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Product Information

RELISTOR 8 MG/0.4 ML SYRINGE is a brand product labeled by Salix Pharmaceuticals Inc., priced at $409.7653 per ML under NDC 65649055204. Its NADAC has been published 220 times since Nov 19, 2014.

FDA first approved this application on Apr 24, 2008.

RELISTOR 8 MG/0.4 ML SYRINGE

Methylnaltrexone bromide
$409.7653per ML

Strength

8 mg/.4mL

NDC

65649055204

Classification

Brand

Dosage Form

INJECTION, SOLUTION

Route

SUBCUTANEOUS

Effective Date

1/1/2025

Active Ingredients

METHYLNALTREXONE BROMIDE

Approval Type

New Drug (NDA)

FDA Application

NDA021964

FDA Approved

4/24/2008

On Market Since

4/24/2008

Pharmacological Classes

Opioid Antagonist
Opioid Antagonists
Quaternary Ammonium Compounds

Price Statistics

The NADAC for RELISTOR 8 MG/0.4 ML SYRINGE has been published 220 times since Nov 19, 2014, and over the history we have for it it has risen 158.7%. The table below summarizes its recorded NADAC range and movement.

Current price$409.7653 per ML
All-time high$409.7653 (Oct 1, 2025)
All-time low$158.3893 (Nov 19, 2014)
52-week high$409.7653
52-week low$409.7653
Median price$264.8895
Average price$284.3613
Largest weekly change+45.7% (May 22, 2024)
Weeks tracked220
Tracking sinceNov 19, 2014

Price History

1W

N/A

1M

N/A

3M

N/A

6M

N/A

1Y

0.0%

3Y

+54.7%

5Y

+54.7%

All

+158.7%

Last surveyed Oct 1, 2025 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Methylnaltrexone bromide market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

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Frequently asked questions

What is the NADAC price of RELISTOR 8 MG/0.4 ML SYRINGE?

The current National Average Drug Acquisition Cost (NADAC) for RELISTOR 8 MG/0.4 ML SYRINGE, manufactured by Salix Pharmaceuticals Inc., is $409.7653 per ML (NDC 65649055204), effective Oct 1, 2025.

How has the price of RELISTOR 8 MG/0.4 ML SYRINGE changed over time?

Over the history we have for it, the NADAC for RELISTOR 8 MG/0.4 ML SYRINGE has risen 158.7%. It has been tracked across 220 weekly CMS publications since Nov 19, 2014.

What are the highest and lowest recorded NADAC prices for RELISTOR 8 MG/0.4 ML SYRINGE?

Since Nov 19, 2014, the NADAC for RELISTOR 8 MG/0.4 ML SYRINGE has ranged from a low of $158.3893 (Nov 19, 2014) to a high of $409.7653 (Oct 1, 2025), with a median of $264.8895 per ML.

Are there cheaper alternatives to RELISTOR 8 MG/0.4 ML SYRINGE?

No other NADAC-published product currently shares the active ingredient and strength of RELISTOR 8 MG/0.4 ML SYRINGE in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures RELISTOR 8 MG/0.4 ML SYRINGE?

RELISTOR 8 MG/0.4 ML SYRINGE (NDC 65649055204) is labeled by Salix Pharmaceuticals Inc., and CMS classifies it as a brand product.