Product Information

LYBALVI 5-10 MG TABLET is a brand product labeled by Alkermes, Inc., priced at $55.2056 per EA under NDC 65757065142. Its NADAC has been published 223 times since May 18, 2022.

FDA first approved this application on May 28, 2021.

LYBALVI 5-10 MG TABLET

olanzapine and samidorphan L-malate
$55.2056per EA

Strength

5; 10 mg/1; mg/1

Manufacturer

Alkermes, Inc.

NDC

65757065142

Classification

Brand

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Approval Type

New Drug (NDA)

FDA Application

NDA213378

FDA Approved

5/28/2021

On Market Since

9/20/2021

Pharmacological Classes

Price Statistics

The NADAC for LYBALVI 5-10 MG TABLET has been published 223 times since May 18, 2022, and over the history we have for it it has risen 25.2%. The table below summarizes its recorded NADAC range and movement.

Current price$55.2056 per EA
All-time high$55.3304 (Jun 10, 2026)
All-time low$44.0963 (May 18, 2022)
52-week high$55.3304
52-week low$52.4318
Median price$50.1725
Average price$50.0531
Largest weekly change+5.5% (Nov 23, 2022)
Weeks tracked223
Tracking sinceMay 18, 2022

Price History

1W

-0.1%

1M

-0.1%

3M

-0.2%

6M

+0.1%

1Y

+5.3%

3Y

+14.2%

5Y

N/A

All

+25.2%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the olanzapine and samidorphan L-malate market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Frequently asked questions

What is the NADAC price of LYBALVI 5-10 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for LYBALVI 5-10 MG TABLET, manufactured by Alkermes, Inc., is $55.2056 per EA (NDC 65757065142), effective Aug 19, 2026.

How has the price of LYBALVI 5-10 MG TABLET changed over time?

Over the history we have for it, the NADAC for LYBALVI 5-10 MG TABLET has risen 25.2%. It has been tracked across 223 weekly CMS publications since May 18, 2022.

What are the highest and lowest recorded NADAC prices for LYBALVI 5-10 MG TABLET?

Since May 18, 2022, the NADAC for LYBALVI 5-10 MG TABLET has ranged from a low of $44.0963 (May 18, 2022) to a high of $55.3304 (Jun 10, 2026), with a median of $50.1725 per EA.

Are there cheaper alternatives to LYBALVI 5-10 MG TABLET?

No other NADAC-published product currently shares the active ingredient and strength of LYBALVI 5-10 MG TABLET in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures LYBALVI 5-10 MG TABLET?

LYBALVI 5-10 MG TABLET (NDC 65757065142) is labeled by Alkermes, Inc., and CMS classifies it as a brand product.