Product Information
METHADONE HCL 10 MG TABLET is a generic product labeled by VistaPharm, LLC, priced at $0.1752 per EA under NDC 66689082010. Its NADAC has been published 145 times since Nov 15, 2023.
FDA first approved this application on May 29, 1998.
The Low Outlier badge above means this manufacturer's average price in the Methadone Hydrochloride market falls below Q1 − 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
10 mg/1
Manufacturer
VistaPharm, LLCNDC
66689082010
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
METHADONE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA040241FDA Approved
5/29/1998
On Market Since
11/22/2018
Pharmacological Classes
Price Statistics
The NADAC for METHADONE HCL 10 MG TABLET has been published 145 times since Nov 15, 2023, and over the history we have for it it has risen 12.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1752 per EA |
|---|---|
| All-time high | $0.2035 (Jul 16, 2025) |
| All-time low | $0.1472 (May 22, 2024) |
| 52-week high | $0.1954 |
| 52-week low | $0.1746 |
| Median price | $0.1803 |
| Average price | $0.1777 |
| Largest weekly change | +17.5% (Aug 21, 2024) |
| Weeks tracked | 145 |
| Tracking since | Nov 15, 2023 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 44% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of METHADONE HCL 10 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for METHADONE HCL 10 MG TABLET, manufactured by VistaPharm, LLC, is $0.1752 per EA (NDC 66689082010), effective Aug 19, 2026.
How has the price of METHADONE HCL 10 MG TABLET changed over time?
Over the history we have for it, the NADAC for METHADONE HCL 10 MG TABLET has risen 12.7%. It has been tracked across 145 weekly CMS publications since Nov 15, 2023.
What are the highest and lowest recorded NADAC prices for METHADONE HCL 10 MG TABLET?
Since Nov 15, 2023, the NADAC for METHADONE HCL 10 MG TABLET has ranged from a low of $0.1472 (May 22, 2024) to a high of $0.2035 (Jul 16, 2025), with a median of $0.1803 per EA.
Are there cheaper alternatives to METHADONE HCL 10 MG TABLET?
Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, METHADONE HCL 10 MG TABLET, is $0.0977 per EA — about 44% below METHADONE HCL 10 MG TABLET.
Who manufactures METHADONE HCL 10 MG TABLET?
METHADONE HCL 10 MG TABLET (NDC 66689082010) is labeled by VistaPharm, LLC, and CMS classifies it as a generic product.