Product Information
MEMANTINE HCL ER 21 MG CAPSULE is a generic product labeled by Amneal Pharmaceuticals LLC, priced at $0.3246 per EA under NDC 65162078403. Its NADAC has been published 431 times since May 23, 2018.
FDA first approved this application on Oct 12, 2016. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
21 mg/1
Manufacturer
Amneal Pharmaceuticals LLCNDC
65162078403
Classification
Generic
Dosage Form
CAPSULE, EXTENDED RELEASE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
MEMANTINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA205825FDA Approved
10/12/2016
TE Code
AB
On Market Since
12/22/2017
Pharmacological Classes
Price Statistics
The NADAC for MEMANTINE HCL ER 21 MG CAPSULE has been published 431 times since May 23, 2018, and over the history we have for it it has declined 94.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3246 per EA |
|---|---|
| All-time high | $6.8777 (Jul 11, 2018) |
| All-time low | $0.3021 (Dec 17, 2025) |
| 52-week high | $0.3933 |
| 52-week low | $0.3021 |
| Median price | $0.9633 |
| Average price | $1.5611 |
| Largest weekly change | +71.8% (Oct 19, 2022) |
| Weeks tracked | 431 |
| Tracking since | May 23, 2018 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Memantine Hydrochloride market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of MEMANTINE HCL ER 21 MG CAPSULE?
The current National Average Drug Acquisition Cost (NADAC) for MEMANTINE HCL ER 21 MG CAPSULE, manufactured by Amneal Pharmaceuticals LLC, is $0.3246 per EA (NDC 65162078403), effective Aug 19, 2026.
How has the price of MEMANTINE HCL ER 21 MG CAPSULE changed over time?
Over the history we have for it, the NADAC for MEMANTINE HCL ER 21 MG CAPSULE has declined 94.5%. It has been tracked across 431 weekly CMS publications since May 23, 2018.
What are the highest and lowest recorded NADAC prices for MEMANTINE HCL ER 21 MG CAPSULE?
Since May 23, 2018, the NADAC for MEMANTINE HCL ER 21 MG CAPSULE has ranged from a low of $0.3021 (Dec 17, 2025) to a high of $6.8777 (Jul 11, 2018), with a median of $0.9633 per EA.
Are there cheaper alternatives to MEMANTINE HCL ER 21 MG CAPSULE?
No other NADAC-published product currently shares the active ingredient and strength of MEMANTINE HCL ER 21 MG CAPSULE in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures MEMANTINE HCL ER 21 MG CAPSULE?
MEMANTINE HCL ER 21 MG CAPSULE (NDC 65162078403) is labeled by Amneal Pharmaceuticals LLC, and CMS classifies it as a generic product.