Product Information
DAPTOMYCIN 500 MG VIAL is a generic product labeled by Mylan Institutional LLC, priced at $22.6865 per EA under NDC 67457094115. Its NADAC has been published 123 times since Apr 17, 2024.
FDA first approved this application on Aug 7, 2023. Its Orange Book therapeutic-equivalence code is AP.
Strength
500 mg/10mL
Manufacturer
Mylan Institutional LLCNDC
67457094115
Classification
Generic
Dosage Form
INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
Route
INTRAVENOUS
Effective Date
8/19/2026
Active Ingredients
DAPTOMYCINApproval Type
Generic (ANDA)
FDA Application
ANDA213966FDA Approved
8/7/2023
TE Code
AP
On Market Since
11/27/2023
Pharmacological Classes
Price Statistics
The NADAC for DAPTOMYCIN 500 MG VIAL has been published 123 times since Apr 17, 2024, and over the history we have for it it has declined 8.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $22.6865 per EA |
|---|---|
| All-time high | $28.3900 (Sep 11, 2024) |
| All-time low | $20.1020 (Oct 22, 2025) |
| 52-week high | $24.2743 |
| 52-week low | $20.1020 |
| Median price | $21.9840 |
| Average price | $22.7536 |
| Largest weekly change | -17.2% (Oct 22, 2025) |
| Weeks tracked | 123 |
| Tracking since | Apr 17, 2024 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 8% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DAPTOMYCIN 500 MG VIAL?
The current National Average Drug Acquisition Cost (NADAC) for DAPTOMYCIN 500 MG VIAL, manufactured by Mylan Institutional LLC, is $22.6865 per EA (NDC 67457094115), effective Aug 19, 2026.
How has the price of DAPTOMYCIN 500 MG VIAL changed over time?
Over the history we have for it, the NADAC for DAPTOMYCIN 500 MG VIAL has declined 8.7%. It has been tracked across 123 weekly CMS publications since Apr 17, 2024.
What are the highest and lowest recorded NADAC prices for DAPTOMYCIN 500 MG VIAL?
Since Apr 17, 2024, the NADAC for DAPTOMYCIN 500 MG VIAL has ranged from a low of $20.1020 (Oct 22, 2025) to a high of $28.3900 (Sep 11, 2024), with a median of $21.9840 per EA.
Are there cheaper alternatives to DAPTOMYCIN 500 MG VIAL?
Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DAPTOMYCIN 500 MG VIAL, is $20.7686 per EA — about 8% below DAPTOMYCIN 500 MG VIAL.
Who manufactures DAPTOMYCIN 500 MG VIAL?
DAPTOMYCIN 500 MG VIAL (NDC 67457094115) is labeled by Mylan Institutional LLC, and CMS classifies it as a generic product.