Product Information

LYBALVI 20-10 MG TABLET is a brand product labeled by Alkermes, Inc., priced at $55.0457 per EA under NDC 65757065442. Its NADAC has been published 219 times since Apr 20, 2022.

LYBALVI 20-10 MG TABLET

olanzapine and samidorphan L-malate
$55.0457per EA

Strength

20; 10 mg/1; mg/1

Manufacturer

Alkermes, Inc.

NDC

65757065442

Classification

Brand

Dosage Form

TABLET, FILM COATED

Route

ORAL

Last Updated

6/17/2026

Approval Type

New Drug (NDA)

FDA Application

NDA213378

On Market Since

9/20/2021

Pharmacological Classes

Price Statistics

The NADAC for LYBALVI 20-10 MG TABLET has been published 219 times since Apr 20, 2022, and over the history we have for it it has risen 24.3%. The table below summarizes its recorded NADAC range and movement.

Current price$55.0457 per EA
All-time high$55.1403 (Jun 10, 2026)
All-time low$44.2732 (Apr 20, 2022)
52-week high$55.1403
52-week low$52.2941
Median price$50.0750
Average price$49.7530
Largest weekly change+5.5% (Nov 23, 2022)
Weeks tracked219
Tracking sinceApr 20, 2022

Price History

1W

0.0%

1M

-0.2%

3M

+0.0%

6M

+5.0%

1Y

+5.3%

3Y

+17.5%

5Y

N/A

All

+24.3%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient, strength, and dosage form. Compare the broader picture on the olanzapine and samidorphan L-malate market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient, strength, and dosage form.

Frequently asked questions

What is the NADAC price of LYBALVI 20-10 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for LYBALVI 20-10 MG TABLET, manufactured by Alkermes, Inc., is $55.0457 per EA (NDC 65757065442), effective Jun 24, 2026.

How has the price of LYBALVI 20-10 MG TABLET changed over time?

Over the history we have for it, the NADAC for LYBALVI 20-10 MG TABLET has risen 24.3%. It has been tracked across 219 weekly CMS publications since Apr 20, 2022.

What are the highest and lowest recorded NADAC prices for LYBALVI 20-10 MG TABLET?

Since Apr 20, 2022, the NADAC for LYBALVI 20-10 MG TABLET has ranged from a low of $44.2732 (Apr 20, 2022) to a high of $55.1403 (Jun 10, 2026), with a median of $50.0750 per EA.

Are there cheaper alternatives to LYBALVI 20-10 MG TABLET?

No other NADAC-published product currently shares the active ingredient, strength, and dosage form of LYBALVI 20-10 MG TABLET, so no direct lower-cost alternative is listed.

Who manufactures LYBALVI 20-10 MG TABLET?

LYBALVI 20-10 MG TABLET (NDC 65757065442) is labeled by Alkermes, Inc., and CMS classifies it as a brand product.