Product Information
NITROGLYCERIN 400 MCG SPRAY is a generic product labeled by Prasco Laboratories, priced at $23.5234 per GM under NDC 66993024150. Its NADAC has been published 92 times since Jan 1, 2025.
FDA first approved this application on Oct 31, 1985. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
400 ug/1
Manufacturer
Prasco LaboratoriesNDC
66993024150
Classification
Generic
Dosage Form
SPRAY
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
NITROGLYCERINApproval Type
Authorized Generic (NDA)
FDA Application
NDA018705FDA Approved
10/31/1985
TE Code
AB
On Market Since
12/2/2024
Pharmacological Classes
Price Statistics
The NADAC for NITROGLYCERIN 400 MCG SPRAY has been published 92 times since Jan 1, 2025, and over the history we have for it it has declined 4.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $23.5234 per GM |
|---|---|
| All-time high | $27.7620 (Jul 16, 2025) |
| All-time low | $22.8743 (Jan 22, 2025) |
| 52-week high | $25.7224 |
| 52-week low | $22.9897 |
| Median price | $24.5659 |
| Average price | $24.9155 |
| Largest weekly change | +11.0% (Mar 19, 2025) |
| Weeks tracked | 92 |
| Tracking since | Jan 1, 2025 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 37% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Prasco Laboratories manufacturer profile
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Drug market
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Therapeutic class
Nitrate Vasodilator class view
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Trend hub
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of NITROGLYCERIN 400 MCG SPRAY?
The current National Average Drug Acquisition Cost (NADAC) for NITROGLYCERIN 400 MCG SPRAY, manufactured by Prasco Laboratories, is $23.5234 per GM (NDC 66993024150), effective Sep 30, 2026.
How has the price of NITROGLYCERIN 400 MCG SPRAY changed over time?
Over the history we have for it, the NADAC for NITROGLYCERIN 400 MCG SPRAY has declined 4.1%. It has been tracked across 92 weekly CMS publications since Jan 1, 2025.
What are the highest and lowest recorded NADAC prices for NITROGLYCERIN 400 MCG SPRAY?
Since Jan 1, 2025, the NADAC for NITROGLYCERIN 400 MCG SPRAY has ranged from a low of $22.8743 (Jan 22, 2025) to a high of $27.7620 (Jul 16, 2025), with a median of $24.5659 per GM.
Are there cheaper alternatives to NITROGLYCERIN 400 MCG SPRAY?
Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, NITROGLYCERIN 400 MCG SPRAY, is $14.9139 per GM — about 37% below NITROGLYCERIN 400 MCG SPRAY.
Who manufactures NITROGLYCERIN 400 MCG SPRAY?
NITROGLYCERIN 400 MCG SPRAY (NDC 66993024150) is labeled by Prasco Laboratories, and CMS classifies it as a generic product.