Product Information

PHENTERMINE-TOPIRAMATE ER 7.5-46 MG CAPSULE is a generic product labeled by Prasco Laboratories, priced at $3.2920 per EA under NDC 66993078130. Its NADAC has been published 53 times since Aug 20, 2025.

FDA first approved this application on Jul 17, 2012. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

PHENTERMINE-TOPIRAMATE ER 7.5-46 MG CAPSULE

phentermine and topiramate
$3.2920per EA
DEA Schedule CIV

Strength

7.5; 46 mg/1; mg/1

NDC

66993078130

Classification

Generic

Dosage Form

CAPSULE, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Approval Type

Authorized Generic (NDA)

FDA Application

NDA022580

FDA Approved

7/17/2012

TE Code

AB

On Market Since

6/1/2025

Pharmacological Classes

Appetite Suppression
Cytochrome P450 2C19 Inhibitors
Cytochrome P450 3A4 Inducers
Decreased Central Nervous System Disorganized Electrical Activity
Increased Sympathetic Activity
Sympathomimetic Amine Anorectic

Price Statistics

The NADAC for PHENTERMINE-TOPIRAMATE ER 7.5-46 MG CAPSULE has been published 53 times since Aug 20, 2025, and over the history we have for it it has declined 29.2%. The table below summarizes its recorded NADAC range and movement.

Current price$3.2920 per EA
All-time high$4.6508 (Sep 10, 2025)
All-time low$3.1410 (Feb 18, 2026)
52-week high$4.6508
52-week low$3.1410
Median price$3.3727
Average price$3.5793
Largest weekly change-14.2% (Sep 17, 2025)
Weeks tracked53
Tracking sinceAug 20, 2025

Price History

1W

-1.2%

1M

-1.2%

3M

+0.3%

6M

+4.8%

1Y

-29.2%

3Y

N/A

5Y

N/A

All

-29.2%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of PHENTERMINE-TOPIRAMATE ER 7.5-46 MG CAPSULE?

The current National Average Drug Acquisition Cost (NADAC) for PHENTERMINE-TOPIRAMATE ER 7.5-46 MG CAPSULE, manufactured by Prasco Laboratories, is $3.2920 per EA (NDC 66993078130), effective Aug 19, 2026.

How has the price of PHENTERMINE-TOPIRAMATE ER 7.5-46 MG CAPSULE changed over time?

Over the history we have for it, the NADAC for PHENTERMINE-TOPIRAMATE ER 7.5-46 MG CAPSULE has declined 29.2%. It has been tracked across 53 weekly CMS publications since Aug 20, 2025.

What are the highest and lowest recorded NADAC prices for PHENTERMINE-TOPIRAMATE ER 7.5-46 MG CAPSULE?

Since Aug 20, 2025, the NADAC for PHENTERMINE-TOPIRAMATE ER 7.5-46 MG CAPSULE has ranged from a low of $3.1410 (Feb 18, 2026) to a high of $4.6508 (Sep 10, 2025), with a median of $3.3727 per EA.

Are there cheaper alternatives to PHENTERMINE-TOPIRAMATE ER 7.5-46 MG CAPSULE?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as PHENTERMINE-TOPIRAMATE ER 7.5-46 MG CAPSULE in a comparable dosage form, but none are currently priced below it.

Who manufactures PHENTERMINE-TOPIRAMATE ER 7.5-46 MG CAPSULE?

PHENTERMINE-TOPIRAMATE ER 7.5-46 MG CAPSULE (NDC 66993078130) is labeled by Prasco Laboratories, and CMS classifies it as a generic product.