Product Information
ZILEUTON ER 600 MG TABLET is a generic product labeled by Rising Pharma Holdings Inc., priced at $2.0493 per EA under NDC 64980020612. Its NADAC has been published 355 times since Jul 18, 2018.
FDA first approved this application on Mar 17, 2017. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
600 mg/1
Manufacturer
Rising Pharma Holdings Inc.NDC
64980020612
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
ZILEUTONApproval Type
Generic (ANDA)
FDA Application
ANDA204929FDA Approved
3/17/2017
TE Code
AB
On Market Since
3/21/2017
Pharmacological Classes
Price Statistics
The NADAC for ZILEUTON ER 600 MG TABLET has been published 355 times since Jul 18, 2018, and over the history we have for it it has declined 91.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.0493 per EA |
|---|---|
| All-time high | $25.1068 (Oct 10, 2018) |
| All-time low | $1.9211 (Jun 17, 2026) |
| 52-week high | $3.0625 |
| 52-week low | $1.9211 |
| Median price | $10.0166 |
| Average price | $11.9670 |
| Largest weekly change | -36.1% (Apr 17, 2024) |
| Weeks tracked | 355 |
| Tracking since | Jul 18, 2018 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
Rising Pharma Holdings Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Zileuton market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of ZILEUTON ER 600 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for ZILEUTON ER 600 MG TABLET, manufactured by Rising Pharma Holdings Inc., is $2.0493 per EA (NDC 64980020612), effective Sep 30, 2026.
How has the price of ZILEUTON ER 600 MG TABLET changed over time?
Over the history we have for it, the NADAC for ZILEUTON ER 600 MG TABLET has declined 91.8%. It has been tracked across 355 weekly CMS publications since Jul 18, 2018.
What are the highest and lowest recorded NADAC prices for ZILEUTON ER 600 MG TABLET?
Since Jul 18, 2018, the NADAC for ZILEUTON ER 600 MG TABLET has ranged from a low of $1.9211 (Jun 17, 2026) to a high of $25.1068 (Oct 10, 2018), with a median of $10.0166 per EA.
Are there cheaper alternatives to ZILEUTON ER 600 MG TABLET?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ZILEUTON ER 600 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures ZILEUTON ER 600 MG TABLET?
ZILEUTON ER 600 MG TABLET (NDC 64980020612) is labeled by Rising Pharma Holdings Inc., and CMS classifies it as a generic product.