Product Information
RELISTOR 12 MG/0.6 ML SYRINGE is a brand product labeled by Salix Pharmaceuticals Inc., priced at $271.2074 per ML under NDC 65649055107. Its NADAC has been published 125 times since May 18, 2016.
FDA first approved this application on Apr 24, 2008.
Strength
12 mg/.6mL
Manufacturer
Salix Pharmaceuticals Inc.NDC
65649055107
Classification
Brand
Dosage Form
INJECTION, SOLUTION
Route
SUBCUTANEOUS
Effective Date
1/1/2025
Active Ingredients
METHYLNALTREXONE BROMIDEApproval Type
New Drug (NDA)
FDA Application
NDA021964FDA Approved
4/24/2008
On Market Since
4/24/2008
Pharmacological Classes
Price Statistics
The NADAC for RELISTOR 12 MG/0.6 ML SYRINGE has been published 125 times since May 18, 2016, and over the history we have for it it has risen 69.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $271.2074 per ML |
|---|---|
| All-time high | $271.2074 (Oct 1, 2025) |
| All-time low | $160.0028 (May 18, 2016) |
| 52-week high | $271.2074 |
| 52-week low | $271.2074 |
| Median price | $255.8409 |
| Average price | $216.9407 |
| Largest weekly change | +59.6% (Jun 19, 2024) |
| Weeks tracked | 125 |
| Tracking since | May 18, 2016 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
0.0%
3Y
+69.5%
5Y
+69.5%
All
+69.5%
Last surveyed Oct 1, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of RELISTOR 12 MG/0.6 ML SYRINGE?
The current National Average Drug Acquisition Cost (NADAC) for RELISTOR 12 MG/0.6 ML SYRINGE, manufactured by Salix Pharmaceuticals Inc., is $271.2074 per ML (NDC 65649055107), effective Oct 1, 2025.
How has the price of RELISTOR 12 MG/0.6 ML SYRINGE changed over time?
Over the history we have for it, the NADAC for RELISTOR 12 MG/0.6 ML SYRINGE has risen 69.5%. It has been tracked across 125 weekly CMS publications since May 18, 2016.
What are the highest and lowest recorded NADAC prices for RELISTOR 12 MG/0.6 ML SYRINGE?
Since May 18, 2016, the NADAC for RELISTOR 12 MG/0.6 ML SYRINGE has ranged from a low of $160.0028 (May 18, 2016) to a high of $271.2074 (Oct 1, 2025), with a median of $255.8409 per ML.
Are there cheaper alternatives to RELISTOR 12 MG/0.6 ML SYRINGE?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as RELISTOR 12 MG/0.6 ML SYRINGE in a comparable dosage form, but none are currently priced below it.
Who manufactures RELISTOR 12 MG/0.6 ML SYRINGE?
RELISTOR 12 MG/0.6 ML SYRINGE (NDC 65649055107) is labeled by Salix Pharmaceuticals Inc., and CMS classifies it as a brand product.