Product Information

RELISTOR 12 MG/0.6 ML VIAL is a brand product labeled by Salix Pharmaceuticals Inc., priced at $271.5833 per ML under NDC 65649055102. Its NADAC has been published 293 times since Nov 28, 2013.

FDA first approved this application on Apr 24, 2008.

RELISTOR 12 MG/0.6 ML VIAL

Methylnaltrexone bromide
$271.5833per ML

Strength

12 mg/.6mL

NDC

65649055102

Classification

Brand

Dosage Form

INJECTION, SOLUTION

Route

SUBCUTANEOUS

Effective Date

9/17/2025

Active Ingredients

METHYLNALTREXONE BROMIDE

Approval Type

New Drug (NDA)

FDA Application

NDA021964

FDA Approved

4/24/2008

On Market Since

4/24/2008

Pharmacological Classes

Opioid Antagonist
Opioid Antagonists
Quaternary Ammonium Compounds

Price Statistics

The NADAC for RELISTOR 12 MG/0.6 ML VIAL has been published 293 times since Nov 28, 2013, and over the history we have for it it has risen 178.3%. The table below summarizes its recorded NADAC range and movement.

Current price$271.5833 per ML
All-time high$271.5833 (Oct 1, 2025)
All-time low$97.5858 (Nov 28, 2013)
52-week high$271.5833
52-week low$271.5833
Median price$159.4361
Average price$189.8302
Largest weekly change+44.6% (Dec 21, 2022)
Weeks tracked293
Tracking sinceNov 28, 2013

Price History

1W

N/A

1M

N/A

3M

N/A

6M

N/A

1Y

0.0%

3Y

+11.1%

5Y

+70.3%

All

+178.3%

Last surveyed Oct 1, 2025 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 0% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 0%

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of RELISTOR 12 MG/0.6 ML VIAL?

The current National Average Drug Acquisition Cost (NADAC) for RELISTOR 12 MG/0.6 ML VIAL, manufactured by Salix Pharmaceuticals Inc., is $271.5833 per ML (NDC 65649055102), effective Oct 1, 2025.

How has the price of RELISTOR 12 MG/0.6 ML VIAL changed over time?

Over the history we have for it, the NADAC for RELISTOR 12 MG/0.6 ML VIAL has risen 178.3%. It has been tracked across 293 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for RELISTOR 12 MG/0.6 ML VIAL?

Since Nov 28, 2013, the NADAC for RELISTOR 12 MG/0.6 ML VIAL has ranged from a low of $97.5858 (Nov 28, 2013) to a high of $271.5833 (Oct 1, 2025), with a median of $159.4361 per ML.

Are there cheaper alternatives to RELISTOR 12 MG/0.6 ML VIAL?

Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, RELISTOR 12 MG/0.6 ML SYRINGE, is $271.2074 per ML — about 0% below RELISTOR 12 MG/0.6 ML VIAL.

Who manufactures RELISTOR 12 MG/0.6 ML VIAL?

RELISTOR 12 MG/0.6 ML VIAL (NDC 65649055102) is labeled by Salix Pharmaceuticals Inc., and CMS classifies it as a brand product.