Product Information

DIVALPROEX SOD ER 500 MG TAB is a generic product labeled by Amneal Pharmaceuticals LLC, priced at $0.1943 per EA under NDC 65162075750. Its NADAC has been published 583 times since Aug 5, 2015.

FDA first approved this application on May 29, 2015. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

DIVALPROEX SOD ER 500 MG TAB

Divalproex Sodium
$0.1943per EA

Strength

500 mg/1

NDC

65162075750

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Effective Date

9/23/2026

Active Ingredients

DIVALPROEX SODIUM

Approval Type

Generic (ANDA)

FDA Application

ANDA203730

FDA Approved

5/29/2015

TE Code

AB

On Market Since

6/1/2015

Pharmacological Classes

Anti-epileptic Agent
Decreased Central Nervous System Disorganized Electrical Activity
Mood Stabilizer

Price Statistics

The NADAC for DIVALPROEX SOD ER 500 MG TAB has been published 583 times since Aug 5, 2015, and over the history we have for it it has declined 86.5%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1943 per EA
All-time high$1.4429 (Aug 12, 2015)
All-time low$0.1508 (Nov 20, 2024)
52-week high$0.1943
52-week low$0.1679
Median price$0.2561
Average price$0.3906
Largest weekly change-24.0% (Nov 20, 2024)
Weeks tracked583
Tracking sinceAug 5, 2015

Price History

1W

0.0%

1M

+5.8%

3M

+5.7%

6M

+11.6%

1Y

+3.4%

3Y

-1.1%

5Y

-18.9%

All

-86.5%

Generic Alternatives

The matcher finds 12 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 37% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Continue researching this drug

Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.

Frequently asked questions

What is the NADAC price of DIVALPROEX SOD ER 500 MG TAB?

The current National Average Drug Acquisition Cost (NADAC) for DIVALPROEX SOD ER 500 MG TAB, manufactured by Amneal Pharmaceuticals LLC, is $0.1943 per EA (NDC 65162075750), effective Sep 30, 2026.

How has the price of DIVALPROEX SOD ER 500 MG TAB changed over time?

Over the history we have for it, the NADAC for DIVALPROEX SOD ER 500 MG TAB has declined 86.5%. It has been tracked across 583 weekly CMS publications since Aug 5, 2015.

What are the highest and lowest recorded NADAC prices for DIVALPROEX SOD ER 500 MG TAB?

Since Aug 5, 2015, the NADAC for DIVALPROEX SOD ER 500 MG TAB has ranged from a low of $0.1508 (Nov 20, 2024) to a high of $1.4429 (Aug 12, 2015), with a median of $0.2561 per EA.

Are there cheaper alternatives to DIVALPROEX SOD ER 500 MG TAB?

Yes. 12 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DIVALPROEX SOD DR 500 MG TAB, is $0.1228 per EA — about 37% below DIVALPROEX SOD ER 500 MG TAB.

Who manufactures DIVALPROEX SOD ER 500 MG TAB?

DIVALPROEX SOD ER 500 MG TAB (NDC 65162075750) is labeled by Amneal Pharmaceuticals LLC, and CMS classifies it as a generic product.