Product Information
PROPAFENONE HCL ER 425 MG CAP is a generic product labeled by Strides Pharma Inc., priced at $0.5650 per EA under NDC 64380018601. Its NADAC has been published 123 times since Apr 17, 2024.
FDA first approved this application on Oct 18, 2010. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
425 mg/1
Manufacturer
Strides Pharma Inc.NDC
64380018601
Classification
Generic
Dosage Form
CAPSULE, EXTENDED RELEASE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
PROPAFENONE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA078540FDA Approved
10/18/2010
TE Code
AB
On Market Since
4/4/2022
Pharmacological Classes
Price Statistics
The NADAC for PROPAFENONE HCL ER 425 MG CAP has been published 123 times since Apr 17, 2024, and over the history we have for it it has declined 59.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.5650 per EA |
|---|---|
| All-time high | $1.3963 (May 15, 2024) |
| All-time low | $0.5637 (Jul 22, 2026) |
| 52-week high | $1.1142 |
| 52-week low | $0.5637 |
| Median price | $0.9917 |
| Average price | $0.9714 |
| Largest weekly change | -26.2% (Jun 17, 2026) |
| Weeks tracked | 123 |
| Tracking since | Apr 17, 2024 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of PROPAFENONE HCL ER 425 MG CAP?
The current National Average Drug Acquisition Cost (NADAC) for PROPAFENONE HCL ER 425 MG CAP, manufactured by Strides Pharma Inc., is $0.5650 per EA (NDC 64380018601), effective Aug 19, 2026.
How has the price of PROPAFENONE HCL ER 425 MG CAP changed over time?
Over the history we have for it, the NADAC for PROPAFENONE HCL ER 425 MG CAP has declined 59.5%. It has been tracked across 123 weekly CMS publications since Apr 17, 2024.
What are the highest and lowest recorded NADAC prices for PROPAFENONE HCL ER 425 MG CAP?
Since Apr 17, 2024, the NADAC for PROPAFENONE HCL ER 425 MG CAP has ranged from a low of $0.5637 (Jul 22, 2026) to a high of $1.3963 (May 15, 2024), with a median of $0.9917 per EA.
Are there cheaper alternatives to PROPAFENONE HCL ER 425 MG CAP?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as PROPAFENONE HCL ER 425 MG CAP in a comparable dosage form, but none are currently priced below it.
Who manufactures PROPAFENONE HCL ER 425 MG CAP?
PROPAFENONE HCL ER 425 MG CAP (NDC 64380018601) is labeled by Strides Pharma Inc., and CMS classifies it as a generic product.