Product Information

PROPAFENONE HCL 225 MG TAB is a generic product labeled by Strides Pharma Inc., priced at $0.1929 per EA under NDC 64380026801. Its NADAC has been published 60 times since Jul 2, 2025.

FDA first approved this application on Oct 17, 2002. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

PROPAFENONE HCL 225 MG TAB

PROPAFENONE HYDROCHLORIDE
$0.1929per EA

Strength

225 mg/1

NDC

64380026801

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

PROPAFENONE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA075938

FDA Approved

10/17/2002

TE Code

AB

On Market Since

5/5/2025

Pharmacological Classes

Price Statistics

The NADAC for PROPAFENONE HCL 225 MG TAB has been published 60 times since Jul 2, 2025, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.

Current price$0.1929 per EA
All-time high$0.2092 (Oct 15, 2025)
All-time low$0.1897 (Jul 22, 2026)
52-week high$0.2092
52-week low$0.1897
Median price$0.2011
Average price$0.2003
Largest weekly change+5.6% (Aug 20, 2025)
Weeks tracked60
Tracking sinceJul 2, 2025

Price History

1W

+1.7%

1M

+1.7%

3M

-0.7%

6M

-6.8%

1Y

-7.7%

3Y

N/A

5Y

N/A

All

+0.9%

Generic Alternatives

The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of PROPAFENONE HCL 225 MG TAB?

The current National Average Drug Acquisition Cost (NADAC) for PROPAFENONE HCL 225 MG TAB, manufactured by Strides Pharma Inc., is $0.1929 per EA (NDC 64380026801), effective Aug 19, 2026.

How has the price of PROPAFENONE HCL 225 MG TAB changed over time?

Over the history we have for it, the NADAC for PROPAFENONE HCL 225 MG TAB has held within roughly two percent of its current level. It has been tracked across 60 weekly CMS publications since Jul 2, 2025.

What are the highest and lowest recorded NADAC prices for PROPAFENONE HCL 225 MG TAB?

Since Jul 2, 2025, the NADAC for PROPAFENONE HCL 225 MG TAB has ranged from a low of $0.1897 (Jul 22, 2026) to a high of $0.2092 (Oct 15, 2025), with a median of $0.2011 per EA.

Are there cheaper alternatives to PROPAFENONE HCL 225 MG TAB?

2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as PROPAFENONE HCL 225 MG TAB in a comparable dosage form, but none are currently priced below it.

Who manufactures PROPAFENONE HCL 225 MG TAB?

PROPAFENONE HCL 225 MG TAB (NDC 64380026801) is labeled by Strides Pharma Inc., and CMS classifies it as a generic product.