Product Information
BRIMONIDINE-TIMOLOL 0.2%-0.5% is a generic product labeled by Caplin Steriles Limited, priced at $2.8820 per ML under NDC 65145016201. Its NADAC has been published 38 times since Oct 8, 2025.
Strength
2; 5 mg/mL; mg/mL
Manufacturer
Caplin Steriles LimitedNDC
65145016201
Classification
Generic
Dosage Form
SOLUTION
Route
OPHTHALMIC
Last Updated
6/17/2026
Active Ingredients
BRIMONIDINE TARTRATE; TIMOLOL MALEATEApproval Type
Generic (ANDA)
FDA Application
ANDA219093On Market Since
3/10/2025
Pharmacological Classes
Price Statistics
The NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has been published 38 times since Oct 8, 2025, and over the history we have for it it has declined 35.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.8820 per ML |
|---|---|
| All-time high | $4.4337 (Oct 15, 2025) |
| All-time low | $2.8820 (Jun 17, 2026) |
| 52-week high | $4.4337 |
| 52-week low | $2.8820 |
| Median price | $3.3213 |
| Average price | $3.4621 |
| Largest weekly change | -14.1% (Oct 22, 2025) |
| Weeks tracked | 38 |
| Tracking since | Oct 8, 2025 |
Generic Alternatives
The matcher finds 8 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 8 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 27% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of BRIMONIDINE-TIMOLOL 0.2%-0.5%?
The current National Average Drug Acquisition Cost (NADAC) for BRIMONIDINE-TIMOLOL 0.2%-0.5%, manufactured by Caplin Steriles Limited, is $2.8820 per ML (NDC 65145016201), effective Jun 24, 2026.
How has the price of BRIMONIDINE-TIMOLOL 0.2%-0.5% changed over time?
Over the history we have for it, the NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has declined 35.0%. It has been tracked across 38 weekly CMS publications since Oct 8, 2025.
What are the highest and lowest recorded NADAC prices for BRIMONIDINE-TIMOLOL 0.2%-0.5%?
Since Oct 8, 2025, the NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has ranged from a low of $2.8820 (Jun 17, 2026) to a high of $4.4337 (Oct 15, 2025), with a median of $3.3213 per ML.
Are there cheaper alternatives to BRIMONIDINE-TIMOLOL 0.2%-0.5%?
Yes. 8 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, BRIMONIDINE-TIMOLOL 0.2%-0.5%, is $2.1018 per ML — about 27% below BRIMONIDINE-TIMOLOL 0.2%-0.5%.
Who manufactures BRIMONIDINE-TIMOLOL 0.2%-0.5%?
BRIMONIDINE-TIMOLOL 0.2%-0.5% (NDC 65145016201) is labeled by Caplin Steriles Limited, and CMS classifies it as a generic product.
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