Product Information
RELISTOR 12 MG/0.6 ML SYRINGE is a brand product labeled by Salix Pharmaceuticals Inc., priced at $272.6830 per ML under NDC 65649055103. Its NADAC has been published 588 times since Nov 28, 2013.
FDA first approved this application on Apr 24, 2008.
Strength
12 mg/.6mL
Manufacturer
Salix Pharmaceuticals Inc.NDC
65649055103
Classification
Brand
Dosage Form
INJECTION, SOLUTION
Route
SUBCUTANEOUS
Effective Date
9/17/2025
Active Ingredients
METHYLNALTREXONE BROMIDEApproval Type
New Drug (NDA)
FDA Application
NDA021964FDA Approved
4/24/2008
On Market Since
4/24/2008
Pharmacological Classes
Price Statistics
The NADAC for RELISTOR 12 MG/0.6 ML SYRINGE has been published 588 times since Nov 28, 2013, and over the history we have for it it has risen 184.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $272.6830 per ML |
|---|---|
| All-time high | $272.8943 (Sep 10, 2025) |
| All-time low | $95.9067 (Nov 28, 2013) |
| 52-week high | $272.8943 |
| 52-week low | $272.6830 |
| Median price | $199.4424 |
| Average price | $192.6783 |
| Largest weekly change | +38.8% (Sep 23, 2015) |
| Weeks tracked | 588 |
| Tracking since | Nov 28, 2013 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
-0.1%
3Y
+10.8%
5Y
+26.7%
All
+184.3%
Last surveyed Oct 1, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 1% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of RELISTOR 12 MG/0.6 ML SYRINGE?
The current National Average Drug Acquisition Cost (NADAC) for RELISTOR 12 MG/0.6 ML SYRINGE, manufactured by Salix Pharmaceuticals Inc., is $272.6830 per ML (NDC 65649055103), effective Oct 1, 2025.
How has the price of RELISTOR 12 MG/0.6 ML SYRINGE changed over time?
Over the history we have for it, the NADAC for RELISTOR 12 MG/0.6 ML SYRINGE has risen 184.3%. It has been tracked across 588 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for RELISTOR 12 MG/0.6 ML SYRINGE?
Since Nov 28, 2013, the NADAC for RELISTOR 12 MG/0.6 ML SYRINGE has ranged from a low of $95.9067 (Nov 28, 2013) to a high of $272.8943 (Sep 10, 2025), with a median of $199.4424 per ML.
Are there cheaper alternatives to RELISTOR 12 MG/0.6 ML SYRINGE?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, RELISTOR 12 MG/0.6 ML SYRINGE, is $271.2074 per ML — about 1% below RELISTOR 12 MG/0.6 ML SYRINGE.
Who manufactures RELISTOR 12 MG/0.6 ML SYRINGE?
RELISTOR 12 MG/0.6 ML SYRINGE (NDC 65649055103) is labeled by Salix Pharmaceuticals Inc., and CMS classifies it as a brand product.