Product Information
BRIMONIDINE-TIMOLOL 0.2%-0.5% is a generic product labeled by Caplin Steriles Limited, priced at $2.1018 per ML under NDC 65145016401. Its NADAC has been published 38 times since Oct 8, 2025.
Strength
2; 5 mg/mL; mg/mL
Manufacturer
Caplin Steriles LimitedNDC
65145016401
Classification
Generic
Dosage Form
SOLUTION
Route
OPHTHALMIC
Last Updated
6/17/2026
Active Ingredients
BRIMONIDINE TARTRATE; TIMOLOL MALEATEApproval Type
Generic (ANDA)
FDA Application
ANDA219093On Market Since
3/10/2025
Pharmacological Classes
Price Statistics
The NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has been published 38 times since Oct 8, 2025, and over the history we have for it it has declined 69.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.1018 per ML |
|---|---|
| All-time high | $6.8975 (Oct 15, 2025) |
| All-time low | $2.1018 (Jun 17, 2026) |
| 52-week high | $6.8975 |
| 52-week low | $2.1018 |
| Median price | $3.0383 |
| Average price | $3.8083 |
| Largest weekly change | -35.8% (Dec 17, 2025) |
| Weeks tracked | 38 |
| Tracking since | Oct 8, 2025 |
Generic Alternatives
The matcher finds 8 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 8 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of BRIMONIDINE-TIMOLOL 0.2%-0.5%?
The current National Average Drug Acquisition Cost (NADAC) for BRIMONIDINE-TIMOLOL 0.2%-0.5%, manufactured by Caplin Steriles Limited, is $2.1018 per ML (NDC 65145016401), effective Jun 24, 2026.
How has the price of BRIMONIDINE-TIMOLOL 0.2%-0.5% changed over time?
Over the history we have for it, the NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has declined 69.5%. It has been tracked across 38 weekly CMS publications since Oct 8, 2025.
What are the highest and lowest recorded NADAC prices for BRIMONIDINE-TIMOLOL 0.2%-0.5%?
Since Oct 8, 2025, the NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has ranged from a low of $2.1018 (Jun 17, 2026) to a high of $6.8975 (Oct 15, 2025), with a median of $3.0383 per ML.
Are there cheaper alternatives to BRIMONIDINE-TIMOLOL 0.2%-0.5%?
8 NADAC-published products share the same active ingredient, strength, and dosage form as BRIMONIDINE-TIMOLOL 0.2%-0.5%, but none are currently priced below it.
Who manufactures BRIMONIDINE-TIMOLOL 0.2%-0.5%?
BRIMONIDINE-TIMOLOL 0.2%-0.5% (NDC 65145016401) is labeled by Caplin Steriles Limited, and CMS classifies it as a generic product.
Related Drugs
Same classification