceuticals USA Inc.	$1.4939 per ML	—	Generic	+1.06%	Vitamin B12
CYANOCOBALAMIN 1,000 MCG/ML VL	00517003125	American Regent, Inc.	$1.4939 per ML	—	Generic	+1.06%	Vitamin B12
CYANOCOBALAMIN 1,000 MCG/ML VL	25021050201	Sagent Pharmaceuticals	$1.4939 per ML	—	Generic	+1.06%	Vitamin B12
CYANOCOBALAMIN 1,000 MCG/ML VL	63323004401	Fresenius Kabi USA, LLC	$1.4939 per ML	—	Generic	+1.06%	Vitamin B12
CYANOCOBALAMIN 1,000 MCG/ML VL	63323004444	Fresenius Kabi USA, LLC	$1.4939 per ML	—	Generic	+1.06%	Vitamin B12
CYANOCOBALAMIN 1,000 MCG/ML VL	70710166307	Zydus Pharmaceuticals (USA) Inc.	$1.4915 per ML	—	Generic	—	Vitamin B12
CYANOCOBALAMIN 10,000 MCG/10 ML	70710166406	Zydus Pharmaceuticals (USA) Inc.	$0.8188 per ML	—	Generic	—	Vitamin B12
CYANOCOBALAMIN 30,000 MCG/30 ML	71288030230	Meitheal Pharmaceuticals Inc.	$0.7938 per ML	—	Generic	+1.00%	Vitamin B12
CYANOCOBALAMIN 30,000 MCG/30 ML	69680012130	Vitruvias Therapeutics Inc.	$0.7938 per ML	—	Generic	+1.00%	Vitamin B12
CYANOCOBALAMIN 30,000 MCG/30 ML	00517013001	American Regent, Inc.	$0.7938 per ML	—	Generic	+1.00%	Vitamin B12
CYANOCOBALAMIN 30,000 MCG/30 ML	00143961901	Hikma Pharmaceuticals USA Inc.	$0.7938 per ML	—	Generic	+1.00%	Vitamin B12
CYANOCOBALAMIN 10,000 MCG/10 ML	00143962010	Hikma Pharmaceuticals USA Inc.	$0.7765 per ML	—	Generic	-3.91%	Vitamin B12
CYANOCOBALAMIN 10,000 MCG/10 ML	71288030111	Meitheal Pharmaceuticals Inc.	$0.7765 per ML	—	Generic	-3.91%	Vitamin B12
CYANOCOBALAMIN 10,000 MCG/10 ML	69680011399	Vitruvias Therapeutics Inc.	$0.7765 per ML	—	Generic	-3.91%	Vitamin B12
CYANOCOBALAMIN 10,000 MCG/10 ML	70069017210	Somerset Therapeutics, LLC	$0.7765 per ML	—	Generic	-3.91%	Vitamin B12
CYANOCOBALAMIN 30,000 MCG/30 ML	70710166501	Zydus Pharmaceuticals (USA) Inc.	$0.7612 per ML	—	Generic	—	Vitamin B12
CYANOCOBALAMIN 30,000 MCG/30 ML	69680012105	Vitruvias Therapeutics Inc.	$0.5487 per ML	—	Generic	—	Vitamin B12
CYANOCOBALAMIN 30,000 MCG/30 ML	70710166505	Zydus Pharmaceuticals (USA) Inc.	$0.5487 per ML	—	Generic	—	Vitamin B12
CYANOCOBALAMIN 30,000 MCG/30 ML	00143961910	Hikma Pharmaceuticals USA Inc.	$0.3281 per ML	—	Generic	—	Vitamin B12
CYANOCOBALAMIN 30,000 MCG/30 ML	69680012110	Vitruvias Therapeutics Inc.	$0.3281 per ML	—	Generic	—	Vitamin B12
CYANOCOBALAMIN 30,000 MCG/30 ML	70069017110	Somerset Therapeutics, LLC	$0.3281 per ML	—	Generic	—	Vitamin B12

Frequently Asked Questions

When did Cyanocobalamin become available as a generic?

FDA approved the first generic Cyanocobalamin (ANDA) on Jan 1, 1982. The Orange Book currently lists 2 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.

How many Cyanocobalamin products are on the market?

The Cyanocobalamin drug market contains 36 NDCs from 15 manufacturers — 35 generic and 1 brand product.

What is the price range for Cyanocobalamin?

NADAC reference prices for Cyanocobalamin range from $0.3281 to $2.9092 per ML — the most expensive product costs about 8.9× the cheapest. 2 additional products are priced per different units (e.g. liquids per ML) and aren't directly comparable.

Which manufacturers make Cyanocobalamin?

15 manufacturers list Cyanocobalamin in NADAC. Ranked by number of NDCs, the largest are Vitruvias Therapeutics Inc. (6), Zydus Pharmaceuticals (USA) Inc. (5), Meitheal Pharmaceuticals Inc. (4), Hikma Pharmaceuticals USA Inc. (4), American Regent, Inc. (3).

How has the price of Cyanocobalamin changed recently?

Over the past 7 days, 18 Cyanocobalamin NDCs rose and 6 fell, with a market-wide average change of +0.1%.